Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Renate, Schreiber"'
Autor:
Gudrun Liebscher, Nemanja Vujic, Renate Schreiber, Markus Heine, Caroline Krebiehl, Madalina Duta-Mare, Giorgia Lamberti, Cedric H. de Smet, Michael W. Hess, Thomas O. Eichmann, Sarah Hölzl, Ludger Scheja, Joerg Heeren, Dagmar Kratky, Lukas A. Huber
Publikováno v:
Molecular Metabolism, Vol 71, Iss , Pp 101705- (2023)
Objective: In brown adipose tissue (iBAT), the balance between lipid/glucose uptake and lipolysis is tightly regulated by insulin signaling. Downstream of the insulin receptor, PDK1 and mTORC2 phosphorylate AKT, which activates glucose uptake and lys
Externí odkaz:
https://doaj.org/article/80ac827ee9ab454b8f1e8329b4b25034
Autor:
Isabel Reinisch, Ingeborg Klymiuk, Helene Michenthaler, Elisabeth Moyschewitz, Markus Galhuber, Jelena Krstic, Magnus Domingo, Fangrong Zhang, Michael Karbiener, Nemanja Vujić, Dagmar Kratky, Renate Schreiber, Michael Schupp, Georgia Lenihan-Geels, Tim J. Schulz, Roland Malli, Tobias Madl, Andreas Prokesch
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Active thermogenic adipocytes avidly consume energy substrates like fatty acids and glucose to maintain body temperature upon cold exposure. Despite strong evidence for the involvement of brown adipose tissue (BAT) in controlling systemic energy home
Externí odkaz:
https://doaj.org/article/cca06dc88f894999b651fd41ae8fc777
Autor:
Laura Pajed, Ulrike Taschler, Anna Tilp, Peter Hofer, Petra Kotzbeck, Stephanie Kolleritsch, Franz P. W. Radner, Isabella Pototschnig, Carina Wagner, Margarita Schratter, Sandra Eder, Sabrina Huetter, Renate Schreiber, Guenter Haemmerle, Thomas O. Eichmann, Martina Schweiger, Gerald Hoefler, Erin E. Kershaw, Achim Lass, Gabriele Schoiswohl
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Pajed et al. investigate the role of adipocyte hormone-sensitive lipase (HSL) in whole body energy homeostasis. They show that adipocyte-specific HSL Knockout (AHKO) mice fed high fat diet develop fatty liver. Interestingly, this phenotype reverses i
Externí odkaz:
https://doaj.org/article/489219dde80844a090448c922d5f0fbd
Autor:
Gernot F. Grabner, Nermeen Fawzy, Renate Schreiber, Lisa M. Pusch, Dominik Bulfon, Harald Koefeler, Thomas O. Eichmann, Achim Lass, Martina Schweiger, Gunther Marsche, Gabriele Schoiswohl, Ulrike Taschler, Robert Zimmermann
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 995-1003 (2020)
Bis(monoacylglycero)phosphate (BMP), also known as lysobisphosphatidic acid, is a phospholipid that promotes lipid sorting in late endosomes/lysosomes by activating lipid hydrolases and lipid transfer proteins. Changes in the cellular BMP content the
Externí odkaz:
https://doaj.org/article/2be18605ca1f457e8139b8198ab5f48a
Autor:
Martina Schweiger, Matthias Romauch, Renate Schreiber, Gernot F. Grabner, Sabrina Hütter, Petra Kotzbeck, Pia Benedikt, Thomas O. Eichmann, Sohsuke Yamada, Oskar Knittelfelder, Clemens Diwoky, Carina Doler, Nicole Mayer, Werner De Cecco, Rolf Breinbauer, Robert Zimmermann, Rudolf Zechner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The enzyme Atgl participates in the breakdown of lipids in adipose tissue. Here the authors show that pharmacological inhibition of Atgl reduces weight gain and improves metabolic health in mice fed a high-fat diet, without causing adverse effects in
Externí odkaz:
https://doaj.org/article/6897b936ca4b4463ba1c491fe09495d6
Publikováno v:
Metabolites, Vol 10, Iss 4, p 147 (2020)
The catabolism of intracellular triacylglycerols (TAGs) involves the activity of cytoplasmic and lysosomal enzymes. Cytoplasmic TAG hydrolysis, commonly termed lipolysis, is catalyzed by the sequential action of three major hydrolases, namely adipose
Externí odkaz:
https://doaj.org/article/98c8ef50ed5245528d8b8b348dbaec38
Autor:
Manoja K. Brahma, Rene C. Adam, Nina M. Pollak, Doris Jaeger, Kathrin A. Zierler, Nadja Pöcher, Renate Schreiber, Matthias Romauch, Tarek Moustafa, Sandra Eder, Thomas Ruelicke, Karina Preiss-Landl, Achim Lass, Rudolf Zechner, Guenter Haemmerle
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 11, Pp 2229-2241 (2014)
Fibroblast growth factor 21 (FGF21) is a PPARα-regulated gene elucidated in the liver of PPARα-deficient mice or PPARα agonist-treated mice. Mice globally lacking adipose triglyceride lipase (ATGL) exhibit a marked defect in TG catabolism associat
Externí odkaz:
https://doaj.org/article/70b6f2e8c3c945ada93dc92191f4dc93
Autor:
Gudrun Liebscher, Nemanja Vujic, Renate Schreiber, Markus Heine, Caroline Krebiehl, Madalina Duta-Mare, Giorgia Lamberti, Cedric H. de Smet, Michael W. Hess, Thomas O. Eichmann, Sarah Hölzl, Ludger Scheja, Joerg Heeren, Dagmar Kratky, Lukas A. Huber
In brown adipose tissue (iBAT), the balance of lipid/glucose uptake and lipolysis is regulated by insulin signaling. Downstream of the insulin receptor, PDK1 and mTORC2 phosphorylate AKT, which activates glucose uptake and lysosomal mTORC1 signaling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a65cc593d092426f64ff38eee3b42331
https://doi.org/10.1101/2022.05.17.492242
https://doi.org/10.1101/2022.05.17.492242
Autor:
Renate Schreiber, Rudolf Zechner
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 12, Pp 2447-2449 (2014)
Externí odkaz:
https://doaj.org/article/fb51d40822884aa692023f8aed6cd3d3
Autor:
Nina M. Pollak, Martina Schweiger, Doris Jaeger, Dagmar Kolb, Manju Kumari, Renate Schreiber, Stephanie Kolleritsch, Philipp Markolin, Gernot F. Grabner, Christoph Heier, Kathrin A. Zierler, Thomas Rülicke, Robert Zimmermann, Achim Lass, Rudolf Zechner, Guenter Haemmerle
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 4, Pp 1092-1102 (2013)
Cardiac triacylglycerol (TG) catabolism critically depends on the TG hydrolytic activity of adipose triglyceride lipase (ATGL). Perilipin 5 (Plin5) is expressed in cardiac muscle (CM) and has been shown to interact with ATGL and its coactivator compa
Externí odkaz:
https://doaj.org/article/45f7f200bee54269bc6adf0c8d238cb4