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pro vyhledávání: '"Renata Murgasva"'
Autor:
Zheng Huang, Lei Zhang, Liette Belair, Wayne Sturkenboom, Chun Sing Li, Yeeman K. Ramtohul, Jocelyne Guay, Renata Murgasva
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5214-5217
SCD1 inhibition may represent a novel treatment for obesity, type-2 diabetes and related metabolic disorders. A prototype thiazole amide analog 13 (MF-152) was identified as an excellent tool in the study of SCD biology in animals.