Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Renata Ialchina"'
Autor:
Dominika Czaplinska, Renata Ialchina, Henriette Berg Andersen, Jiayi Yao, Arnaud Stigliani, Johs Dannesboe, Mette Flinck, Xiaoming Chen, Jakub Mitrega, Sebastian Peter Gnosa, Oksana Dmytriyeva, Frauke Alves, Joanna Napp, Albin Sandelin, Stine Falsig Pedersen
Publikováno v:
International Journal of Cancer
Czaplinska, D, Ialchina, R, Andersen, H B, Yao, J, Stigliani, A, Dannesboe, J, Flinck, M, Chen, X, Mitrega, J, Gnosa, S P, Dmytriyeva, O, Alves, F, Napp, J, Sandelin, A & Pedersen, S F 2023, ' Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness ', International Journal of Cancer, vol. 152, no. 6, pp. 1210-1225 . https://doi.org/10.1002/ijc.34367
Czaplinska, D, Ialchina, R, Andersen, H B, Yao, J, Stigliani, A, Dannesboe, J, Flinck, M, Chen, X, Mitrega, J, Gnosa, S P, Dmytriyeva, O, Alves, F, Napp, J, Sandelin, A & Pedersen, S F 2023, ' Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness ', International Journal of Cancer, vol. 152, no. 6, pp. 1210-1225 . https://doi.org/10.1002/ijc.34367
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy with minimal treatment options and a global rise in prevalence. PDAC is characterized by frequent driver mutations including KRAS and TP53 (p53), and a dense, acidic tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c1f1b4aea4a4a89a3745f8fff18c02
https://hdl.handle.net/21.11116/0000-000C-45F6-121.11116/0000-000C-45F8-F
https://hdl.handle.net/21.11116/0000-000C-45F6-121.11116/0000-000C-45F8-F
Autor:
Arnaud Stigliani, Renata Ialchina, Jiayi Yao, Dominika Czaplinska, Yifan Dai, Henriette Berg Andersen, Robin Andersson, Stine Falsig Pedersen, Albin Sandelin
The harsh environments in poorly perfused tumor regions have been proposed to select for traits that may drive cancer aggressiveness. Here, we tested the hypothesis that tumor acidosis interacts with driver mutations to exacerbate cancer hallmarks, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce822599f58ab3c578553df48b75efb
https://doi.org/10.1101/2023.01.02.522472
https://doi.org/10.1101/2023.01.02.522472
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers globally with a mortality rate exceeding 95% and very limited therapeutic options. A hallmark of PDAC is its acidic tumor microenvironment, further characterized by excessive fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8543de1926e299b071db4a4e6a888e3
https://zenodo.org/record/8118032
https://zenodo.org/record/8118032
Autor:
Olga V. Sergeeva, Timofei S. Zatsepin, Anna Kosyreva, Varvara Varlamova, Tatiana O. Abakumova, Evgeniya Shcherbinina, Tatiana Prikazchikova, Ilia Kurochkin, Renata Ialchina
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6958, p 6958 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6958, p 6958 (2021)
DDX3 RNA helicase is intensively studied as a therapeutic target due to participation in the replication of some viruses and involvement in cancer progression. Here we used transcriptome analysis to estimate the primary response of hepatocytes to dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7864abd5949ce05772027f083caaa78c
https://doi.org/10.3390/ijms22136958
https://doi.org/10.3390/ijms22136958
Autor:
Dominika Czaplinska, Albin Sandelin, Julie Schnipper, Jiayi Yao, Bin Liu, Renata Ialchina, Stine F. Pedersen
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2183, p 2183 (2020)
Volume 12
Issue 8
Yao, J, Czaplinska, D, Ialchina, R, Schnipper, J, Liu, B, Sandelin, A & Pedersen, S F 2020, ' Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival ', Cancers, vol. 12, no. 8, 2183 . https://doi.org/10.3390/cancers12082183
Cancers, Vol 12, Iss 2183, p 2183 (2020)
Volume 12
Issue 8
Yao, J, Czaplinska, D, Ialchina, R, Schnipper, J, Liu, B, Sandelin, A & Pedersen, S F 2020, ' Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival ', Cancers, vol. 12, no. 8, 2183 . https://doi.org/10.3390/cancers12082183
The acidic pH of the tumor microenvironment plays a critical role in driving cancer development toward a more aggressive phenotype, but the underlying mechanisms are unclear. To this end, phenotypic and genotypic changes induced by adaptation of canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36454e2d970b93ad5a7179d2d3b8f667
https://doi.org/10.3390/cancers12082183
https://doi.org/10.3390/cancers12082183