Aliskiren and l-arginine treatments restore depressed baroreflex sensitivity and decrease oxidative stress in renovascular hypertension rats

Autor: Simone Alves de Almeida, Cíntia Helena Santuzzi, Renata Tiradentes, Sonia Alves Gouvea, Paulo Hm Silva, Vinicius Mengal, Gabriela C. Sena, Gláucia R. Abreu, Nazaré Souza Bissoli

Publikováno v: Hypertension Research. 39:769-776

Renovascular hypertension is characterized by increased angiotensin II and oxidative stress, and by endothelial dysfunction. The purpose of this study was to test whether the administration of aliskiren (ALSK) and l-arginine (l-ARG) would restore imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823a5e2af3986b65adaca147ac58702b
https://doi.org/10.1038/hr.2016.61

Swimming training prevents coronary endothelial dysfunction in ovariectomized spontaneously hypertensive rats

Autor: Nazaré Souza Bissoli, Cíntia Helena Santuzzi, Vinicius Mengal, Erick Roberto Gonçalves Claudio, Simone Alves de Almeida, Gláucia R. Abreu, Renata Tiradentes, Sonia Alves Gouvea, Roger Lyrio dos Santos, Girlandia Alexandre Brasil

Publikováno v: Brazilian Journal of Medical and Biological Research, Volume: 50, Issue: 1, Article number: e5495, Published: 16 JAN 2017
Brazilian Journal of Medical and Biological Research v.50 n.1 2017
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Vol 50, Iss 1

Estrogen deficiency and hypertension are considered major risk factors for the development of coronary heart disease. On the other hand, exercise training is considered an effective form to prevent and treat cardiovascular diseases. However, the effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7892d0e61d3d8bf4df28314ca0fbc1f5
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000100607&lng=en&tlng=en

Evidence that Combined Aliskiren and L‐arginine Treatment Reverses Renovascular Hypertension in an Animal Model

Autor: Renata Tiradentes, Cíntia Helena Santuzzi, Sonia Alves Gouvea, Henrique A. Futuro-Neto, Vinicius Mengal, Gláucia R. Abreu, Nyam da Silva

Publikováno v: The FASEB Journal. 29

Renovascular hypertension is characterized by increased renal sympathetic activity, angiotensin II, and by endothelial dysfunction. The purpose of this study was to determine the role of renal symp...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::379b4c5934f0e500862b359cbab59e65
https://doi.org/10.1096/fasebj.29.1_supplement.812.1

Combined aliskiren and L-arginine treatment has antihypertensive effects and prevents vascular endothelial dysfunction in a model of renovascular hypertension

Autor: Cíntia Helena Santuzzi, Renata Tiradentes, Erick Roberto Gonçalves Claudio, Vinicius Mengal, Sonia Alves Gouvea, Helder Mauad, Gláucia R. Abreu

Publikováno v: Brazilian Journal of Medical and Biological Research, Volume: 48, Issue: 1, Pages: 65-76, Published: 24 OCT 2014
Brazilian Journal of Medical and Biological Research v.48 n.1 2015
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Vol 48, Iss 1, Pp 65-76 (2014)
Brazilian Journal of Medical and Biological Research, Vol 48, Iss 1, Pp 65-76 (2015)

Angiotensin II is a key player in the pathogenesis of renovascular hypertension, a condition associated with endothelial dysfunction. We investigated aliskiren (ALSK) and L-arginine treatment both alone and in combination on blood pressure (BP), and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb35601ddf2739b1e03fd39fd58aa7c
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000100065&lng=en&tlng=en

Effects of treatment with aliskiren and l ‐arginine in baroreflex sensitivity in renovascular hypertensive rats (856.5)

Autor: Paulo Hm Silva, Vinicius Mengal, Cíntia Helena Santuzzi, Gláucia R. Abreu, Renata Tiradentes, Sonia Alves Gouvea

Publikováno v: The FASEB Journal. 28

In some pathological conditions such as hypertension, there is an impairment in the autonomic control of blood pressure resulting in changes in baroreflex sensitivity. In this context, this work aims to elucidate the benefits of the combination of al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64e389fb264906fe837615defe34ef50
https://doi.org/10.1096/fasebj.28.1_supplement.856.5