Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Renata Grozovsky"'
Autor:
William J. Reagan, Marjory B. Brooks, Renata Grozovsky, Debra Pittman, Allison Vitsky, Karrie Brenneman
Publikováno v:
Toxicologic Pathology. 50:890-894
The session on the hemostatic system focused on new developments in coagulation and platelet biology as well as how therapeutic agents may affect hemostasis. The classic cascade model of coagulation was compared with the more recent models of cell-ba
Autor:
Katelyn E. Rosenbalm, Melissa M. Lee-Sundlov, David J. Ashline, Renata Grozovsky, Kazuhiro Aoki, Andrew J. S. Hanneman, Karin M. Hoffmeister
Publikováno v:
Blood Advances.
Changes in surface glycan determinants, specifically sialic acid loss, determine platelet life span. The gradual loss of stored platelet quality is a complex process that fundamentally involves carbohydrate structures. Here, we applied lipophilic ext
Autor:
Anahita Nourmahnad, Julian A. Purrinos, Renata Grozovsky, Angela M. Richardson, Corinna G. Levine
Publikováno v:
32nd Annual Meeting North American Skull Base Society.
Autor:
Hidehiro Itonaga, Adnan Mookhtiar, Sarah Greenblatt, Fan Liu, Concepcion Martinez, Renata Grozovsky, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas, Stephan Schurer, Stephen Nimer
Coactivator-associated arginine methyltransferase 1 (CARM1) is overexpressed in cancer, and it has emerged as an important target in acute myeloid leukemia and other hematologic malignancies. Janus kinase 2 (JAK2), that is activated by mutation in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09bd3b01bdc63f12dd0231309329ca96
https://doi.org/10.21203/rs.3.rs-1807575/v1
https://doi.org/10.21203/rs.3.rs-1807575/v1
Autor:
Hidehiro Itonaga, Adnan K Mookhtiar, Sarah Greenblatt, Fan Liu, Concepcion Martinez, Renata Grozovsky, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas Martin, Stephen Schürer, Stephen D Nimer
Publikováno v:
Blood. 140:3021-3022
Autor:
Robert Burns, Jenny M. Despotovic, Simon H. Glabere, Silvia Giannini, Melissa M. Lee-Sundlov, Walter H. A. Kahr, Yongwei Zheng, Renata Grozovsky, Reza Abdi, Taylor Olmsted Kim, Karin M. Hoffmeister, Leonardo Rivadeneyra, Demin Wang
Publikováno v:
Blood
Immune thrombocytopenia (ITP) is a platelet disorder. Pediatric and adult ITP have been associated with sialic acid alterations, but the pathophysiology of ITP remains elusive, and ITP is often a diagnosis of exclusion. Our analysis of pediatric ITP
Autor:
Yongwei Zheng, Renata Grozovsky, Silvia Giannini, Robert Burns, Simon H. Glabere, Walter H. A. Kahr, Reza Abdi, Melissa M. Lee-Sundlov, Karin M. Hoffmeister, Leonardo Rivadeneyra, Demin Wang
Publikováno v:
SSRN Electronic Journal.
The Thomsen-Friedenreich antigen (TF-antigen) occurs during exposure of the underlying Core-1 disaccharide (Gal-beta(1,3)GalNAc) through the loss of its capping sialic acid (Sia). Exposure of the cryptic TF-antigen occurs during inflammation, during
Autor:
Joseph T.Y. Lau, David J. Ashline, Karin M. Hoffmeister, Andrew J. Hanneman, Renata Grozovsky, Vernon N. Reinhold, Melissa M. Lee-Sundlov
Publikováno v:
Glycobiology. 27:188-198
Glycosyltransferases, usually residing within the intracellular secretory apparatus, also circulate in the blood. Many of these blood-borne glycosyltransferases are associated with pathological states, including malignancies and inflammatory conditio
Publikováno v:
Blood. 126:1877-1884
The human body produces and removes 1011 platelets daily to maintain a normal steady state platelet count. Platelet production must be regulated to avoid spontaneous bleeding or arterial occlusion and organ damage. Multifaceted and complex mechanisms
Autor:
Silvia Giannini, Cameron Fraser, Kristopher A. Sarosiek, Karin M. Hoffmeister, Renata Grozovsky
Publikováno v:
Blood. 134:1055-1055
Our understanding of cell biological processes involved in aging has advance greatly over the past decades. Platelets are small cells that circulate for 4-5 days in mice and 7-10 days in humans. And even though, platelets are anucleated cells, a grow