The Novel Leptospiral Surface Adhesin Lsa20 Binds Laminin and Human Plasminogen and Is Probably Expressed during Infection

Autor: Amane Paldês Gonçales, Marina V. Atzingen, Zenaide Maria de Morais, Silvio Arruda Vasconcellos, Eliete Caló Romero, Ana L. T. O. Nascimento, Amanda F. Asega, Solange M.T. Serrano, Renata S. Mendes

Publikováno v: Infection and Immunity. 79:4657-4667

Leptospirosis is an emerging infectious disease caused by pathogenic species of Leptospira . In this work, we report the cloning, expression, purification, and characterization of two predicted leptospiral outer membrane proteins, LIC11469 and LIC110

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc4b24a6b6ea057212588f913d09245
https://doi.org/10.1128/iai.05583-11

Plasminogen Binding Proteins and Plasmin Generation on the Surface of Leptospira spp.: The Contribution to the Bacteria-Host Interactions

Autor: Marina V. Atzingen, Monica L. Vieira, Rosane Oliveira, Silvio Arruda Vasconcellos, Ana L. T. O. Nascimento, Renata S. Mendes, Renan F. Domingos

Publikováno v: Journal of Biomedicine and Biotechnology, Vol 2012 (2012)
Journal of Biomedicine and Biotechnology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Leptospirosis is considered a neglected infectious disease of human and veterinary concern. Although extensive investigations on host-pathogen interactions have been pursued by several research groups, mechanisms of infection, invasion and persistenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db649c7d2e7b9d5e558555118bab5cc
https://doaj.org/article/95129a44dae64ccc851e1fdf0425a7aa