Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Renato Scacchi"'
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35431 (2012)
Studies on human fertility genes have identified numerous risk/protective alleles involved in the occurrence of reproductive system diseases causing infertility or subfertility. Investigations we carried out in populations at natural fertility seem t
Externí odkaz:
https://doaj.org/article/f4dc973bd72143eeb5c6086cf08a0d5c
Publikováno v:
Journal of the Neurological Sciences. 344:149-153
The greater predisposition of women to Alzheimer's disease (AD), owing to the decrease in postmenopausal estrogen, may be influenced by polymorphic variation in genes regulating estrogen metabolism (e.g., COMT) and estrogen biosynthesis (e.g., CYP17)
Publikováno v:
International Journal of Geriatric Psychiatry. 29:610-615
Background Many factors could be responsible for the different response to treatment with the cholinesterase inhibitors (ChEIs) donepezil and rivastigmine in Alzheimer's disease (AD) patients. Sex and the variants of the estrogen receptor α (ESR1) g
Publikováno v:
Rejuvenation Research. 16:21-27
Men and women have different life expectancies. Not unexpectedly, several genes involved in life span determination have been found to influence the probability of achieving longevity differently in men and women. This investigation examines the asso
Publikováno v:
Clinica Chimica Acta. 412:1341-1344
Butyrylcholinesterase (BChE) and acetylcholinesterase (AchE) are two enzymes of the cholinergic system putatively involved in coronary artery disease (CAD). We investigated two single nucleotide polymorphisms (SNPs) of the genes encoding these enzyme
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 32:63-69
Background: The higher prevalence of sporadic Alzheimer’s disease (AD) in women may be explained by their longer life expectancy, but also by biological gender-specific factors such as a woman’s past fertility. Methods: We investigated the relati
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :51-55
Aromatase (CYP19) and estrogen receptor-alpha (ESR1) are involved in the metabolism of estrogens, which have a relevant role in female and male aging. Moreover, due to their influence on fertility, both genes may be part of the longevity-fertility tr
Autor:
Carlo Caltagirone, Ladson Hinton, M. Quintana, Brynjar Fure, Björn Hultberg, S. de Sola, Walter Valfrè, Elisa Rubino, Ronald E. Gangnon, Massimo Musicco, Mary N. Haan, Giuseppina D’Amico, Giuseppe Gambina, Jane E. Mahoney, Leiv Sandvik, Laurel A. Beckett, Douglas Hinerfeld, Serena Mosti, Jørgen Wagle, Peter St George-Hyslop, Lorenzo Pinessi, Brynhild Stensrød, G. Sánchez-Benavides, Patrizia Ferrero, Yan Li, Salvatore Gallone, Carey E. Gleason, Richard J. Caselli, Giuseppe Moretto, Yolanda Hagar, J. Peña-Casanova, Denisa Baci, Giovanna Vaula, L Ulizzi, Stephen P. Baker, Ekaterina Rogaeva, Renato Scacchi, Giorgetta Cappa, Karin Nilsson, Barbara L. Fischer, Lars Gustafson, Keith A. Josephs, Ping-Yiu Yik, Eugenia Rota, Knut Engedal, R.M. Manero, Bradley F. Boeve, Barbara A. Evans, Leung-Wing Chu, S. Quiñones-Úbeda, Rosa Maria Corbo, Torgeir Bruun Wyller, Luca Cravello, Zhong Li, Preben Bo Mortensen, Concetta Di Lorenzo, Innocenzo Rainero, Alexander Kurz, Lars Vedel Kessing, James E. Evans, Katie Palmer, Majaz Moonis, Kevin J. Kane, Thien Kieu Thi Phung, Kjell Flekkøy, Kristin L. Eiklid, Brendan J. Kelley, Hector M. González, Giovanna Salamone, Joan M. Swearer, You-Qiang Song, Horst Bickel, Nancy West, Gunhild Waldemar, Daniel A. Pollen, P Fenoglio, Federica Lupo, Lasse Farner, Birgitte Bo Andersen, Dan M Mungas
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 27:I-VI
Publikováno v:
Rejuvenation research. 18(5)
Evolutionary theories of aging predict an antagonistic relationship between fertility and life span in humans, but the genetic basis of this phenomenon is not clear. The variation of three genes in steroid hormone metabolism--CYP17 (rs743572), HSD17B
Autor:
Giuseppe Moretto, G. Gambina, Vincent Raussens, Rosa Maria Corbo, Martine Prévost, Renato Scacchi
Publikováno v:
Molecular genetics and metabolism
89 (2006): 261–269. doi:10.1016/j.ymgme.2006.02.015
info:cnr-pdr/source/autori:Corbo RM; Prevost M; Raussens V; Gambina G; Moretto G; Scacchi R/titolo:Structural and phylogenetic approaches to assess the significance of human Apolipoprotein E variation./doi:10.1016%2Fj.ymgme.2006.02.015/rivista:Molecular genetics and metabolism (Print)/anno:2006/pagina_da:261/pagina_a:269/intervallo_pagine:261–269/volume:89
89 (2006): 261–269. doi:10.1016/j.ymgme.2006.02.015
info:cnr-pdr/source/autori:Corbo RM; Prevost M; Raussens V; Gambina G; Moretto G; Scacchi R/titolo:Structural and phylogenetic approaches to assess the significance of human Apolipoprotein E variation./doi:10.1016%2Fj.ymgme.2006.02.015/rivista:Molecular genetics and metabolism (Print)/anno:2006/pagina_da:261/pagina_a:269/intervallo_pagine:261–269/volume:89
Apolipoprotein E (APOE) is an important gene whose common polymorphism, and precisely the e*4 allele, has been reportedly associated with some disorders, including Alzheimer's disease (AD) and coronary artery disease. In the course of previous survey