Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Renata Pellegrino da Silva"'
Autor:
Samantha N Weiss, Joseph M Legato, Yichuan Liu, Courtney N Vaccaro, Renata Pellegrino Da Silva, Sandra Miskiel, Grace V Gilbert, Hakon Hakonarson, David A Fuller, Russell J Buono
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0304773 (2024)
Application of polyethylene glycol (PEG) to a peripheral nerve injury at the time of primary neurorrhaphy is thought to prevent Wallerian degeneration via direct axolemma fusion. The molecular mechanisms of nerve fusion and recovery are unclear. Our
Externí odkaz:
https://doaj.org/article/f38d0b7bb1a64951a1a44eb979239621
Autor:
Mahsa Servati, Courtney N. Vaccaro, Emily E. Diller, Renata Pellegrino Da Silva, Fernanda Mafra, Sha Cao, Katherine B. Stanley, Aaron A. Cohen-Gadol, Jason G. Parker
Publikováno v:
Metabolites, Vol 14, Iss 6, p 337 (2024)
Intratumoral heterogeneity (ITH) complicates the diagnosis and treatment of glioma, partly due to the diverse metabolic profiles driven by underlying genomic alterations. While multiparametric imaging enhances the characterization of ITH by capturing
Externí odkaz:
https://doaj.org/article/9075b82c4ff24b3d870b42e7936a4fd4
Autor:
Alanna Strong, Meckenzie Behr, Carina Lott, Abigail J. Clark, Frank Mentch, Renata Pellegrino Da Silva, Danielle R. Rux, Robert Campbell, Cara Skraban, Xiang Wang, Jason B. Anari, Benjamin Sinder, Patrick J. Cahill, Patrick Sleiman, Hakon Hakonarson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Thoracic insufficiency syndromes are a genetically and phenotypically heterogeneous group of disorders characterized by congenital abnormalities or progressive deformation of the chest wall and/or vertebrae that result in restrictive lung di
Externí odkaz:
https://doaj.org/article/822bda9121314ca48efff01330f63e08
Autor:
Li Fang, Charlly Kao, Michael V. Gonzalez, Fernanda A. Mafra, Renata Pellegrino da Silva, Mingyao Li, Sören-Sebastian Wenzel, Katharina Wimmer, Hakon Hakonarson, Kai Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Compared to single nucleotide variants and short indels, structural variants (SVs) are often more challenging to detect using high-throughput sequencing based methods. Here, the authors develop LinkedSV, a computational tool for SV detection using li
Externí odkaz:
https://doaj.org/article/76f9da9e0bae457b92757a7d2b1f0be4
Autor:
Prasanna M Chandramouleeswaran, Manti Guha, Masataka Shimonosono, Kelly A Whelan, Hisatsugu Maekawa, Uma M Sachdeva, Gordon Ruthel, Sarmistha Mukherjee, Noah Engel, Michael V Gonzalez, James Garifallou, Shinya Ohashi, Andres J Klein-Szanto, Clementina A Mesaros, Ian A Blair, Renata Pellegrino da Silva, Hakon Hakonarson, Eishi Noguchi, Joseph A Baur, Hiroshi Nakagawa
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239625 (2020)
During alcohol consumption, the esophageal mucosa is directly exposed to high concentrations of ethanol (EtOH). We therefore investigated the response of normal human esophageal epithelial cell lines EPC1, EPC2 and EPC3 to acute EtOH exposure. While
Externí odkaz:
https://doaj.org/article/5a4df4b8798b4fd795ef2f8d80b295c8
Autor:
Nori Matsunami, Dexter Hadley, Charles H Hensel, G Bryce Christensen, Cecilia Kim, Edward Frackelton, Kelly Thomas, Renata Pellegrino da Silva, Jeff Stevens, Lisa Baird, Brith Otterud, Karen Ho, Tena Varvil, Tami Leppert, Christophe G Lambert, Mark Leppert, Hakon Hakonarson
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52239 (2013)
Structural variation is thought to play a major etiological role in the development of autism spectrum disorders (ASDs), and numerous studies documenting the relevance of copy number variants (CNVs) in ASD have been published since 2006. To determine
Externí odkaz:
https://doaj.org/article/8f019b4696504a81b6489786168f61ab
Autor:
Lutian Yao, Danielle Rux, Ling Qin, Marco Angelozzi, Ranjan Kc, Renata Pellegrino da Silva, Abdul Haseeb, Véronique Lefebvre, Robert J. Tower, Maurizio Pacifici, Charles de Charleroy
Publikováno v:
Yearbook of Paediatric Endocrinology.
Cartilage is essential throughout vertebrate life. It starts developing in embryos when osteochondroprogenitor cells commit to chondrogenesis, activate a pancartilaginous program to form cartilaginous skeletal primordia, and also embrace a growth-pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb0837b00ef95b34757a6b5039e88da
https://doi.org/10.1530/ey.18.5.13
https://doi.org/10.1530/ey.18.5.13
Autor:
Sören-Sebastian Wenzel, Kai Wang, Katharina Wimmer, Li Fang, Renata Pellegrino da Silva, Charlly Kao, Hakon Hakonarson, Fernanda Abani Mafra, Mingyao Li, Michael Gonzalez
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
Linked-read sequencing provides long-range information on short-read sequencing data by barcoding reads originating from the same DNA molecule, and can improve detection and breakpoint identification for structural variants (SVs). Here we present Lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237a5d5be29186db05820aece0a467e7
http://link.springer.com/article/10.1038/s41467-019-13397-7
http://link.springer.com/article/10.1038/s41467-019-13397-7
Autor:
Maurício Scopel Hoffmann, Marcos L. Santoro, Rodrigo A. Bressan, Marcelo Q. Hoexter, Hakon Hakonarson, Rodrigo Grassi-Oliveira, Renata Pellegrino da Silva, Daniel S. Pine, André Zugman, Pedro Mario Pan, André Rafael Simioni, Sintia Iole Belangero, Edson Amaro Junior, Fernanda Talarico, Ary Gadelha, Salvador M. Guinjoan, Luiza Kvitko Axelrud, Elisa Brietzke, Euripedes Constantino Miguel, João Ricardo Sato, Luis Augusto Rohde, Giovanni Abrahão Salum
Publikováno v:
Neurobiol Aging
Research suggested accumulation of tau proteins might lead to the degeneration of functional networks. Studies investigating the impact of genetic risk for Alzheimer's disease (AD) on early brain connections might shed light on mechanisms leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0210abf4a165beb6d8738860943b0e
https://doi.org/10.1016/j.neurobiolaging.2019.06.011
https://doi.org/10.1016/j.neurobiolaging.2019.06.011
Publikováno v:
Cell Reports. 40:111045
The mammalian skull vault is essential to shape the head and protect the brain, but the cellular and molecular events underlying its development remain incompletely understood. Single-cell transcriptomic profiling from early to late mouse embryonic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bf07c05feb136afdc3522e2d811d12
https://doi.org/10.1016/j.celrep.2022.111045
https://doi.org/10.1016/j.celrep.2022.111045