Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Renata Kozevnikovova"'
Autor:
Petr Holý, Veronika Brynychová, Karolína Šeborová, Vojtěch Haničinec, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Pavel Souček
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2074-2089 (2023)
Oxysterols, oxidized derivatives of cholesterol, act in breast cancer (BC) as selective estrogen receptor modulators and affect cholesterol homeostasis, drug transport, nuclear and cell receptors, and other signaling proteins. Using data from three h
Externí odkaz:
https://doaj.org/article/dc346fd6f49f495581f9e427e684f5cc
Autor:
Viktor Hlaváč, Radka Václavíková, Veronika Brynychová, Pavel Ostašov, Renata Koževnikovová, Katerina Kopečková, David Vrána, Jiří Gatěk, Pavel Souček
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 2826 (2021)
Breast cancer is the most frequent cancer in the female population worldwide. The role of germline genetic variability in cytochromes P450 (CYP) in breast cancer prognosis and individualized therapy awaits detailed elucidation. In the present study,
Externí odkaz:
https://doaj.org/article/d62fec867dff44eaa6a7d8885d943d91
Autor:
Viktor Hlaváč, Radka Václavíková, Veronika Brynychová, Renata Koževnikovová, Katerina Kopečková, David Vrána, Jiří Gatěk, Pavel Souček
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9556 (2020)
Breast cancer is the most common cancer in women in the world. The role of germline genetic variability in ATP-binding cassette (ABC) transporters in cancer chemoresistance and prognosis still needs to be elucidated. We used next-generation sequencin
Externí odkaz:
https://doaj.org/article/beeb71dcf1cb42a8a5dc3976ed53e230
Autor:
Michal Vocka, Martina Zimovjanova, Zuzana Bielcikova, Petra Tesarova, Lubos Petruzelka, Martin Mateju, Ludmila Krizova, Jaroslav Kotlas, Jana Soukupova, Marketa Janatova, Petra Zemankova, Petra Kleiblova, Jan Novotny, Bohuslav Konopasek, Martina Chodacka, Milan Brychta, Marek Sochor, Denisa Smejkalova-Musilova, Vlastimila Cmejlova, Renata Kozevnikovova, Lenka Miskarova, Sona Argalacsova, Lenka Stolarova, Klara Lhotova, Marianna Borecka, Zdenek Kleibl
Publikováno v:
Cancers, Vol 11, Iss 6, p 738 (2019)
Breast cancer (BC) prognosis in BRCA1 and BRCA2 mutation carriers has been reported contradictorily, and the significance of variables influencing prognosis in sporadic BC is not established in BC patients with hereditary BRCA1/BRCA2 mutations. In th
Externí odkaz:
https://doaj.org/article/397dffc6e38347ff8d5660ff71b42cc0
Autor:
Viktor Hlavac, Maria Kovacova, Katerina Elsnerova, Veronika Brynychova, Renata Kozevnikovova, Karel Raus, Katerina Kopeckova, Sona Mestakova, David Vrana, Jiri Gatek, Pavel Ostasov, Radka Vaclavikova, Pavel Soucek
Publikováno v:
Cancers, Vol 10, Iss 12, p 511 (2018)
The aim of our study was to set up a panel for targeted sequencing of chemoresistance genes and the main transcription factors driving their expression and to evaluate their predictive and prognostic value in breast cancer patients. Coding and regula
Externí odkaz:
https://doaj.org/article/427183575b1b4106b3a9a4b8ccc9c89a
Autor:
Veronika Vymetalkova, Pavel Soucek, Tereza Kunicka, Katerina Jiraskova, Veronika Brynychova, Barbara Pardini, Vendula Novosadova, Zdena Polivkova, Katerina Kubackova, Renata Kozevnikovova, Miloslav Ambrus, Ludmila Vodickova, Alessio Naccarati, Pavel Vodicka
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134463 (2015)
Variations in the TP53 gene have been suggested to play a role in many cancers, including breast. We previously observed an association between TP53 haplotypes based on four polymorphisms (rs17878362, rs1042522, rs12947788, and rs17884306) and the ri
Externí odkaz:
https://doaj.org/article/daa9818343444ee98abf92c5511e42d0
Autor:
Viktor Hlavac, Pavel Soucek, Radka Vaclavikova, David Vrána, Veronika Brynychova, Pavel Dvorak, J Gatek, Karel Rauš, Katerina Elsnerova, Katerina Kopeckova, Renata Kozevnikovova, Sona Mestakova
Publikováno v:
Molecular Diagnosis & Therapy. 25:99-110
Membrane solute carrier transporters play an important role in the transport of a wide spectrum of substrates including anticancer drugs and cancer-related physiological substrates. This study aimed to assess the prognostic relevance of gene expressi
Autor:
Katerina Lickova, Pavel Soucek, Andrea Cumova, Alena Opattova, Ludmila Vodickova, Pavel Vodicka, Barbara Pardini, Katerina Kopeckova, Renata Kozevnikovova, Veronika Vymetalkova, Miloslav Ambrus, Veronika Bouskova, Alessio Naccarati
Publikováno v:
Mutagenesis. 36(4)
Breast cancer (BC) is the most frequent malignancy in women accounting for approximately 2 million new cases worldwide annually. Several genetic, epigenetic and environmental factors are known to be involved in BC development and progression, includi
Autor:
Renata Kozevnikovova, Miloslav Ambrus, Michal Kroupa, Kari Hemminki, Ludmila Vodickova, Sivaramakrishna Rachakonda, Michaela Schneiderova, Rajesh Kumar, Ludovit Musak, Zdenka Polivkova, Pavel Vodicka, Sona Vodenkova
Publikováno v:
Oncology reports. 44(5)
Accumulation of non‑specific structural chromosomal aberrations (CAs) and telomere shortening contribute to genome instability, which constitutes as one of the hallmarks of cancer. CAs arise due to direct DNA damage or telomere shortening. CAs in p
Autor:
Pavel Soucek, Shouzou Wei, F. P. Guengerich, Renata Kozevnikovova, Yune-Fang Ueng, David Vrána
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 56:e78-e81
Introduction Oxygenated metabolites of cholesterol (“oxysterols”) can influence carcinogenesis and contribute to resistance to endocrine therapy, an effect mostly described in vitro. Objectives We sought to establish a method for screening plasma