Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Renata Z. Jurkowska"'
Autor:
Marija Đorđević, Peter Stepper, Clarissa Feuerstein-Akgoz, Clarissa Gerhauser, Verica Paunović, Anja Tolić, Jovana Rajić, Svetlana Dinić, Aleksandra Uskoković, Nevena Grdović, Mirjana Mihailović, Renata Z. Jurkowska, Tomasz P. Jurkowski, Jelena Arambašić Jovanović, Melita Vidaković
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionBeta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presence of polyhormonal cells are main characteristics of diabetes. The straightforward strategy for curing diabetes implies reestablishment of pancreatic be
Externí odkaz:
https://doaj.org/article/366d6c80f48f4fac8cb7a3ddf9cb8ff4
Autor:
Linfeng Gao, Max Emperle, Yiran Guo, Sara A. Grimm, Wendan Ren, Sabrina Adam, Hidetaka Uryu, Zhi-Min Zhang, Dongliang Chen, Jiekai Yin, Michael Dukatz, Hiwot Anteneh, Renata Z. Jurkowska, Jiuwei Lu, Yinsheng Wang, Pavel Bashtrykov, Paul A. Wade, Gang Greg Wang, Albert Jeltsch, Jikui Song
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
In mammals, DNA methylation patterns are established by two de novo DNA methyltransferases, DNMT3A and DNMT3B. Here the authors report the crystal structures of DNMT3B in complex with both CpG and CpA DNA, providing insight into the substrate-recogni
Externí odkaz:
https://doaj.org/article/effe2dab19bf4176b1b1739202fca190
Autor:
Maria Llamazares-Prada, Elisa Espinet, Vedrana Mijošek, Uwe Schwartz, Pavlo Lutsik, Raluca Tamas, Mandy Richter, Annika Behrendt, Stephanie T. Pohl, Naja P. Benz, Thomas Muley, Arne Warth, Claus Peter Heußel, Hauke Winter, Jonathan J. M. Landry, Felix J.F. Herth, Tinne C.J. Mertens, Harry Karmouty-Quintana, Ina Koch, Vladimir Benes, Jan O. Korbel, Sebastian M. Waszak, Andreas Trumpp, David M. Wyatt, Heiko F. Stahl, Christoph Plass, Renata Z. Jurkowska
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
Complexity of lung microenvironment and changes in cellular composition during disease make it exceptionally hard to understand molecular mechanisms driving development of chronic lung diseases. Although recent advances in cell type–resolved approa
Externí odkaz:
https://doaj.org/article/4b9ddf2689b3451391994aacacc3f941
Autor:
Renata Z. Jurkowska, Su Qin, Goran Kungulovski, Wolfram Tempel, Yanli Liu, Pavel Bashtrykov, Judith Stiefelmaier, Tomasz P. Jurkowski, Srikanth Kudithipudi, Sara Weirich, Raluca Tamas, Hong Wu, Ludmila Dombrovski, Peter Loppnau, Richard Reinhardt, Jinrong Min, Albert Jeltsch
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
SETDB1 is a histone methyltransferase that generates H3K9me3 marks in euchromatic regions. Here the authors show that the triple Tudor domain (3TD) of SETDB1 binds histone H3 tails containing K14 acetylation combined with K9 methylation, and that the
Externí odkaz:
https://doaj.org/article/359b9add32a74c369b6c1bb36155be12
Autor:
Uwe Schwartz, Maria Llamazares Prada, Stephanie T Pohl, Mandy Richter, Raluca Tamas, Michael Schuler, Corinna Keller, Vedrana Mijosek, Thomas Muley, Marc A Schneider, Karsten Quast, Joschka Hey, Claus P Heußel, Arne Warth, Hauke Winter, Özdemirhan Serçin, Harry Karmouty‐Quintana, Soma SK Jyothula, Manish K Patel, Felix Herth, Ina Koch, Giuseppe Petrosino, Alexandru Titimeaua, Balca R Mardin, Dieter Weichenhan, Tomasz P Jurkowski, Charles D Imbusch, Benedikt Brors, Vladimir Benes, Birgit Jung, David Wyatt, Heiko F Stahl, Christoph Plass, Renata Z Jurkowska
Publikováno v:
The EMBO Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::add00c93d6e45af914fbf764adb11af1
https://doi.org/10.15252/embj.2022111272
https://doi.org/10.15252/embj.2022111272
Autor:
Renata Z, Jurkowska, Albert, Jeltsch
Publikováno v:
Advances in experimental medicine and biology. 1389
DNA methylation is a hot topic in basic and biomedical research. Despite tremendous progress in understanding the structures and biochemical properties of the mammalian DNA methyltransferases (DNMTs), principles of their targeting and regulation in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e0b57b7656cf20aa29746436b4833653
https://pubmed.ncbi.nlm.nih.gov/36350507
https://pubmed.ncbi.nlm.nih.gov/36350507
Autor:
Renata Z, Jurkowska, Albert, Jeltsch
Publikováno v:
Advances in experimental medicine and biology. 1389
DNA methylation and DNA methyltransferases (MTases)-the enzymes that introduce the methylation mark into the DNA-have been studied for almost 70 years. In this chapter, we review the key developments in the DNA methylation field that have led to our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4a58e5961274059ff10e180228718c51
https://pubmed.ncbi.nlm.nih.gov/36350504
https://pubmed.ncbi.nlm.nih.gov/36350504
Autor:
Mirunalini Ravichandran, Dominik Rafalski, Claudia I. Davies, Oscar Ortega-Recalde, Xinsheng Nan, Cassandra R. Glanfield, Annika Kotter, Katarzyna Misztal, Andrew H. Wang, Marek Wojciechowski, Michał Rażew, Issam M. Mayyas, Olga Kardailsky, Uwe Schwartz, Krzysztof Zembrzycki, Ian M. Morison, Mark Helm, Dieter Weichenhan, Renata Z. Jurkowska, Felix Krueger, Christoph Plass, Martin Zacharias, Matthias Bochtler, Timothy A. Hore, Tomasz P. Jurkowski
Publikováno v:
Science advances 8(36), eabm2427 (2022). doi:10.1126/sciadv.abm2427
Science advances 8(36), eabm2427 (2022). doi:10.1126/sciadv.abm2427
TET (ten-eleven translocation) enzymes catalyze the oxidation of 5-methylcytosine bases in DNA, thus driving active and passive DNA demethylation. Here, we report that the catal
TET (ten-eleven translocation) enzymes catalyze the oxidation of 5-methylcytosine bases in DNA, thus driving active and passive DNA demethylation. Here, we report that the catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6e2ca3b8587f963c190ffc3435d85e
https://orca.cardiff.ac.uk/id/eprint/152480/1/sciadv.abm2427.pdf
https://orca.cardiff.ac.uk/id/eprint/152480/1/sciadv.abm2427.pdf
Autor:
Uwe Schwartz, Maria Llamazares Prada, Stephanie T. Pohl, Mandy Richter, Raluca Tamas, Michael Schuler, Corinna Keller, Vedrana Mijosek, Thomas Muley, Marc A. Schneider, Karsten Quast, Joschka Hey, Claus P. Heußel, Arne Warth, Hauke Winter, Özdemirhan Serçin, Harry Karmouty-Quintana, Felix Herth, Ina Koch, Giuseppe Petrosino, Balca R. Mardin, Dieter Weichenhan, Tomasz P. Jurkowski, Charles D. Imbusch, Benedikt Brors, Vladimir Benes, Brigit Jung, David Wyatt, Heiko Stahl, Christoph Plass, Renata Z. Jurkowska
Patients with chronic obstructive pulmonary disease (COPD) are still waiting for curative treatments. Considering the environmental cause of COPD (e.g., cigarette smoke) and disease phenotypes, including stem-cell senescence and impaired differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85bd90abe91fb9904d07649ca3115e87
https://doi.org/10.1101/2022.03.28.486023
https://doi.org/10.1101/2022.03.28.486023
Autor:
Renata Z. Jurkowska, Albert Jeltsch
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031114533
Advances in Experimental Medicine and Biology ISBN: 9783319436227
Advances in Experimental Medicine and Biology ISBN: 9783319436227
DNA methylation and DNA methyltransferases (MTases) – the enzymes that introduce the methylation mark into the DNA – have been studied for almost 70 years. In this chapter, we review key developments in the field that led to our current understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0972150d1241af95b4759ea7b52ed1de
https://doi.org/10.1007/978-3-031-11454-0_1
https://doi.org/10.1007/978-3-031-11454-0_1