Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Renato J Aguilera"'
Autor:
Risa Mia Swain, Anahi Sanchez, Denisse A Gutierrez, Armando Varela-Ramirez, Renato J Aguilera
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0295441 (2023)
In an effort to identify novel anti-cancer agents, we employed a well-established High Throughput Screening (HTS) assay to assess the cytotoxic effect of compounds within the ChemBridge DIVERSet Library on a lymphoma cell line. This screen revealed a
Externí odkaz:
https://doaj.org/article/22eb3a64c5784de581e7394bb2be19e0
Autor:
Alexander Philipovskiy, Alok K Dwivedi, Roberto Gamez, Richard McCallum, Debabrata Mukherjee, Zeina Nahleh, Renato J Aguilera, Sumit Gaur
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238262 (2020)
Triple-negative breast cancer (TNBC) represents 15%-20% of all breast cancer types. It is more common among African American (AA) and Hispanic-Latina (HL) women. The biology of TNBC in HL women has been poorly characterized, but some data suggest tha
Externí odkaz:
https://doaj.org/article/7ce66c3f345d45bbb509766b7d75dd10
Autor:
Paulina J Villanueva, Alberto Martinez, Sarah T Baca, Rebecca E DeJesus, Manuel Larragoity, Lisett Contreras, Denisse A Gutierrez, Armando Varela-Ramirez, Renato J Aguilera
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206467 (2018)
The potent antimalarial drug pyronaridine (PND) was tested for its potential as an anticancer drug. After exposing cancerous (17) and non-cancerous (2) cells to PND for 72 hr, PND was found to exhibit consistent and potent cytotoxic activity at low m
Externí odkaz:
https://doaj.org/article/8e1041405ca847759a40a39062954a98
Autor:
Chang-Soo Seong, Armando Varela-Ramirez, Xiaolei Tang, Brenda Anchondo, Diego Magallanes, Renato J Aguilera
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103564 (2014)
Drosophila melanogaster flies mount an impressive immune response to a variety of pathogens with an efficient system comprised of both humoral and cellular responses. The fat body is the main producer of the anti-microbial peptides (AMPs) with anti-p
Externí odkaz:
https://doaj.org/article/7886fef94c924aca876f3a9073419820
Autor:
Elisa Robles-Escajeda, Dennise Lerma, Alice M Nyakeriga, Jeremy A Ross, Robert A Kirken, Renato J Aguilera, Armando Varela-Ramirez
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73508 (2013)
Green barley extract (GB) was investigated for possible anti-cancer activity by examining its anti-proliferative and pro-apoptotic properties on human leukemia/lymphoma cell lines. Our results indicate that GB exhibits selective anti-proliferative ac
Externí odkaz:
https://doaj.org/article/65f6f91c1aba4c839c8b45c017e98b0e
Autor:
Michael Boyce, Renato J. Aguilera
Publikováno v:
BMC Proceedings, Vol 15, Iss S2, Pp 1-10 (2021)
Abstract At research-intensive universities in the United States, eligible faculty must generally excel in research, teaching and service in order to receive tenure. To meet these high standards, junior faculty should begin planning for a strong tenu
Externí odkaz:
https://doaj.org/article/803d036d50fb456797d2b56545ce781a
Autor:
Yangcheng Ma, Cuipeng Qiu, Bofei Wang, Xiaojun Zhang, Xiao Wang, Renato J. Aguilera, Jian-Ying Zhang
Publikováno v:
Cells, Vol 11, Iss 20, p 3227 (2022)
Background: Tumor-associated antigens (TAAs) have been investigated for many years as potential early diagnosis tools, especially for hepatocellular carcinoma (HCC). Nonetheless, very few studies have focused on the Hispanic HCC group that may be ass
Externí odkaz:
https://doaj.org/article/ccff207cd33f4a21aa7a2ec72d5d3608
Autor:
Aruna Chhikara, Praveen K. Roayapalley, Hiroshi Sakagami, Shigeru Amano, Keitaro Satoh, Yoshihiro Uesawa, Umashankar Das, Swagatika Das, Edgar A. Borrego, Cristina D. Guerena, Clare R. Hernandez, Renato J. Aguilera, Jonathan R. Dimmock
Publikováno v:
Molecules, Vol 27, Iss 19, p 6718 (2022)
Two series of novel unsymmetrical 3,5-bis(benzylidene)-4 piperidones 2a–f and 3a–e were designed as candidate antineoplastic agents. These compounds display potent cytotoxicity towards two colon cancers, as well as several oral squamous cell carc
Externí odkaz:
https://doaj.org/article/2a31bd5df66d4cda8c251e729ecf8583
Autor:
Jessica D. Hess, Luca H. Macias, Denisse A. Gutierrez, Karla Moran-Santibanez, Lisett Contreras, Stephanie Medina, Paulina J. Villanueva, Robert A. Kirken, Armando Varela-Ramirez, Manuel L. Penichet, Renato J. Aguilera
Publikováno v:
Biology, Vol 11, Iss 6, p 930 (2022)
In recent years, the thienopyrazole moiety has emerged as a pharmacologically active scaffold with antitumoral and kinase inhibitory activity. In this study, high-throughput screening of 2000 small molecules obtained from the ChemBridge DIVERset libr
Externí odkaz:
https://doaj.org/article/ecd0ac3c2f914b6c81921427813e37b2
Autor:
Md Nurul Huda, Edgar A. Borrego, Cristina D. Guerena, Armando Varela-Ramirez, Renato J. Aguilera, Christine M. Hamadani, Eden E. L. Tanner, Abu Zayed Md Badruddoza, Sandeep K. Agarwal, Md Nurunnabi
Publikováno v:
ACS Pharmacology & Translational Science. 6:829-841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecf1947cf428f7dd7c8f1297851afc1e
https://doi.org/10.1021/acsptsci.3c00039
https://doi.org/10.1021/acsptsci.3c00039