Interobserver Variation in the Assessment of Immunohistochemistry Expression Levels in HER2-Negative Breast Cancer: Can We Improve the Identification of Low Levels of HER2 Expression by Adjusting the Criteria? An International Interobserver Study

Autor: Ximena Baez-Navarro, Mieke R. van Bockstal, Diënna Nawawi, Glenn Broeckx, Cecile Colpaert, Shusma C. Doebar, Marieke C.H. Hogenes, Esther Koop, Kathleen Lambein, Dieter J.E. Peeters, Renata H.J.A. Sinke, Johannes Bastiaan van Brakel, José van der Starre-Gaal, Bert van der Vegt, Koen van de Vijver, Celien P.H. Vreuls, Willem Vreuls, Pieter J. Westenend, Carolien H.M. van Deurzen

Publikováno v: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 36(1):100009. Nature Publishing Group
Modern pathology

The classification of human epidermal growth factor receptor 2 (HER2) expression is optimized to detect HER2-amplified breast cancer (BC). However, novel HER2-targeting agents are also effective for BCs with low levels of HER2. This raises the questi

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https://pure.eur.nl/en/publications/018e2521-96dd-4830-a731-e34e7c786351