Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Renata Haugvicová"'
Publikováno v:
Physiological Research. :S361-S366
Mechanism of ictogenesis of D- and L-stereroisomers of homocysteic acid was studied in 12-day-old rats by means of antagonists of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. There was no
Publikováno v:
Brain Research. 1273:144-154
The present study has examined the anticonvulsant and neuroprotective effect of 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate (2R,4R-APDC), a selective agonist for group II metabotropic glutamate receptors (mGluRs) when given 10–15 min after the onset
Publikováno v:
Neuropharmacology. 54:665-675
The present study has examined the anticonvulsant and neuroprotective effect of ( S )-3,4-dicarboxyphenylglycine (( S )-3,4-DCPG), a highly selective agonist for subtype 8 of group III metabotropic glutamate receptors (mGluRs), against seizures induc
Autor:
Jiřina Slaninová, Resha Matyšková, Lenka Maletínská, Jana Maixnerová, Eva Sloncova, Blanka Železná, Renata Haugvicová, Tomáš Elbert
Publikováno v:
European Journal of Pharmacology. 559:109-114
CART (cocaine- and amphetamine-regulated transcript) peptides have been studied for ten years. We report specific binding of 125I-CART(61-102) to the rat adrenal pheochromocytoma PC12 cell line, both intact cells and cell membranes. Saturation bindin
Autor:
Pavel Mareš, Jaroslava Folbergrová, Rastislav Druga, Renata Haugvicová, Jakub Otáhal, Hana Kubová
Publikováno v:
Experimental Neurology. 192:420-436
The present study has examined the anticonvulsant and neuroprotective effect of group II metabotropic glutamate receptor (mGluR) agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (2R,4R-APDC) in the model of seizures induced in immature 12-day-old
Publikováno v:
Experimental Neurology. 180:46-54
The potential anticonvulsant effect of group III metabotropic glutamate receptor (mGluR) agonist (R,S)-4-phosphonophenylglycine ((R,S)-PPG) against seizures induced in immature 12-day-old rats by bilateral intracerebroventricular (icv) infusion of DL
Publikováno v:
Epilepsia. 43:61-67
Summary: Purpose: To determine the role of excitatory amino acids (EAAs) in genesis of two types of epileptic afterdischarges. Methods: Cortical stimulation and recording electrodes were implanted in 12-, 18-, and 25-day-old rats. Epileptic afterdisc
Publikováno v:
Epilepsia. 43:54-60
Summary: Purpose: Status epilepticus (SE) was previously found to induce damage in the mediodorsal nucleus of the thalamus (MD) in both adult and immature rats. This study was designed to describe age-related changes of SE-induced neuronal degenerati
Publikováno v:
Developmental Brain Research. 133:69-75
Maturation of the brain adenylyl cyclase (AC) signalling system was investigated in the developing rat cortex, thalamus and hippocampus. Expression of AC type II, IV and VI measured by Western blot dramatically increased in all tested brain regions d
Publikováno v:
Epilepsy & Behavior. 2:473-480
It is not known if nonconvulsive seizures lead to functional or morphological changes in immature rats. Therefore we studied consequences of such seizures induced by kainic acid (KA) on Postnatal Day (PD) 12 (2 mg/kg ip). The animals were examined el