Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Renata Sigrist"'
Autor:
Bruna Domingues Vieira, Henrique Niero, Rafael de Felício, Luiz Fernando Giolo Alves, Cristina Freitas Bazzano, Renata Sigrist, Luciana Costa Furtado, Gabriela Felix Persinoti, Leticia Veras Costa-Lotufo, Daniela Barretto Barbosa Trivella
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Streptomyces sp. BRA-346 is an Actinobacteria isolated from the Brazilian endemic tunicate Euherdmania sp. We have reported that this strain produces epoxyketone peptides, as dihydroeponemycin (DHE) and structurally related analogs. This cocktail of
Externí odkaz:
https://doaj.org/article/61a5956fa2dc49d9ab7ae42ab531b604
Autor:
Rafael de Felício, Patricia Ballone, Cristina Freitas Bazzano, Luiz F. G. Alves, Renata Sigrist, Gina Polo Infante, Henrique Niero, Fernanda Rodrigues-Costa, Arthur Zanetti Nunes Fernandes, Luciane A. C. Tonon, Luciana S. Paradela, Renna Karoline Eloi Costa, Sandra Martha Gomes Dias, Andréa Dessen, Guilherme P. Telles, Marcus Adonai Castro da Silva, Andre Oliveira de Souza Lima, Daniela Barretto Barbosa Trivella
Publikováno v:
Metabolites, Vol 11, Iss 2, p 107 (2021)
Bacterial genome sequencing has revealed a vast number of novel biosynthetic gene clusters (BGC) with potential to produce bioactive natural products. However, the biosynthesis of secondary metabolites by bacteria is often silenced under laboratory c
Externí odkaz:
https://doaj.org/article/01eb09cf4a654fd6b25e0e34cec1edf8
Publikováno v:
Química Nova, Vol 42, Iss 1, Pp 71-83
Natural products continue to inspire scientists on the search for biological active structures. Recent advances in synthetic biology allow modifying genes to extend structural diversity present on natural products by changing important functional gro
Externí odkaz:
https://doaj.org/article/61977b9462aa4e79a58b51c1893d1094
Autor:
Christopher M. Whitford, Peter Gockel, David Faurdal, Tetiana Gren, Renata Sigrist, Tilmann Weber
Type I CRISPR systems are widespread in bacteria and archaea. The main differences compared to more widely applied type II systems are multi-effector CASCADE needed for crRNA processing and target recognition, as well as the processive nature of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07318b628f574799016657597675a81d
https://doi.org/10.1101/2023.05.09.539971
https://doi.org/10.1101/2023.05.09.539971
Autor:
Bruna, Domingues Vieira, Henrique, Niero, Rafael, de Felício, Luiz Fernando, Giolo Alves, Cristina, Freitas Bazzano, Renata, Sigrist, Luciana, Costa Furtado, Gabriela, Felix Persinoti, Leticia, Veras Costa-Lotufo, Daniela, Barretto Barbosa Trivella
Publikováno v:
Frontiers in microbiology. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aab8515513cf6362c9eb7f169ec458b6
https://pubmed.ncbi.nlm.nih.gov/35401454
https://pubmed.ncbi.nlm.nih.gov/35401454
Publikováno v:
ChemistrySelect. 4:7785-7790
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ba2b53648515e0c33ec4aad703af290
https://doi.org/10.1002/slct.201900922
https://doi.org/10.1002/slct.201900922
Publikováno v:
Angew Chem Int Ed Engl
l-4-Chlorokynurenine (l-4-Cl-Kyn) is a neuropharmaceutical drug candidate that is in development for the treatment of major depressive disorder. Recently, this amino acid was naturally found as a residue in the lipopeptide antibiotic taromycin. Herei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25617772f07159cfc18605184faf0595
https://doi.org/10.1002/anie.201901571
https://doi.org/10.1002/anie.201901571
Autor:
Sandra M. G. Dias, Luiz F. G. Alves, Gina Polo Infante, Fernanda Rodrigues-Costa, Renna Karoline Eloi Costa, Cristina Freitas Bazzano, Arthur Zanetti Nunes Fernandes, Luciana S. Paradela, Renata Sigrist, Guilherme P. Telles, André Oliveira de Souza Lima, Rafael de Felício, Marcus Adonai Castro da Silva, Luciane Alessandra Chimetto Tonon, Daniela B. B. Trivella, Patricia Ballone, Henrique Niero, Andréa Dessen
Publikováno v:
Metabolites
Metabolites, 2021, 11 (2), pp.107. ⟨10.3390/metabo11020107⟩
Metabolites, MDPI, 2021, 11 (2), pp.107. ⟨10.3390/metabo11020107⟩
Metabolites; Volume 11; Issue 2; Pages: 107
Metabolites, Vol 11, Iss 107, p 107 (2021)
Metabolites, 2021, 11 (2), pp.107. ⟨10.3390/metabo11020107⟩
Metabolites, MDPI, 2021, 11 (2), pp.107. ⟨10.3390/metabo11020107⟩
Metabolites; Volume 11; Issue 2; Pages: 107
Metabolites, Vol 11, Iss 107, p 107 (2021)
International audience; Bacterial genome sequencing has revealed a vast number of novel biosynthetic gene clusters (BGC) with potential to produce bioactive natural products. However, the biosynthesis of secondary metabolites by bacteria is often sil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63216574a7ed212445ca764e031d707f
http://europepmc.org/articles/PMC7918856
http://europepmc.org/articles/PMC7918856
Autor:
Amanda F. da Silva, Luciana G. de Oliveira, Renata Sigrist, Shaun M. K. McKinnie, Igor D. Jurberg, Hanna Luhavaya, Bradley S. Moore
Publikováno v:
ACS chemical biology, vol 15, iss 4
ACS Chem Biol
ACS Chem Biol
Alpiniamide A is a linear polyketide produced by Streptomyces endophytic bacteria. Despite its relatively simple chemical structure suggestive of a linear assembly line biosynthetic construction involving a hybrid polyketide synthase-nonribosomal pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fd6e99d06928441f0a844dea7f7888
https://escholarship.org/uc/item/239811fx
https://escholarship.org/uc/item/239811fx
Publikováno v:
Journal of Visualized Experiments.
The chemical space covered by natural products is immense and widely unrecognized. Therefore, convenient methodologies to perform wide-ranging evaluation of their functions in nature and potential human benefits (e.g., for drug discovery applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919c0fb64a971f1fc73c3671974cbbcf
https://doi.org/10.3791/60825-v
https://doi.org/10.3791/60825-v