Výsledky vyhledávání - "Renate Ackermann"

Collagens Serve as an Extracellular Store of Bioactive Interleukin 2

Autor: Nikolaus Tiling, Detlef Schuppan, Renate Ackermann, Martin Ruehl, Rajan Somasundaram, Monika Schmid, Ernst Otto Riecken

Publikováno v: Journal of Biological Chemistry. 275:38170-38175

The binding of certain growth factors and cytokines to components of the extracellular matrix can regulate their local availability and modulate their biological activities. We show that interleukin 2 (IL-2), an important stimulator of T cell growth,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e48cb1c2e39d57c21ea0c73963953d
https://doi.org/10.1074/jbc.m006616200

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Classical proteomics: two-dimensional electrophoresis/MALDI mass spectrometry

Autor: Ursula, Zimny-Arndt, Monika, Schmid, Renate, Ackermann, Peter R, Jungblut

Publikováno v: Methods in molecular biology (Clifton, N.J.). 492

The rapid development in proteomics over the last 10 years has led to a series of new technologies and combinations of them designed to unravel as much as possible of the proteins of an organism or otherwise specified biological material. Despite bei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af9491a9dc70753970021b00dd4eeb53
https://pubmed.ncbi.nlm.nih.gov/19241027

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Undulin, an extracellular matrix glycoprotein associated with collagen fibrils

Autor: J. Becker, M C Cantaluppi, A. Veit, Detlef Schuppan, T. Bunte, F Schuppan, Monika Schmid, D. Troyer, Renate Ackermann, E G Hahn

Publikováno v: Journal of Biological Chemistry. 265:8823-8832

Undulin, a novel noncollagenous extracellular matrix protein, was isolated from skin and placenta. In polyacrylamide gels most of the unreduced protein migrates with Mr above 1,000,000 yielding bands A (Mr 270,000), B1 (Mr 190,000), and B2 (Mr 180,00

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ef947db7feb7613b71c37c8c82921df
https://doi.org/10.1016/s0021-9258(19)38962-8

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Comprehensive quantitative proteome analysis of 20S proteasome subtypes from rat liver by isotope coded affinity tag and 2-D gel-based approaches

Autor: Bernd Thiede, Peter R. Jungblut, Alexander Kloss, Katharina Janek, Frank Schmidt, Renate Ackermann, Burkhardt Dahlmann, Maik A. Wacker

Publikováno v: Proteomics. 6(16)

Quantitative protein profiling is an essential part of proteomics and requires technologies that accurately, reproducibly, and comprehensively identify and quantify proteins. Over the past years, many quantitative proteomic methods have been develope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4493a3409971a1dbfebbdc1a046098
https://pubmed.ncbi.nlm.nih.gov/16858736

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The necessity of functional proteomics: protein species and molecular function elucidation exemplified by in vivo alpha A crystallin N-terminal truncation

Autor: Nalin M. Kumar, Renate Ackermann, Wolfgang Hoehenwarter, Peter R. Jungblut, Ursula Zimny-Arndt

Publikováno v: Amino acids. 31(3)

Ten years after the establishment of the term proteome, the science surrounding it has yet to fulfill its potential. While a host of technologies have generated lists of protein names, there are only a few reported studies that have examined the indi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f70333250064d1715a874db9d6cff41
https://pubmed.ncbi.nlm.nih.gov/16964561

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The epithelial mitogen keratinocyte growth factor binds to collagens via the consensus sequence glycine-proline-hydroxyproline

Autor: Richard W. Farndale, Renate Ackermann, Martin Ruehl, Monika Schmid, C. Graham Knight, Ernst Otto Riecken, Rajan Somasundaram, Detlef Schuppan, Martin Zeitz, Ines Schoenfelder

Publikováno v: The Journal of biological chemistry. 277(30)

The binding of certain growth factors and cytokines to components of the extracellular matrix can regulate their local availability and modulate their biological activities. We show that mesenchymal cell-derived keratinocyte growth factor (KGF), a ke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7aac2b486f3de24518e84988b9955b
https://pubmed.ncbi.nlm.nih.gov/11973338

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Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M

Autor: Martin Zeitz, Detlef Schuppan, Rajan Somasundaram, Monika Schmid, Renate Ackermann, Martin Ruehl, Benjamin Schaefer, Ernst-Otto Riecken

Publikováno v: The Journal of biological chemistry. 277(5)

The binding of certain growth factors and cytokines to components of the extracellular matrix can regulate their local availability and modulate their biological activities. We show that oncostatin M (OSM), a profibrogenic cytokine and modulator of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2bd057dbc81206dcf3d71bd27a8237
https://pubmed.ncbi.nlm.nih.gov/11711546

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Collagens in the liver extracellular matrix bind hepatocyte growth factor

Autor: Renate Ackermann, Martin Ruehl, Rajan Somasundaram, Toshikazu Nakamura, Detlef Schuppan, Monika Schmid, Ernst Otto Riecken

Publikováno v: Gastroenterology. 114(1)

Background & Aims: Hepatocyte growth factor (HGF), a potent mitogen for hepatocytes, binds to heparan sulfate. Because immunoreactive HGF can be detected in the interstitial extracellular matrix (ECM), where little heparan sulfate is found, the aim o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16974fed2f9072a0fc9cacb8533fe332
https://pubmed.ncbi.nlm.nih.gov/9428228

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