Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Renato Baserga"'
Autor:
Frank J. Calzone, Robert Radinsky, Richard Kendall, Renato Baserga, Steven Vonderfecht, Min Zhu, Mei Mei Tsai, Joanne Ho, Brian Belmontes, John Lu, Elaina Cajulis, Young-A Chung, Petia Mitchell, Pedro J. Beltran
Supplementary Table S1 from AMG 479, a fully human anti–insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f79010b4da94ca43305e44737cbaf00
https://doi.org/10.1158/1535-7163.22485659
https://doi.org/10.1158/1535-7163.22485659
Autor:
Frank J. Calzone, Robert Radinsky, Richard Kendall, Renato Baserga, Steven Vonderfecht, Min Zhu, Mei Mei Tsai, Joanne Ho, Brian Belmontes, John Lu, Elaina Cajulis, Young-A Chung, Petia Mitchell, Pedro J. Beltran
Pancreatic carcinoma is a leading cause of cancer deaths, and recent clinical trials of a number of oncology therapeutics have not substantially improved clinical outcomes. We have evaluated the therapeutic potential of AMG 479, a fully human monoclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d848837cc9c0c0143eba8b9957be18
https://doi.org/10.1158/1535-7163.c.6532043
https://doi.org/10.1158/1535-7163.c.6532043
Autor:
Frank J. Calzone, Robert Radinsky, Richard Kendall, Renato Baserga, Steven Vonderfecht, Min Zhu, Mei Mei Tsai, Joanne Ho, Brian Belmontes, John Lu, Elaina Cajulis, Young-A Chung, Petia Mitchell, Pedro J. Beltran
Supplementary Fig. S1 from AMG 479, a fully human anti–insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ac6050232749c915bc3dd653f5ecad
https://doi.org/10.1158/1535-7163.22485662
https://doi.org/10.1158/1535-7163.22485662
Autor:
Susan R. Rittling, Renato Baserga
Publikováno v:
Growth Control During Cell Aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5deefbdebb92e27280998d8f8704dbfa
https://doi.org/10.1201/9781003068150-5
https://doi.org/10.1201/9781003068150-5
Autor:
Tiziana DeAngelis, Senthamil R. Selvan, Michael J. Mastrangelo, Renato Baserga, Makoto Yoshida, Peter McCue, Hallgeir Rui, Ami Fujii, Takami Sato
Publikováno v:
Pigment Cell & Melanoma Research. 27:297-308
We investigated the importance of the insulin-like growth factor-1 receptor (IGF-1R) in hepatic metastases of uveal melanoma. The expression pattern of IGF-1R in archival tissue samples of hepatic metastasis from 24 patients was analyzed by immunohis
Autor:
Renato Baserga, Federica Sotgia, Michael P. Lisanti, Nicole L. Simone, Mark V. Mishra, Richard G. Pestell, Colin E. Champ, Lianjin Jin, Adam P. Dicker
Publikováno v:
The Oncologist. 18:97-103
CME Learning Objectives Identify molecular pathways that are potential targets of calorie restriction combined with radiation therapy. Identify cancer patients for whom calorie restriction would be contraindicated. Calorie restriction (CR), or a diet
Autor:
Renato Baserga
Publikováno v:
Journal of Cellular Physiology. 228:675-679
This review examines the effect of targeting the insulin-like growth factor 1 receptor (IGF-IR) in human cancers. The results are disappointing. The causes for the failure are discussed, as well as the possible use of the IGF-IR as a secondary target
Publikováno v:
Cell Cycle. 10:1956-1959
The mammalian homolog of the Drosophila dachshund gene (DACH1) has been reported as a tumor suppressor in human breast and prostate cancers. It downregulates the epidermal growth factor receptor (EGFR) and cyclin D1. The signaling pathway of the type
Autor:
Bin Shi, Laura Sepp-Lorenzinoi, Margherita Badin, Tiziana DeAngelis, Renato Baserga, Shi-Qiong Xu, Gaspare La Rocca
Publikováno v:
Journal of Cellular Physiology. 220:485-491
MicroRNA 145 (miR145) has been proposed as a tumor suppressor. It was previously shown that miR145 targets the 3′ UTR of the insulin receptor substrate-1 (IRS-1) and dramatically inhibits the growth of colon cancer cells. miR145 also targets the ty
Autor:
Margherita Badin, Laura Sepp-Lorenzino, Tiziana De Angelis, Gaspare La Rocca, Bin Shi, Renato Baserga
Publikováno v:
Cell Cycle. 8:2255-2259
We have examined several microRNAs (miRs) indicated by the databases as targeting the signaling pathway of the type-1 insulin-like growth factor receptor (IGF-IR). Most of the miRs tested had multiple targets, as expected, leading to cell death. Howe