Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Renata Mangione"'
Autor:
Martin Wohlwend, Pirkka-Pekka Laurila, Ludger JE Goeminne, Tanes Imamura de lima, Ioanna Daskalaki, Xiaoxu Li, Giacomo von Alvensleben, Barbara Crisol, Renata Mangione, Hector Gallart-Ayala, Amelia Lalou, Olivier Burri, Stephen Butler, Jonathan C Morris, Nigel Turner, Julijana Ivanisevic, Johan Auwerx
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/c54b2c68b1ee4416b63703caea4ade82
Autor:
Martin Wohlwend, Pirkka-Pekka Laurila, Ludger JE Goeminne, Tanes Lima, Ioanna Daskalaki, Xiaoxu Li, Giacomo von Alvensleben, Barbara Crisol, Renata Mangione, Hector Gallart-Ayala, Amélia Lalou, Olivier Burri, Stephen Butler, Jonathan Morris, Nigel Turner, Julijana Ivanisevic, Johan Auwerx
Publikováno v:
eLife, Vol 12 (2024)
Age-related muscle wasting and dysfunction render the elderly population vulnerable and incapacitated, while underlying mechanisms are poorly understood. Here, we implicate the CERS1 enzyme of the de novo sphingolipid synthesis pathway in the pathoge
Externí odkaz:
https://doaj.org/article/d20d88bab189434da372a5ca93b464e3
Autor:
Fabio Ciccarone, Serena Castelli, Giacomo Lazzarino, Silvia Scaricamazza, Renata Mangione, Sergio Bernardini, Savina Apolloni, Nadia D'Ambrosi, Alberto Ferri, Maria Rosa Ciriolo
Publikováno v:
Genes and Diseases, Vol 10, Iss 2, Pp 321-324 (2023)
Externí odkaz:
https://doaj.org/article/2b09185f3444481ea03029995ffee618
Autor:
Renata Mangione, Cesarina Giallongo, Andrea Duminuco, Enrico La Spina, Lucia Longhitano, Sebastiano Giallongo, Daniele Tibullo, Giuseppe Lazzarino, Miriam Wissam Saab, Arianna Sbriglione, Giuseppe A. Palumbo, Andrea Graziani, Amer M. Alanazi, Valentina Di Pietro, Barbara Tavazzi, Angela Maria Amorini, Giacomo Lazzarino
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 490 (2024)
To date, little is known concerning the circulating levels of biochemically relevant metabolites (antioxidants, oxidative/nitrosative stress biomarkers, purines, and pyrimidines) in patients with primary myelofibrosis (PMF), a rare form of myeloproli
Externí odkaz:
https://doaj.org/article/c4fff10865004c64a8c0c75fd6bf624e
Autor:
Nunzio Vicario, Federica M. Spitale, Daniele Tibullo, Cesarina Giallongo, Angela M. Amorini, Grazia Scandura, Graziana Spoto, Miriam W. Saab, Simona D’Aprile, Cristiana Alberghina, Renata Mangione, Joshua D. Bernstock, Cirino Botta, Massimo Gulisano, Emanuele Buratti, Giampiero Leanza, Robert Zorec, Michele Vecchio, Michelino Di Rosa, Giovanni Li Volti, Giuseppe Lazzarino, Rosalba Parenti, Rosario Gulino
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-13 (2021)
Abstract Motoneuronal loss is the main feature of amyotrophic lateral sclerosis, although pathogenesis is extremely complex involving both neural and muscle cells. In order to translationally engage the sonic hedgehog pathway, which is a promising ta
Externí odkaz:
https://doaj.org/article/2f7b2c74627f4e859b99f24865313a4e
Autor:
Ann Logan, Antonio Belli, Valentina Di Pietro, Barbara Tavazzi, Giacomo Lazzarino, Renata Mangione, Giuseppe Lazzarino, Inés Morano, Omar Qureshi, Lars Bruce, Nicholas M. Barnes, Zsuzsanna Nagy
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Acute and chronic neurodegenerative diseases represent an immense socioeconomic burden that drives the need for new disease modifying drugs. Common pathogenic mechanisms in these diseases are evident, suggesting that a platform neuroprote
Externí odkaz:
https://doaj.org/article/5f494b80def644158b890d705076d295
Autor:
Giacomo Lazzarino, Renata Mangione, Miriam Wissam Saab, Barbara Tavazzi, Alessandra Pittalà, Stefano Signoretti, Valentina Di Pietro, Giuseppe Lazzarino, Angela Maria Amorini
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 985 (2023)
To date, there is no information on the effect of TBI on the changes in brain CoQ levels and possible variations in its redox state. In this study, we induced graded TBIs (mild TBI, mTBI and severe TBI, sTBI) in male rats, using the weight-drop close
Externí odkaz:
https://doaj.org/article/17bbf2aa8d1a457fa6ac1d273d7b181b
Autor:
Giacomo Lazzarino, Angela M. Amorini, Renata Mangione, Miriam Wissam Saab, Enrico Di Stasio, Michelino Di Rosa, Barbara Tavazzi, Giuseppe Lazzarino, Graziano Onder, Angelo Carfì
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1208 (2022)
Down Syndrome (DS) is a neurodevelopmental disorder that is characterized by an accelerated aging process, frequently associated with the development of Alzheimer’s disease (AD). Previous studies evidenced that DS patients have various metabolic an
Externí odkaz:
https://doaj.org/article/ce877677eba94bb8ac555832920ec049
Autor:
Amorini, Renata Mangione, Romina Pallisco, Gabriele Bilotta, Francesca Marroni, Valentina Di Pietro, Elena Capoccia, Giuseppe Lazzarino, Barbara Tavazzi, Giacomo Lazzarino, Pasquale Bilotta, Angela Maria
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10707
In a previous study, we showed that various low-molecular-weight compounds in follicular fluid (FF) samples of control fertile females (CFF) have different concentrations compared to those found in FF of infertile females (IF), before and after their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0c560169b8ac76943b6596ecaff5aa1e
Autor:
Angela Maria Amorini, Ilaria Listorti, Gabriele Bilotta, Romina Pallisco, Miriam Wissam Saab, Renata Mangione, Benedetta Manca, Giacomo Lazzarino, Barbara Tavazzi, Giuseppe Lazzarino, Pasquale Bilotta
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 220 (2021)
Under physiological conditions, reactive oxygen species (ROS) play pivotal roles in various processes of human spermatozoa. Indeed, semen requires the intervention of ROS to accomplish different stages of its maturation. However, ROS overproduction i
Externí odkaz:
https://doaj.org/article/86e3c118661e4eec8a50b2aa2e752e75