Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Renata Gustafsson"'
Autor:
P. Olof Olsson, Renata Gustafsson, Alexei V. Salnikov, Maria Göthe, Kathrin S. Zeller, Tomas Friman, Bo Baldetorp, Louise A. Koopman, Paul H. Weinreb, Shelia M. Violette, Sebastian Kalamajski, Nils-Erik Heldin, Kristofer Rubin
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Chemotherapeutic efficacy can be improved by targeting the structure and function of the extracellular matrix (ECM) in the carcinomal stroma. This can be accomplished by e.g. inhibiting TGF-β1 and -β3 or treating with Imatinib,
Externí odkaz:
https://doaj.org/article/fe3d1f86aca84e059d01cd634fae0c7c
Autor:
Tiina Kelkka, Angela Pizzolla, Juha Petteri Laurila, Tomas Friman, Renata Gustafsson, Eva Källberg, Olof Olsson, Tomas Leanderson, Kristofer Rubin, Marko Salmi, Sirpa Jalkanen, Rikard Holmdahl
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84148 (2013)
The NADPH oxidase 2 (NOX2) complex is a professional producer of reactive oxygen species (ROS) and is mainly expressed in phagocytes. While the activity of the NOX2 complex is essential for immunity against pathogens and protection against autoimmuni
Externí odkaz:
https://doaj.org/article/629b2ea2440d403f8ae446a5756aa0bf
Autor:
Tomas Friman, Renata Gustafsson, Linda B Stuhr, Jean Chidiac, Nils-Erik Heldin, Rolf K Reed, Ake Oldberg, Kristofer Rubin
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34082 (2012)
Stroma properties affect carcinoma physiology and direct malignant cell development. Here we present data showing that α(V)β(3) expressed by stromal cells is involved in the control of interstitial fluid pressure (IFP), extracellular volume (ECV) a
Externí odkaz:
https://doaj.org/article/580b4f5088014710824333edcefec483
Autor:
Sebastian Kalamajski, Kristofer Rubin, Åke Oldberg, Emil Tykesson, Marco Maccarana, Tomas Friman, René in 't Zandt, Renata Gustafsson, P. Olof Olsson
Collagen synthesis in STI571-treated KAT-4 carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aec9aff7e473806a84936e061d4e77e
https://doi.org/10.1158/1535-7163.22504249.v1
https://doi.org/10.1158/1535-7163.22504249.v1
Autor:
Sebastian Kalamajski, Kristofer Rubin, Åke Oldberg, Emil Tykesson, Marco Maccarana, Tomas Friman, René in 't Zandt, Renata Gustafsson, P. Olof Olsson
Summary of real-time PCR results. Table showing expression levels of selected genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a8ba8c3e943d9f76c0d0b08d770c04
https://doi.org/10.1158/1535-7163.22504246
https://doi.org/10.1158/1535-7163.22504246
Autor:
Xanthi Stachtea, Renata Gustafsson, Marco Maccarana, Åke Oldberg, Erik A. Eklund, Emma Grottling, Anders Malmström
Publikováno v:
Birth Defects Research. Part A: Clinical and Molecular Teratology; 100(9), pp 712-720 (2014)
Birth Defects Research. Part A, Clinical and Molecular Teratology
Birth Defects Research. Part A, Clinical and Molecular Teratology
Background Dermatan sulfate (DS) is a highly sulfated polysaccharide with a variety of biological functions in extracellular matrix organization and processes such as tumorigenesis and wound healing. A distinct feature of DS is the presence of iduron
Publikováno v:
Biochemical Journal
The functional significance of fibrin deposits typically seen in inflammatory lesions, carcinomas and in healing wounds is not fully understood. In the present study, we demonstrate that fibrinogen/fibrin specifically bound to native Col I (collagen
Autor:
Emil Tykesson, Anders Malmström, Martin A. Thelin, Barbara Bartolini, Edgar M. Pera, Jakob B Axelsson, Åke Oldberg, Renata Gustafsson, Marco Maccarana
Publikováno v:
The Febs Journal
The presence of iduronic acid in chondroitin/dermatan sulfate changes the properties of the polysaccharides because it generates a more flexible chain with increased binding potentials. Iduronic acid in chondroitin/dermatan sulfate influences multipl
Autor:
Sebastian Kalamajski, Annelie Shami, Rob Krams, Gunnel Roos, Åke Oldberg, Jan Nilsson, Uwe Rauch, Renata Gustafsson, Anna Hultgårdh-Nilsson, Dolf Segers
Publikováno v:
Arteriosclerosis, Thrombosis and Vascular Biology; (2012)
Objective— The aim of this study was to analyze how an altered collagen structure affects development of atherosclerotic plaques. Methods and Results— Fibromodulin-null mice develop an abnormal collagen fibril structure. In apolipoprotein E (ApoE
Autor:
Roger Hesselstrand, Renata Gustafsson, Kristina Rydell-Törmänen, Gunilla Westergren-Thorsson, Kristofer Andréasson, Tore Saxne
Publikováno v:
Experimental dermatology. 25(7)
Excessive production of collagen is the hallmark of fatal diseases of fibrosis such as systemic sclerosis. Overexpression of the proteoglycan fibromodulin (FMOD) has been associated with improved wound healing and scarless repair. In this study we ha