Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Renate Parry"'
Autor:
Mary Helen Barcellos-Hoff, Matthew H. Spitzer, Diana M. Marquez, Iliana Tenvooren, Renate Parry, Ritu Roy, Chen Hao Lo, Shisuo Du, Ilenia Pellicciotta, Kyla E. Driscoll, Alba Gonzalez-Junca
Supplemental tables and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72342dde3a191f42a840b3ac2be68c85
https://doi.org/10.1158/2326-6066.22539725
https://doi.org/10.1158/2326-6066.22539725
Autor:
Mary Helen Barcellos-Hoff, Matthew H. Spitzer, Diana M. Marquez, Iliana Tenvooren, Renate Parry, Ritu Roy, Chen Hao Lo, Shisuo Du, Ilenia Pellicciotta, Kyla E. Driscoll, Alba Gonzalez-Junca
Transforming growth factor β (TGFβ) is an effector of immune suppression and contributes to a permissive tumor microenvironment that compromises effective immunotherapy. We identified a correlation between TGFB1 and genes expressed by myeloid cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c05a7ab81743ac923e1538510fddefb
https://doi.org/10.1158/2326-6066.c.6549167.v1
https://doi.org/10.1158/2326-6066.c.6549167.v1
Autor:
Ralph R. Weichselbaum, Nikolai N. Khodarev, George-Lucian Moldovan, Stephen J. Kron, Renate Parry, Ainhoa Arina, Michael J. Bolt, Xiaona Huang, Claudia M. Nicolae, Akash D. Parekh, Stephen Mallon, Ryan C. Widau, Diana Rose E. Ranoa
(A) Quantification of bands from Western gel shown in Main Figure 3A using Image J. The pixel units obtained for each protein band was normalized to the pixel units calculated from their respective b-Actin loading control. (B-G) Clonogenic survival o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c91028c76ea48a7af241d56469ca53f
https://doi.org/10.1158/0008-5472.22423802
https://doi.org/10.1158/0008-5472.22423802
Autor:
Ralph R. Weichselbaum, Nikolai N. Khodarev, George-Lucian Moldovan, Stephen J. Kron, Renate Parry, Ainhoa Arina, Michael J. Bolt, Xiaona Huang, Claudia M. Nicolae, Akash D. Parekh, Stephen Mallon, Ryan C. Widau, Diana Rose E. Ranoa
(A) Quantification of bands from Western gel shown in Main Figure 5D using Image J. The pixel units obtained for each protein band was normalized to the pixel units calculated from their respective b-Actin loading control. (B-E) Kinetic analysis of W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16bc85bcb68b6b50eb309456ae05d6c4
https://doi.org/10.1158/0008-5472.22423787.v1
https://doi.org/10.1158/0008-5472.22423787.v1
Autor:
Ralph R. Weichselbaum, Nikolai N. Khodarev, George-Lucian Moldovan, Stephen J. Kron, Renate Parry, Ainhoa Arina, Michael J. Bolt, Xiaona Huang, Claudia M. Nicolae, Akash D. Parekh, Stephen Mallon, Ryan C. Widau, Diana Rose E. Ranoa
(A-D) Quantification of bands from Western gels shown in Main Figures 3H (A), 3I (B), 3J (C), and 3K (D) using Image J. The pixel units obtained for each protein band was normalized to the pixel units calculated from their respective b-Actin loading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22bb8269581573bae51c00a234fc886
https://doi.org/10.1158/0008-5472.22423799.v1
https://doi.org/10.1158/0008-5472.22423799.v1
Autor:
Ralph R. Weichselbaum, Nikolai N. Khodarev, George-Lucian Moldovan, Stephen J. Kron, Renate Parry, Ainhoa Arina, Michael J. Bolt, Xiaona Huang, Claudia M. Nicolae, Akash D. Parekh, Stephen Mallon, Ryan C. Widau, Diana Rose E. Ranoa
WT and STING-/- MEFs examined by cytokinesis-block micronucleus (CBMN) assay by treatment with IR, then cytochalasin at 24 hours and then fixed and stained for DNA and mitochondrial/cytoplasmic compartments using Draq5 and MitoTracker Red at 48 hours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ce72cbd009f095d6431b46b6d310e5
https://doi.org/10.1158/0008-5472.22423793
https://doi.org/10.1158/0008-5472.22423793
Autor:
Ralph R. Weichselbaum, Nikolai N. Khodarev, George-Lucian Moldovan, Stephen J. Kron, Renate Parry, Ainhoa Arina, Michael J. Bolt, Xiaona Huang, Claudia M. Nicolae, Akash D. Parekh, Stephen Mallon, Ryan C. Widau, Diana Rose E. Ranoa
(A-C) BrdU/PI cell cycle profile of MEFs (A), p53-/- HCT116 (B), and CDKN1A-depleted HCT116 cells (C) at 24 hours post-IR. Flow cytometry was used to measure the percent cell population in G1, S, and G2/M phase of single cells stained with FITC-conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0318fc602b5256c27fd73b12debf58c9
https://doi.org/10.1158/0008-5472.22423790
https://doi.org/10.1158/0008-5472.22423790
Autor:
Ralph R. Weichselbaum, Nikolai N. Khodarev, George-Lucian Moldovan, Stephen J. Kron, Renate Parry, Ainhoa Arina, Michael J. Bolt, Xiaona Huang, Claudia M. Nicolae, Akash D. Parekh, Stephen Mallon, Ryan C. Widau, Diana Rose E. Ranoa
Given the integral role of stimulator of interferon genes (STING, TMEM173) in the innate immune response, its loss or impairment in cancer is thought to primarily affect antitumor immunity. Here we demonstrate a role for STING in the maintenance of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7eca93a436663f8ce8eb450b16eab2e
https://doi.org/10.1158/0008-5472.c.6511583.v1
https://doi.org/10.1158/0008-5472.c.6511583.v1
Autor:
Ralph R. Weichselbaum, Nikolai N. Khodarev, George-Lucian Moldovan, Stephen J. Kron, Renate Parry, Ainhoa Arina, Michael J. Bolt, Xiaona Huang, Claudia M. Nicolae, Akash D. Parekh, Stephen Mallon, Ryan C. Widau, Diana Rose E. Ranoa
Cell cycle profile of pulse EdU-labeled (A) and chase EdU-labeled (B) WT and STING-/- MEFs at different time points post-IR treatment. Flow cytometry was used to measure the percent cell population in G1, S, and G2/M phase of single cells stained wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742e15e9cf6e993d18aca225111b4f58
https://doi.org/10.1158/0008-5472.22423805
https://doi.org/10.1158/0008-5472.22423805
Autor:
Ralph R. Weichselbaum, Nikolai N. Khodarev, George-Lucian Moldovan, Stephen J. Kron, Renate Parry, Ainhoa Arina, Michael J. Bolt, Xiaona Huang, Claudia M. Nicolae, Akash D. Parekh, Stephen Mallon, Ryan C. Widau, Diana Rose E. Ranoa
Western blot analysis of multiple stable D54 (A), HCT116 (B), and MC-38 (C) cell lines expressing short hairpin RNAs targeting STING or scrambled control (SHCOO2). Quantified bands are shown below each of their respective Western blot panels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82a60d2f417654d1dd0d78fc1898c24
https://doi.org/10.1158/0008-5472.22423808.v1
https://doi.org/10.1158/0008-5472.22423808.v1