Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Renate Burger"'
Autor:
Marta Lustig, Christoph Hahn, Marie Leangen Herigstad, Jan Terje Andersen, Jeanette H. W. Leusen, Renate Burger, Thomas Valerius
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Tumor cell phagocytosis by macrophages is considered a relevant mechanism of action for many therapeutic IgG antibodies. However, tumor cells employ several mechanisms to evade immune recognition, including hypersialylation. Here, we describe how red
Externí odkaz:
https://doaj.org/article/da76518ed3c34d60bab02c646afed694
Autor:
Marta Lustig, Chilam Chan, J. H. Marco Jansen, Maria Bräutigam, Max A. Kölling, Carina Lynn Gehlert, Niklas Baumann, Simone Mester, Stian Foss, Jan Terje Andersen, Lorenz Bastian, Peter Sondermann, Matthias Peipp, Renate Burger, Jeanette H. W. Leusen, Thomas Valerius
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Upregulation of surface expressed sialoglycans on tumor cells is one of the mechanisms which promote tumor growth and progression. Specifically, the interactions of sialic acids with sialic acid-binding immunoglobulin-like lectins (Siglecs) on lympho
Externí odkaz:
https://doaj.org/article/f13e63d75bf54d1d864e6a9a22d95511
Autor:
Niklas Baumann, Christian Arndt, Judith Petersen, Marta Lustig, Thies Rösner, Katja Klausz, Christian Kellner, Miriam Bultmann, Lorenz Bastian, Fotini Vogiatzi, Jeanette H. W. Leusen, Renate Burger, Denis M. Schewe, Matthias Peipp, Thomas Valerius
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antibody-based immunotherapy is increasingly employed to treat acute lymphoblastic leukemia (ALL) patients. Many T-ALL cells express CD38 on their surface, which can be targeted by the CD38 antibody daratumumab (DARA), approved for the treatment of m
Externí odkaz:
https://doaj.org/article/aae84b3dbc6245b599a09797f9b180bc
Publikováno v:
Haematologica, Vol 106, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/9cf48112f4f649bcbef298962860da04
Autor:
Stefanie Binder, Nadine Hösler, Diana Riedel, Ivonne Zipfel, Tilo Buschmann, Christoph Kämpf, Kristin Reiche, Renate Burger, Martin Gramatzki, Jörg Hackermüller, Peter F. Stadler, Friedemann Horn
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Interleukin-6 (IL-6)-activated Signal Transducer and Activator of Transcription 3 (STAT3) facilitates survival in the multiple myeloma cell line INA-6 and therefore represents an oncogenic key player. However, the biological mechanisms are s
Externí odkaz:
https://doaj.org/article/b2635f07e4274b1dbd4f152516ba887d
Autor:
Renate Burger, Andreas Günther, Katja Klausz, Matthias Staudinger, Matthias Peipp, Eva Maria Murga Penas, Stefan Rose-John, John Wijdenes, Martin Gramatzki
Publikováno v:
Haematologica, Vol 102, Iss 2 (2017)
Interleukin-6 has an important role in the pathophysiology of multiple myeloma where it supports the growth and survival of the malignant plasma cells in the bone marrow. It belongs to a family of cytokines which use the glycoprotein 130 chain for si
Externí odkaz:
https://doaj.org/article/25cfb90bc325498fbf61fd8803006adb
Autor:
Andreas Günther, Philipp Baumann, Renate Burger, Christian Kellner, Wolfram Klapper, Ralf Schmidmaier, Martin Gramatzki
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
The mammalian target of rapamycin plays an important role in multiple myeloma. The allosteric mammalian target of rapamycin inhibitor everolimus has long been approved for immunosuppression and has shown activity in certain cancers. This investigator
Externí odkaz:
https://doaj.org/article/4bf97507276e41af89184b3dc24b2b11
Autor:
J. H. Marco Jansen, Niklas Baumann, Andreas Humpe, Klara Marie Eichholz, Dorothee Winterberg, Thies Rösner, Jeanette H. W. Leusen, Renate Burger, Chilam Chan, Katja Klausz, Christian Kellner, Matthias Peipp, Denis M. Schewe, Kristina Müller, Thomas Valerius
Publikováno v:
Cancer Science
Integrin associated protein (CD47) is an important target in immunotherapy, as it is expressed as a “don't eat me” signal on many tumor cells. Interference with its counter molecule signal regulatory protein alpha (SIRPα), expressed on myeloid c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4c9d2709e7be9f95728d54dd0059a6
http://europepmc.org/articles/PMC8353920
http://europepmc.org/articles/PMC8353920
Publikováno v:
Haematologica. 106:2507-2510
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4e5d165701ba7d56be538f8b3ff802b
https://doi.org/10.3324/haematol.2020.276865
https://doi.org/10.3324/haematol.2020.276865
Publikováno v:
Forest and Society, Vol 8, Iss 1 (2024)
Mapping the demand for ecosystem services (ES) is a profoundly debated research topic that needs to be investigated further to overcome spatial discrepancies between supply and demand in the literature. This study proposes a holistic approach to valu
Externí odkaz:
https://doaj.org/article/e66cb9507ceb41e8a82dbd2e4d2d8f9f