Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Renate Kirschner-Schwabe"'
Autor:
Tamara Kempter, Paulina Richter-Pechanska, Katarzyna Michel, Tobias Rausch, Büşra Erarslan-Uysal, Cornelia Eckert, Martin Zimmermann, Martin Stanulla, Martin Schrappe, Gunnar Cario, Renate Kirschner-Schwabe, Stefan Koehrer, Jan Korbel, Joachim Kunz, Andreas E Kulozik
Publikováno v:
HemaSphere, Vol 7, p e9493074 (2023)
Externí odkaz:
https://doaj.org/article/77ee918485564004bb875af4218b482e
Autor:
Yan Xu, Houshun Fang, Yao Chen, Yabin Tang, Huiying Sun, Ziqing Kong, Fan Yang, Renate Kirschner-Schwabe, Liang Zhu, Alex Toker, Ning Xiao, Bin-Bing S. Zhou, Hui Li
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103881- (2022)
Summary: Mutations in RAS pathway genes are highly prevalent in acute lymphoblastic leukemia (ALL). However, the effects of RAS mutations on ALL cell growth have not been experimentally characterized, and effective RAS-targeting therapies are being s
Externí odkaz:
https://doaj.org/article/40e05a2d452446e8a0089403384e9b42
Autor:
Büşra Erarslan‐Uysal, Joachim B Kunz, Tobias Rausch, Paulina Richter‐Pechańska, Ianthe AEM van Belzen, Viktoras Frismantas, Beat Bornhauser, Diana Ordoñez‐Rueada, Malte Paulsen, Vladimir Benes, Martin Stanulla, Martin Schrappe, Gunnar Cario, Gabriele Escherich, Kseniya Bakharevich, Renate Kirschner‐Schwabe, Cornelia Eckert, Tsvetomir Loukanov, Matthias Gorenflo, Sebastian M Waszak, Jean‐Pierre Bourquin, Martina U Muckenthaler, Jan O Korbel, Andreas E Kulozik
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp 1-14 (2020)
Abstract We aimed at identifying the developmental stage at which leukemic cells of pediatric T‐ALLs are arrested and at defining leukemogenic mechanisms based on ATAC‐Seq. Chromatin accessibility maps of seven developmental stages of human healt
Externí odkaz:
https://doaj.org/article/22d6864d026e473bab1f5a0e5f21e0cf
Autor:
Alva Rani James, Michael P. Schroeder, Martin Neumann, Lorenz Bastian, Cornelia Eckert, Nicola Gökbuget, Jutta Ortiz Tanchez, Cornelia Schlee, Konstandina Isaakidis, Stefan Schwartz, Thomas Burmeister, Arend von Stackelberg, Michael A. Rieger, Stefanie Göllner, Martin Horstman, Martin Schrappe, Renate Kirschner-Schwabe, Monika Brüggemann, Carsten Müller-Tidow, Hubert Serve, Altuna Akalin, Claudia D. Baldus
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Long non-coding RNAs (lncRNAs) have emerged as a novel class of RNA due to its diverse mechanism in cancer development and progression. However, the role and expression pattern of lncRNAs in molecular subtypes of B cell acute lymp
Externí odkaz:
https://doaj.org/article/0239516c3301412db8a7d3731f5b8443
Autor:
Paulina Richter‐Pechańska, Joachim B Kunz, Beat Bornhauser, Caroline von Knebel Doeberitz, Tobias Rausch, Büşra Erarslan‐Uysal, Yassen Assenov, Viktoras Frismantas, Blerim Marovca, Sebastian M Waszak, Martin Zimmermann, Julia Seemann, Margit Happich, Martin Stanulla, Martin Schrappe, Gunnar Cario, Gabriele Escherich, Kseniya Bakharevich, Renate Kirschner‐Schwabe, Cornelia Eckert, Martina U Muckenthaler, Jan O Korbel, Jean‐Pierre Bourquin, Andreas E Kulozik
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp 1-13 (2018)
Abstract We compared 24 primary pediatric T‐cell acute lymphoblastic leukemias (T‐ALL) collected at the time of initial diagnosis and relapse from 12 patients and 24 matched patient‐derived xenografts (PDXs). DNA methylation profile was preserv
Externí odkaz:
https://doaj.org/article/a41b214baa0c4e7083befa1edbc53289
Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia?
Autor:
Claire Schwab, Karin Nebral, Lucy Chilton, Cristina Leschi, Esmé Waanders, Judith M. Boer, Markéta Žaliová, Rosemary Sutton, Ingegerd Ivanov Öfverholm, Kentaro Ohki, Yuka Yamashita, Stefanie Groeneveld-Krentz, Eva Froňková, Marleen Bakkus, Joelle Tchinda, Thayana da Conceição Barbosa, Grazia Fazio, Wojciech Mlynarski, Agata Pastorczak, Giovanni Cazzaniga, Maria S. Pombo-de-Oliveira, Jan Trka, Renate Kirschner-Schwabe, Toshihiko Imamura, Gisela Barbany, Martin Stanulla, Andishe Attarbaschi, Renate Panzer-Grümayer, Roland P. Kuiper, Monique L. den Boer, Hélène Cavé, Anthony V. Moorman, Christine J. Harrison, Sabine Strehl
Publikováno v:
Blood Advances, Vol 1, Iss 19, Pp 1473-1477 (2017)
Externí odkaz:
https://doaj.org/article/64841652a85648169d0a262aedd8c662
Autor:
Jana Hof, Corinne Kox, Stefanie Groeneveld-Krentz, Obul R. Bandapalli, Leonid Karawajew, Katharina Schedel, Joachim B. Kunz, Cornelia Eckert, Wolf-Dieter Ludwig, Richard Ratei, Peter Rhein, Günter Henze, Martina U. Muckenthaler, Andreas E. Kulozik, Arend von Stackelberg, Renate Kirschner-Schwabe
Publikováno v:
Haematologica, Vol 102, Iss 7 (2017)
Externí odkaz:
https://doaj.org/article/987d27552bb84979998f86731dd7813b
Autor:
Joachim B. Kunz, Tobias Rausch, Obul R. Bandapalli, Juliane Eilers, Paulina Pechanska, Stephanie Schuessele, Yassen Assenov, Adrian M. Stütz, Renate Kirschner-Schwabe, Jana Hof, Cornelia Eckert, Arend von Stackelberg, Martin Schrappe, Martin Stanulla, Rolf Koehler, Smadar Avigad, Sarah Elitzur, Rupert Handgretinger, Vladimir Benes, Joachim Weischenfeldt, Jan O. Korbel, Martina U. Muckenthaler, Andreas E. Kulozik
Publikováno v:
Haematologica, Vol 100, Iss 11 (2015)
Relapsed precursor T-cell acute lymphoblastic leukemia is characterized by resistance against chemotherapy and is frequently fatal. We aimed at understanding the molecular mechanisms resulting in relapse of T-cell acute lymphoblastic leukemia and ana
Externí odkaz:
https://doaj.org/article/46500b812ed74866a1f64e67d1035354
Autor:
Obul R. Bandapalli, Stephanie Schuessele, Joachim B. Kunz, Tobias Rausch, Adrian M. Stütz, Noa Tal, Ifat Geron, Nava Gershman, Shai Izraeli, Juliane Eilers, Nina Vaezipour, Renate Kirschner-Schwabe, Jana Hof, Arend von Stackelberg, Martin Schrappe, Martin Stanulla, Martin Zimmermann, Rolf Koehler, Smadar Avigad, Rupert Handgretinger, Viktoras Frismantas, Jean Pierre Bourquin, Beat Bornhauser, Jan O. Korbel, Martina U. Muckenthaler, Andreas E. Kulozik
Publikováno v:
Haematologica, Vol 99, Iss 10 (2014)
Externí odkaz:
https://doaj.org/article/b89e97b78d674971ac30a7cc3964535a
Autor:
Shabnam Shalapour, Jana Hof, Renate Kirschner-Schwabe, Lorenz Bastian, Cornelia Eckert, Javier Prada, Günter Henze, Arend von Stackelberg, Karl Seeger
Publikováno v:
Haematologica, Vol 96, Iss 11 (2011)
Background Resistance to therapy and subsequent relapse remain major challenges in the clinical management of relapsed childhood acute lymphoblastic leukemia. As the bone marrow environment plays an important role in survival and chemotherapy resista
Externí odkaz:
https://doaj.org/article/5775be6676cf4830b3adacd9197d7532