Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Renata E. P. Leite"'
Autor:
Alinny R. Isaac, Mariana G. Chauvet, Ricardo Lima-Filho, Beatriz de A. Wagner, Bruno G. Caroli, Renata E. P. Leite, Claudia K. Suemoto, Paula Villela Nunes, Fernanda G. De Felice, Sergio T. Ferreira, Mychael V. Lourenco
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Major depressive disorder (MDD) is a significant cause of disability in adults worldwide. However, the underlying causes and mechanisms of MDD are not fully understood, and many patients are refractory to available therapeutic options. Impai
Externí odkaz:
https://doaj.org/article/00a284daaf5a498985eae3582d1517e8
Autor:
Regina Silva Paradela, Alberto Fernando Oliveira Justo, Vítor Ribeiro Paes, Renata E. P. Leite, Carlos A. Pasqualucci, Lea T. Grinberg, Michel Satya Naslavsky, Mayana Zatz, Ricardo Nitrini, Wilson Jacob-Filho, Claudia Kimie Suemoto
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Background Apolipoprotein E ε4 allele (APOE-ε4) is the main genetic risk factor for late-onset Alzheimer’s disease (AD) and may impact cognitive function also via other neuropathological lesions. However, there is limited evidence availa
Externí odkaz:
https://doaj.org/article/1cb2435c440542a187c72e5b2f821d40
Autor:
Felipe C. Ribeiro, Danielle Cozachenco, Luana Heimfarth, Juliana T. S. Fortuna, Guilherme B. de Freitas, Jorge M. de Sousa, Soniza V. Alves-Leon, Renata E. P. Leite, Claudia K. Suemoto, Lea T. Grinberg, Fernanda G. De Felice, Mychael V. Lourenco, Sergio T. Ferreira
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The proteasome plays key roles in synaptic plasticity and memory by regulating protein turnover, quality control, and elimination of oxidized/misfolded proteins. Here, we investigate proteasome function and localization at synapses in Alzhei
Externí odkaz:
https://doaj.org/article/bdf4804051b140dd9c552fb96120595a
Autor:
Isadora Matias, Luan Pereira Diniz, Ana Paula Bergamo Araujo, Isabella Vivarini Damico, Pâmella de Moura, Felipe Cabral-Miranda, Fabiola Diniz, Belisa Parmeggiani, Valeria de Mello Coelho, Renata E. P. Leite, Claudia K. Suemoto, Gustavo Costa Ferreira, Regina Célia Cussa Kubrusly, Flávia Carvalho Alcantara Gomes
Publikováno v:
ASN Neuro, Vol 15 (2023)
Aging is marked by complex and progressive physiological changes, including in the glutamatergic system, that lead to a decline of brain function. Increased content of senescent cells in the brain, such as glial cells, has been reported to impact cog
Externí odkaz:
https://doaj.org/article/a97d7ca348904013a93951594460c987
Autor:
Aline Nishizawa, Anderson Cuelho, Daniela S. de Farias-Itao, Fernanda M. Campos, Renata E. P. Leite, Renata E. L. Ferretti-Rebustini, Lea T. Grinberg, Ricardo Nitrini, Wilson Jacob-Filho, Carlos A. Pasqualucci, Claudia K. Suemoto
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Background: The relationship between cognitive impairment and abdominal visceral is controversial. Moreover, all studies so far used imaging studies to evaluate visceral fat and this association has not been described yet using autopsy material, whic
Externí odkaz:
https://doaj.org/article/21415e0fe2d04d7d8841444a6bb94c43
Autor:
Sarah Plum, Britta Eggers, Stefan Helling, Markus Stepath, Carsten Theiss, Renata E. P. Leite, Mariana Molina, Lea T. Grinberg, Peter Riederer, Manfred Gerlach, Caroline May, Katrin Marcus
Publikováno v:
Cells, Vol 9, Iss 12, p 2580 (2020)
The pathological hallmark of Parkinson’s disease (PD) is the loss of neuromelanin-containing dopaminergic neurons within the substantia nigra pars compacta (SNpc). Additionally, numerous studies indicate an altered synaptic function during disease
Externí odkaz:
https://doaj.org/article/a6d14feb8d634539a742d87c98fb4de9
Autor:
Eliana C. B. Toscano, Érica L. M. Vieira, Lea T. Grinberg, Natalia P. Rocha, Joseane A. S. Brant, Regina S. Paradela, Alexandre V. Giannetti, Claudia K. Suemoto, Renata E. P. Leite, Ricardo Nitrini, Milene A. Rachid, Antonio L. Teixeira
Publikováno v:
Molecular Neurobiology. 60:2174-2185
Autor:
Lucy L, Gibson, Lea T, Grinberg, Dominic, Ffytche, Renata E P, Leite, Roberta D, Rodriguez, Renata E L, Ferretti-Rebustini, Carlos A, Pasqualucci, Ricardo, Nitrini, Wilson, Jacob-Filho, Dag, Aarsland, Claudia K, Suemoto
Publikováno v:
Alzheimer's & Dementia. 19:1372-1382
Neuropsychiatric symptoms (NPS) are common in Lewy body disease (LBD), but their etiology is poorly understood.In a population-based post mortem study neuropathological data was collected for Lewy body (LB) neuropathology, neurofibrillary tangles (NF
Autor:
Victor Bodart‐Santos, Lisandra S. Pinheiro, Almir J. da Silva‐Junior, Rudimar L. Froza, Rosemary Ahrens, Rafaella A. Gonçalves, Mayara M. Andrade, Yan Chen, Carolina de Lima Alcantara, Lea T. Grinberg, Renata E. P. Leite, Sergio T. Ferreira, Paul E. Fraser, Fernanda G. De Felice
Publikováno v:
Alzheimer's & Dementia.
Autor:
Emily Castro-Fonseca, Viviane Morais, Camila G da Silva, Juliana Wollner, Jaqueline Freitas, Arthur F Mello-Neto, Luiz E Oliveira, Vilson C de Oliveira, Renata E P Leite, Ana T Alho, Roberta D Rodriguez, Renata E L Ferretti-Rebustini, Claudia K Suemoto, Wilson Jacob-Filho, Ricardo Nitrini, Carlos A Pasqualucci, Lea T Grinberg, Fernanda Tovar-Moll, Roberto Lent
Publikováno v:
Cerebral Cortex.
The human cerebral cortex is one of the most evolved regions of the brain, responsible for most higher-order neural functions. Since nerve cells (together with synapses) are the processing units underlying cortical physiology and morphology, we studi