Výsledky vyhledávání - "Renata Gattoni"

Roles of hnRNP A1, SR Proteins, and p68 Helicase in c-H-ras Alternative Splicing Regulation

Autor: Sonia Guil, Montse Bach-Elias, Renata Gattoni, Joaquín Abián, James Stévenin, Montserrat Carrascal

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Human ras genes play central roles in coupling extracellular signals with complex intracellular networks controlling proliferation, differentiation, and apoptosis, among others processes. c-H-ras pre-mRNA can be alternatively processed into two mRNAs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24472652d8671fd187953517dbc1b099
https://doi.org/10.1128/mcb.23.8.2927-2941.2003

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SR Splicing Factors Serve as Adapter Proteins for TAP-Dependent mRNA Export

Autor: James Stévenin, Renata Gattoni, Yingqun Huang, Joan A. Steitz

Publikováno v: Molecular Cell. 11:837-843

The only mammalian RNA binding adapter proteins known to partner with TAP/NXF1, the primary receptor for general mRNA export, are members of the REF family. We demonstrate that at least three shuttling SR (serine/arginine-rich) proteins interact with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9790bd67e65d0fd7a4132ee5102270eb
https://doi.org/10.1016/s1097-2765(03)00089-3

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[Untitled]

Autor: Andrea Barta, Renata Gattoni, James Stévenin, Sergiy Lopato, Gustáv Fabini

Publikováno v: Plant Molecular Biology. 39:761-773

An important group of splicing factors involved in constitutive and alternative splicing contain an arginine/serine (RS)-rich domain. We have previously demonstrated the existence of such factors in plants and report now on a new family of splicing f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30433ff5fc0999174eee9124716d74a9
https://doi.org/10.1023/a:1006129615846

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Characterization of SRp46, a Novel Human SR Splicing Factor Encoded by a PR264/SC35 Retropseudogene

Autor: James Stévenin, Michel Popielarz, Cécile Guyon, Bernard Dutrillaux, Bernard Perbal, Alain Sureau, Stephanie Dumon, Françoise Apiou, H. Voss, Johann Soret, Renata Gattoni, Wilhelm Ansorge, Erwann Le Rouzic

Publikováno v: Molecular and Cellular Biology. 18:4924-4934

The highly conserved SR family contains a growing number of phosphoproteins acting as both essential and alternative splicing factors. In this study, we have cloned human genomic and cDNA sequences encoding a novel SR protein designated SRp46. Nucleo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fda58ad20162c1f9c07e2a73c8dc6ed
https://doi.org/10.1128/mcb.18.8.4924

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Cloning of Human 2H9 Heterogeneous Nuclear Ribonucleoproteins

Autor: Philippe Mähl, Jean-Paul Fuchs, Dominique Mahé, Nadine Fischer, Renata Gattoni, Marie-Geneviève Mattei, James Stévenin

Publikováno v: Journal of Biological Chemistry. 272:1827-1836

Using antibody 2H9 from our heterogeneous nuclear ribonucleoproteins (anti-hnRNP) monoclonal antibody library, we previously showed in HeLa cells that a 35-37-kDa protein doublet switches from the hnRNP complexes to the nuclear matrix following a 10-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a49382789cc200dbaff7b89437be1d5c
https://doi.org/10.1074/jbc.272.3.1827

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The human hnRNP-M proteins: structure and relation with early heat shock-induced splicing arrest and chromosome mapping

Autor: Nadine Fischer, Jean-Paul Fuchs, James Stévenin, Marie-Geneviève Mattei, Philippe Mähl, Renata Gattoni, Dominique Mahé

Publikováno v: Nucleic Acids Research. 24:2535-2542

With anti-hnRNP monoclonal antibody 6D12 we previously showed in HeLa cells that as early as 10 min after the onset of a heat shock at 45 degrees C, a 72.5-74 kDa antigen doublet leaves the hnRNPs and strongly associates with the nuclear matrix, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1c256fbe0c3332150aa58c1becb67c
https://doi.org/10.1093/nar/24.13.2535

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The Gene Encoding Human Splicing Factor 9G8

Autor: Marie-Genevive Mattei, Renata Gattoni, James Stvenin, Yvon Cavaloc, Michel Popielarz

Publikováno v: Journal of Biological Chemistry. 270:17830-17835

The 9G8 factor is a 30-kDa member of the SR splicing factor family. We report here the isolation and characterization of the human 9G8 gene. This gene spans 7745 nucleotides and consists of 8 exons and 7 introns within the coding sequence, thus contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbaa793957fee7f51a318f62d9c9d9f0
https://doi.org/10.1074/jbc.270.30.17830

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Contrastedcis-acting effects of downstream 5′ splice sites on the splicing of a retained intron: the adenoviral E1A pre-mRNA model

Autor: James Stevenin, Michel Popielarz, Renata Gattoni

Publikováno v: Nucleic Acids Research. 21:5144-5151

The adenoviral E1A pre-mRNA contains an upstream intron (the 216 nucleotide intron) which is spliced only weakly both in vivo and in vitro. We have chosen the E1A transcript as a model to analyse, in vitro, the role of downstream cis-elements involve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3924601915b998200ffaf5ad29e4fce3
https://doi.org/10.1093/nar/21.22.5144

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Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients

Autor: Chantal Sellier, Anne Schneider, Frédérique Rau, Yilei Liu, Stéphane Richard, Nicolas Charlet-Berguerand, Renate K. Hukema, David J. Elliott, Rob Willemsen, Renata Gattoni, Flora Tassone, Paul J. Hagerman

Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2010, 29 (7), pp.1248-1261. ⟨10.1038/emboj.2010.21⟩
EMBO Journal, 2010, 29 (7), pp.1248-1261. ⟨10.1038/emboj.2010.21⟩
EMBO Journal, 29(7), 1248-1261. Wiley-Blackwell

Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder caused by expansion of 55-200 CGG repeats in the 5'-UTR of the FMR1 gene. FXTAS is characterized by action tremor, gait ataxia and impaired executive cognitive functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c416aeca41f20403f50a8e33ad3ae57f
https://hal.archives-ouvertes.fr/hal-03339578

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Modulation of alternative splicing of adenoviral E1A transcripts: factors involved in the early-to-late transition

Autor: Renata Gattoni, M Himmelspach, James Stévenin, Karim Chebli

Publikováno v: Genes & Development. 5:1847-1858

The E1A pre-mRNA of adenovirus is spliced into three mRNA species (13S, 12S, and 9S mRNAs) by the use of three alternative 5'-splice sites. The 13S and 9S mRNAs predominate during the early and late periods of infection, respectively. With HeLa nucle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f72fe7210c416f4cc66a801b9c541e5
https://doi.org/10.1101/gad.5.10.1847

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