Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Renata E P Leite"'
Autor:
Alinny R. Isaac, Mariana G. Chauvet, Ricardo Lima-Filho, Beatriz de A. Wagner, Bruno G. Caroli, Renata E. P. Leite, Claudia K. Suemoto, Paula Villela Nunes, Fernanda G. De Felice, Sergio T. Ferreira, Mychael V. Lourenco
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Major depressive disorder (MDD) is a significant cause of disability in adults worldwide. However, the underlying causes and mechanisms of MDD are not fully understood, and many patients are refractory to available therapeutic options. Impai
Externí odkaz:
https://doaj.org/article/00a284daaf5a498985eae3582d1517e8
Autor:
Regina Silva Paradela, Alberto Fernando Oliveira Justo, Vítor Ribeiro Paes, Renata E. P. Leite, Carlos A. Pasqualucci, Lea T. Grinberg, Michel Satya Naslavsky, Mayana Zatz, Ricardo Nitrini, Wilson Jacob-Filho, Claudia Kimie Suemoto
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Background Apolipoprotein E ε4 allele (APOE-ε4) is the main genetic risk factor for late-onset Alzheimer’s disease (AD) and may impact cognitive function also via other neuropathological lesions. However, there is limited evidence availa
Externí odkaz:
https://doaj.org/article/1cb2435c440542a187c72e5b2f821d40
Autor:
Felipe C. Ribeiro, Danielle Cozachenco, Luana Heimfarth, Juliana T. S. Fortuna, Guilherme B. de Freitas, Jorge M. de Sousa, Soniza V. Alves-Leon, Renata E. P. Leite, Claudia K. Suemoto, Lea T. Grinberg, Fernanda G. De Felice, Mychael V. Lourenco, Sergio T. Ferreira
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The proteasome plays key roles in synaptic plasticity and memory by regulating protein turnover, quality control, and elimination of oxidized/misfolded proteins. Here, we investigate proteasome function and localization at synapses in Alzhei
Externí odkaz:
https://doaj.org/article/bdf4804051b140dd9c552fb96120595a
Autor:
Simone Steinbach, Mariana Molina, Lea T Grinberg, Luisa Aring, Annika Guntermann, Katrin Marcus, Helmut Heinsen, Renata E Paraizo Leite, Caroline May
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0296730 (2024)
A hallmark of Parkinson's disease is the specific degeneration of dopaminergic neurons in the substantia nigra pars compacta. Interestingly, not all of these neurons are affected to the same extent. Studies revealed that neurons located more ventrall
Externí odkaz:
https://doaj.org/article/c8e5c7a6e8da40168abe375de7542998
Autor:
Juliana C. Corrêa-Velloso, Alessandra M. Linardi, Talita Glaser, Fernando J. Velloso, Maria P. Rivas, Renata E P. Leite, Lea T. Grinberg, Henning Ulrich, Michael R. Akins, Silvana Chiavegatto, Luciana A. Haddad
Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Fragile X syndrome, the major cause of inherited intellectual disability among men, is due to deficiency of the synaptic functional regulator FMR1 protein (FMRP), encoded by the FMRP translational regulator 1 (FMR1) gene. FMR1 alt
Externí odkaz:
https://doaj.org/article/82c1751e8338441cb11b9e5fbf5ed895
Autor:
Isadora Matias, Luan Pereira Diniz, Ana Paula Bergamo Araujo, Isabella Vivarini Damico, Pâmella de Moura, Felipe Cabral-Miranda, Fabiola Diniz, Belisa Parmeggiani, Valeria de Mello Coelho, Renata E. P. Leite, Claudia K. Suemoto, Gustavo Costa Ferreira, Regina Célia Cussa Kubrusly, Flávia Carvalho Alcantara Gomes
Publikováno v:
ASN Neuro, Vol 15 (2023)
Aging is marked by complex and progressive physiological changes, including in the glutamatergic system, that lead to a decline of brain function. Increased content of senescent cells in the brain, such as glial cells, has been reported to impact cog
Externí odkaz:
https://doaj.org/article/a97d7ca348904013a93951594460c987
Autor:
Eliana C. B. Toscano, Érica L. M. Vieira, Lea T. Grinberg, Natalia P. Rocha, Joseane A. S. Brant, Regina S. Paradela, Alexandre V. Giannetti, Claudia K. Suemoto, Renata E. P. Leite, Ricardo Nitrini, Milene A. Rachid, Antonio L. Teixeira
Publikováno v:
Molecular Neurobiology. 60:2174-2185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc0b422855a323e79d10eae07b81a8b
https://doi.org/10.1007/s12035-022-03190-x
https://doi.org/10.1007/s12035-022-03190-x
Autor:
Lucy L, Gibson, Lea T, Grinberg, Dominic, Ffytche, Renata E P, Leite, Roberta D, Rodriguez, Renata E L, Ferretti-Rebustini, Carlos A, Pasqualucci, Ricardo, Nitrini, Wilson, Jacob-Filho, Dag, Aarsland, Claudia K, Suemoto
Publikováno v:
Alzheimer's & Dementia. 19:1372-1382
Neuropsychiatric symptoms (NPS) are common in Lewy body disease (LBD), but their etiology is poorly understood.In a population-based post mortem study neuropathological data was collected for Lewy body (LB) neuropathology, neurofibrillary tangles (NF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5c9ba31e9b15ca7b1f2873075bb58b
https://doi.org/10.1002/alz.12765
https://doi.org/10.1002/alz.12765
Autor:
Aline Nishizawa, Anderson Cuelho, Daniela S. de Farias-Itao, Fernanda M. Campos, Renata E. P. Leite, Renata E. L. Ferretti-Rebustini, Lea T. Grinberg, Ricardo Nitrini, Wilson Jacob-Filho, Carlos A. Pasqualucci, Claudia K. Suemoto
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Background: The relationship between cognitive impairment and abdominal visceral is controversial. Moreover, all studies so far used imaging studies to evaluate visceral fat and this association has not been described yet using autopsy material, whic
Externí odkaz:
https://doaj.org/article/21415e0fe2d04d7d8841444a6bb94c43
Autor:
Victor Bodart‐Santos, Lisandra S. Pinheiro, Almir J. da Silva‐Junior, Rudimar L. Froza, Rosemary Ahrens, Rafaella A. Gonçalves, Mayara M. Andrade, Yan Chen, Carolina de Lima Alcantara, Lea T. Grinberg, Renata E. P. Leite, Sergio T. Ferreira, Paul E. Fraser, Fernanda G. De Felice
Publikováno v:
Alzheimer's & Dementia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::612bc8150704ea1eebd4899fa5d88800
https://doi.org/10.1002/alz.13134
https://doi.org/10.1002/alz.13134