Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Renata Zobalova"'
Autor:
Pankaj Sharma, Elena Maklashina, Markus Voehler, Sona Balintova, Sarka Dvorakova, Michal Kraus, Katerina Hadrava Vanova, Zuzana Nahacka, Renata Zobalova, Stepana Boukalova, Kristyna Cunatova, Tomas Mracek, Hans K. Ghayee, Karel Pacak, Jakub Rohlena, Jiri Neuzil, Gary Cecchini, T. M. Iverson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Complex II (CII) activity controls phenomena that require crosstalk between metabolism and signaling, including neurodegeneration, cancer metabolism, immune activation, and ischemia-reperfusion injury. CII activity can be regulated at the le
Externí odkaz:
https://doaj.org/article/a63f5096183a4241a866d4154beb8b16
Autor:
Zuzana Bielcikova, Jan Stursa, Ludmila Krizova, Lanfeng Dong, Jan Spacek, Stanislav Hlousek, Michal Vocka, Katerina Rohlenova, Olga Bartosova, Vladimir Cerny, Tomas Padrta, Michal Pesta, Pavel Michalek, Sona Stemberkova Hubackova, Katarina Kolostova, Eliska Pospisilova, Vladimir Bobek, Peter Klezl, Renata Zobalova, Berwini Endaya, Jakub Rohlena, Lubos Petruzelka, Lukas Werner, Jiri Neuzil
Publikováno v:
EClinicalMedicine, Vol 57, Iss , Pp 101873- (2023)
Summary: Background: Mitochondria present an emerging target for cancer treatment. We have investigated the effect of mitochondrially targeted tamoxifen (MitoTam), a first-in-class anti-cancer agent, in patients with solid metastatic tumours. Methods
Externí odkaz:
https://doaj.org/article/91ab15755d5b4f4c9326f015bc30ba5c
Autor:
Jindriska Leischner Fialova, Katerina Hönigova, Martina Raudenska, Lucie Miksatkova, Renata Zobalova, Jiri Navratil, Jana Šmigová, Taraka Ramji Moturu, Tomas Vicar, Jan Balvan, Katerina Vesela, Nikita Abramenko, Zdenek Kejik, Robert Kaplanek, Jaromir Gumulec, Daniel Rosel, Pavel Martasek, Jan Brábek, Milan Jakubek, Jiri Neuzil, Michal Masarik
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113582- (2022)
Mitochondria generate energy and building blocks required for cellular growth and function. The notion that mitochondria are not involved in the cancer growth has been challenged in recent years together with the emerging idea of mitochondria as a pr
Externí odkaz:
https://doaj.org/article/80b69231f27345709bd67e8a884e9d4a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Mitochondria are organelles essential for tumor cell proliferation and metastasis. Although their main cellular function, generation of energy in the form of ATP is dispensable for cancer cells, their capability to drive their adaptation to stress or
Externí odkaz:
https://doaj.org/article/1235d0dc2976444aa89950ddcd6085cb
Autor:
Sona Stemberkova‐Hubackova, Renata Zobalova, Maria Dubisova, Jana Smigova, Sarka Dvorakova, Klara Korinkova, Zuzana Ezrova, Berwini Endaya, Kristyna Blazkova, Erik Vlcak, Petra Brisudova, Dan‐Diem Thi Le, Stefan Juhas, Daniel Rosel, Cristina Daniela Kelemen, Dana Sovilj, Eliska Vacurova, Tomas Cajka, Vlada Filimonenko, Lanfeng Dong, Ladislav Andera, Pavel Hozak, Jan Brabek, Zuzana Bielcikova, Jan Stursa, Lukas Werner, Jiri Neuzil
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 3, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/6ffa7e718404400f926a4f1d5c918cd7
Autor:
Ayenachew Bezawork-Geleta, He Wen, LanFeng Dong, Bing Yan, Jelena Vider, Stepana Boukalova, Linda Krobova, Katerina Vanova, Renata Zobalova, Margarita Sobol, Pavel Hozak, Silvia Magalhaes Novais, Veronika Caisova, Pavel Abaffy, Ravindra Naraine, Ying Pang, Thiri Zaw, Ping Zhang, Radek Sindelka, Mikael Kubista, Steven Zuryn, Mark P. Molloy, Michael V. Berridge, Karel Pacak, Jakub Rohlena, Sunghyouk Park, Jiri Neuzil
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Mitochondrial complex II is normally composed of four subunits. Here the authors show that bioenergetic stress conditions give rise to a partially assembled variant of complex II, which shifts the anabolic pathways to less energy demanding processes.
Externí odkaz:
https://doaj.org/article/762a6e8dd0c245dd8c980ced8121b927
Autor:
Elham Alizadeh Pasdar, Michael Smits, Michael Stapelberg, Martina Bajzikova, Marina Stantic, Jacob Goodwin, Bing Yan, Jan Stursa, Jaromira Kovarova, Karishma Sachaphibulkij, Ayenachew Bezawork-Geleta, Margaryta Sobol, Anatoly Filimonenko, Marco Tomasetti, Renata Zobalova, Pavel Hozak, Lan-Feng Dong, Jiri Neuzil
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156012 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0119549.].
Externí odkaz:
https://doaj.org/article/a8bf72d4bf63430498757f9ffef1f6e6
Autor:
Elham Alizadeh Pasdar, Michael Smits, Michael Stapelberg, Martina Bajzikova, Marina Stantic, Jacob Goodwin, Bing Yan, Jan Stursa, Jaromira Kovarova, Karishma Sachaphibulkij, Ayenachew Bezawork-Geleta, Margaryta Sobol, Anatoly Filimonenko, Marco Tomasetti, Renata Zobalova, Pavel Hozak, Lan-Feng Dong, Jiri Neuzil
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0119549 (2015)
Malignant mesothelioma (MM) is an aggressive type of tumour causing high mortality. One reason for this paradigm may be the existence of a subpopulation of tumour-initiating cells (TICs) that endow MM with drug resistance and recurrence. The objectiv
Externí odkaz:
https://doaj.org/article/a785e430df50486c96bc071f5315b30c
Autor:
Lan-Feng Dong, Jakub Rohlena, Renata Zobalova, Zuzana Nahacka, Anne-Marie Rodriguez, Michael V. Berridge, Jiri Neuzil
Publikováno v:
Journal of Cell Biology. 222
Mammalian genes were long thought to be constrained within somatic cells in most cell types. This concept was challenged recently when cellular organelles including mitochondria were shown to move between mammalian cells in culture via cytoplasmic br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55510d81d680da6acb4bd5fca780dddd
https://doi.org/10.1083/jcb.202211044
https://doi.org/10.1083/jcb.202211044
Autor:
Pankaj Sharma, Elena Maklashina, Markus Voehler, Sona Balintova, Sarka Dvorakova, Michal Kraus, Katerina Hadrava Vanova, Zuzana Nahacka, Renata Zobalova, Stepana Boukalova, Tomas Mracek, Hans Ghayee, Karel Pacak, Jakub Rohlena, Jiri Neuzil, Gary Cecchini, T Iverson
Mitochondrial Complex II (CII) activity supports multiple types of respiration and connects metabolic state with succinate signaling. It is therefore unsurprising that CII activity has been linked to biological phenomena that require crosstalk betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daef871ae2d1f27caba9813786c90e52
https://doi.org/10.21203/rs.3.rs-2070392/v1
https://doi.org/10.21203/rs.3.rs-2070392/v1
