Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Renate M Lewis"'
Autor:
Antonietta Franco, Jiajia Li, Daniel P Kelly, Ray E Hershberger, Ali J Marian, Renate M Lewis, Moshi Song, Xiawei Dang, Alina D Schmidt, Mary E Mathyer, John R Edwards, Cristina de Guzman Strong, Gerald W Dorn
Publikováno v:
eLife, Vol 12 (2023)
Cardiac muscle has the highest mitochondrial density of any human tissue, but mitochondrial dysfunction is not a recognized cause of isolated cardiomyopathy. Here, we determined that the rare mitofusin (MFN) 2 R400Q mutation is 15–20× over-represe
Externí odkaz:
https://doaj.org/article/c8163fadb630467b8faefb631505c99f
Autor:
Antonietta Franco, Jiajia Li, Daniel P. Kelly, Ray E. Hershberger, Ali J. Marian, Renate M. Lewis, Moshi Song, Xiawei Dang, Alina D. Schmidt, Mary E. Mathyer, Cristina de Guzman Strong, Gerald W. Dorn
Cardiac muscle has the highest mitochondrial density of any human tissue, but mitochondrial dysfunction is not a recognized cause of isolated cardiomyopathy. Here, we determined that the rare mitofusin (MFN) 2 R400Q mutation is ~20x over-represented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e12c0e9e7e12b7bfd685e659c6f90a
https://doi.org/10.1101/2022.11.22.517462
https://doi.org/10.1101/2022.11.22.517462
Autor:
Sean Brophy, Scott M. Lee, Michael J. Vasek, Lorida Llaci, Renate M. Lewis, Joseph D. Dougherty, Susan E. Maloney, Yating Liu, Michael A. Rieger, Eric Tycksen, Kristina Sakers
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Quaking RNA binding protein (QKI) is essential for oligodendrocyte development as myelination requires myelin basic protein mRNA regulation and localization by the cytoplasmic isoforms (e.g., QKI-6). QKI-6 is also highly expressed in astrocytes, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d822c5bc18659b2383e51136796911
https://doi.org/10.1038/s41467-021-21703-5
https://doi.org/10.1038/s41467-021-21703-5
Autor:
Yating Liu, Michael A. Rieger, Sean Brophy, Michael J. Vasek, Lorida Llaci, Joseph D. Dougherty, Kristina Sakers, Renate M. Lewis, Eric Tycksen, Susan E. Maloney
Quaking RNA binding protein(QKI) is essential for oligodendrocyte development as myelination requires MBP mRNA regulation and localization by the cytoplasmic isoforms(e.g. QKI-6). QKI-6 is also highly expressed in astrocytes, which were recently demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8648a684027870f0372d05b34ee71085
Autor:
Mohammad K. Hajihosseini, Estela Pérez-Santamarina, Craig Smith, Irene H. Hung, Andrew S. Hagan, Mark Lewandoski, Renate M. Lewis, Karolina Kowalska, Michael Boylan, David M. Ornitz
BACKGROUND: Fibroblast growth factor 18 (FGF18) functions in the development of several tissues, including the lung, limb bud, palate, skeleton, central nervous system, and hair follicle. Mice containing a germline knockout of Fgf18 (Fgf18(−/−))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff38d74021c194c1dca8352d35e6eeee
https://ueaeprints.uea.ac.uk/id/eprint/71826/
https://ueaeprints.uea.ac.uk/id/eprint/71826/
Autor:
Vivian Lam, Rachel O.L. Wong, Yuan Ge, Ann Marie Craig, Renate M. Lewis, Robert Cassidy, Robert S. Molday, Lin Luo, Kyung Mee Moon, Yunhee Kang, Leonard J. Foster
Publikováno v:
Journal of Biological Chemistry. 289:29350-29364
Synapses, the basic units of communication in the brain, require complex molecular machinery for neurotransmitter release and reception. Whereas numerous components of excitatory postsynaptic sites have been identified, relatively few proteins are kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d64300ada6947800d0276ff3d4f2b5
https://doi.org/10.1074/jbc.m114.549279
https://doi.org/10.1074/jbc.m114.549279
Autor:
Russell J. Fernandes, Louisa Wirthlin, Renate M. Lewis, Soumya Ravindran, Geoffrey Traeger, Audrey McAlinden
Publikováno v:
Matrix Biology. 31:214-226
The present study describes the generation of a knock-in mouse model to address the role of type II procollagen (Col2a1) alternative splicing in skeletal development and maintenance. Alternative splicing of Col2a1 precursor mRNA is a developmentally-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5043e012b23a1159b7e4c0fbf6aab85
https://doi.org/10.1016/j.matbio.2011.12.004
https://doi.org/10.1016/j.matbio.2011.12.004
Autor:
Leonard J. Foster, Rachel O.L. Wong, Ann Marie Craig, Renate M. Lewis, Yunhee Kang, Yuan Ge, Robert Cassidy, Kyung-Mee Moon
Publikováno v:
Neuron. 97:596-610.e8
In contrast with numerous studies of glutamate receptor-associated proteins and their involvement in the modulation of excitatory synapses, much less is known about mechanisms controlling postsynaptic GABAA receptor (GABAAR) numbers. Using tandem aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559f2e67abe5067b5a0cf3a9cd6c771c
https://doi.org/10.1016/j.neuron.2017.12.038
https://doi.org/10.1016/j.neuron.2017.12.038
Publikováno v:
Nature
Activity is presumed to help shape the connectivity within neural circuits, with differences often leading to the elimination of less active connections. Here, to challenge this notion, a subpopulation of bipolar cells was inactivated during developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1508814d0fc40e8bdf56cdd848eab50f
https://doi.org/10.1038/nature08236
https://doi.org/10.1038/nature08236
Autor:
Renate M. Lewis, Joshua R. Sanes, Jean-Michel Longpré, Richard Leduc, Lauren W. Wang, Robert P.T. Somerville, Elizabeth D. Apel, Suneel S. Apte
Publikováno v:
Journal of Biological Chemistry. 279:35159-35175
We have characterized ADAMTS7B, the authentic full-length protein product of the ADAMTS7 gene. ADAMTS7B has a domain organization similar to that of ADAMTS12, with a total of eight thrombospondin type 1 repeats in its ancillary domain. Of these, seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8377f5b8788c3b618dd4a0a49b04e160
https://doi.org/10.1074/jbc.m402380200
https://doi.org/10.1074/jbc.m402380200