How Metal Nuclearity Impacts Electrocatalytic H2 Production in Thiocarbohydrazone-Based Complexes

Autor: Michael Papadakis, Alexandre Barrozo, Léa Delmotte, Tatiana Straistari, Sergiu Shova, Marius Réglier, Vera Krewald, Sylvain Bertaina, Renaud Hardré, Maylis Orio

Publikováno v: Inorganics, Vol 11, Iss 4, p 149 (2023)

Thiocarbohydrazone-based catalysts feature ligands that are potentially electrochemically active. From the synthesis point of view, these ligands can be easily tailored, opening multiple strategies for optimization, such as using different substituen

Externí odkaz: https://doaj.org/article/bbbc7922f6904502910741a6be5adb2c

Exploiting HOPNO-dicopper center interaction to development of inhibitors for human tyrosinase

Autor: Elina Buitrago, Clarisse Faure, Marcello Carotti, Elisabetta Bergantino, Renaud Hardré, Marc Maresca, Christian Philouze, Nicolas Vanthuyne, Ahcène Boumendjel, Luigi Bubacco, Amaury du Moulinet d’Hardemare, Hélène Jamet, Marius Réglier, Catherine Belle

Publikováno v: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 2023, 248, pp.115090. ⟨10.1016/j.ejmech.2023.115090⟩

International audience; In human, Tyrosinase enzyme (TyH) is involved in the key steps of protective pigments biosynthesis (in skin, eyes and hair). The use of molecules targeting its binuclear copper active site represents a relevant strategy to reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf34e56eccee78d6f218516e3cf4b55
https://doi.org/10.1016/j.ejmech.2023.115090

Ditopic Chelators of Dicopper Centers for Enhanced Tyrosinases Inhibition

Autor: Christian Philouze, Elina Buitrago, Lylia Challali, Marc Maresca, Elisabetta Bergantino, Ahcène Boumendjel, Marius Réglier, Marcello Carotti, Luigi Bubacco, Catherine Belle, Clarisse Faure, Hélène Jamet, Renaud Hardré

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, 2021, 27 (13), pp.4384-4393. ⟨10.1002/chem.202004695⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2021, 27 (13), pp.4384-4393. ⟨10.1002/chem.202004695⟩

International audience; Tyrosinase enzymes (Tys) are involved in the key steps of melanin (protective pigments) biosynthesis and molecules targeting the binuclear copper active site on tyrosinases represent a relevant strategy to regulate enzyme acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669b6b51157dfe553a3b23aa61824495
https://pubmed.ncbi.nlm.nih.gov/33284485

New insight into the allosteric effect of L-tyrosine on mushroom tyrosinase during L-dopa production

Autor: Raymond L. Legge, Kamahldin Haghbeen, Sorour Hassani, Renaud Hardré, Somayeh Nikfard, Mostafa Fazli, Behzad Gharechaei, Nematollah Gheibi

Publikováno v: International Journal of Biological Macromolecules. 114:821-829

Kinetics studies of L-tyrosine (LTy) ortho-hydroxylation by mushroom tyrosinase (MT) confirmed that MT was severely, but not completely, inhibited at higher concentrations of LTy. Despite the availability of the crystal structure reports, no alloster

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09605338767653d8fb2f88e0ad92da17
https://doi.org/10.1016/j.ijbiomac.2018.03.185

Frontispiece: Hydrogen Evolution Reactions Catalyzed by a Bis(thiosemicarbazone) Cobalt Complex: An Experimental and Theoretical Study

Autor: Tatiana Straistari, Renaud Hardré, Jennifer Fize, Sergiu Shova, Michel Giorgi, Marius Réglier, Vincent Artero, Maylis Orio

Publikováno v: Chemistry - A European Journal. 24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7babf224b433d2245f3330822f610cdc
https://doi.org/10.1002/chem.201883565