Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Renata Duchnowska"'
Autor:
Renata Duchnowska, Anna Maria Supernat, Rafał Pęksa, Marta Łukasiewicz, Tomasz Stokowy, Roy Ronen, Janusz Dutkowski, Monika Umińska, Ewa Iżycka-Świeszewska, Anna Kowalczyk, Waldemar Och, Monika Rucińska, Wojciech P. Olszewski, Tomasz Mandat, Bożena Jarosz, Michał Bieńkowski, Wojciech Biernat, Jacek Jassem
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Brain metastases (BMs) in ovarian cancer (OC) are a rare event. BMs occur most frequently in high-grade serous (HGS) OC. The molecular features of BMs in HGSOC are poorly understood. We performed a whole-exome sequencing analysis of ten matc
Externí odkaz:
https://doaj.org/article/d2d11a695913453e8ed1c77cf42a380f
Autor:
Marcin Nicoś, PhD, Luuk Harbers, MSc, Enrico Patrucco, PhD, Maximilian Kramer-Drauberg, PhD, Xiaolu Zhang, PhD, Claudia Voena, PhD, Anna Kowalczyk, MD, PhD, Aleksandra Bożyk, PhD, Rafał Pęksa, MD, PhD, Bożena Jarosz, MD, PhD, Justyna Szumiło, MD, Michele Simonetti, PhD, Monika Żuk, PhD, Bartosz Wasąg, MD, Katarzyna Reszka, PhD, Renata Duchnowska, MD, Janusz Milanowski, MD, Roberto Chiarle, MD, Magda Bienko, PhD, Paweł Krawczyk, MD, Jacek Jassem, MD, Chiara Ambrogio, PhD, Nicola Crosetto, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 12, Pp 100435- (2022)
Introduction: Brain metastases (BM) severely affect the prognosis and quality of life of patients with NSCLC. Recently, molecularly targeted agents were found to have promising activity against BM in patients with NSCLC whose primary tumors carry “
Externí odkaz:
https://doaj.org/article/93978b32039848998a35af7844ee33cf
Autor:
Karolina Kaźmierczak-Siedlecka, Karolina Skonieczna-Żydecka, Theodore Hupp, Renata Duchnowska, Natalia Marek-Trzonkowska, Karol Połom
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Gut microbiota and its association with cancer development/treatment has been intensively studied during the past several years. Currently, there is a growing interest toward next-generation probiotics (NGPs) as therapeutic agents that alter gut micr
Externí odkaz:
https://doaj.org/article/f2a80a96524644fda7fe449795e7e468
Autor:
Jolanta Żok, Michał Bieńkowski, Barbara Radecka, Jan Korniluk, Krzysztof Adamowicz, Renata Duchnowska
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Oxaliplatin-based therapy with FOLFOX-4 or CAPOX administered over 6 months remains the standard adjuvant treatment for stage III colon cancer (CC) patients. However, many patients experience dose reduction or early termination of
Externí odkaz:
https://doaj.org/article/b1e671b827f04f34930b620857b524a5
Publikováno v:
Cancers, Vol 14, Iss 4, p 965 (2022)
Brain metastases are detected in 5% of patients with breast cancer at diagnosis. The rate of brain metastases is higher in HER2-positive and triple-negative breast cancer patients (TNBC). In patients with metastatic breast cancer, the risk of brain m
Externí odkaz:
https://doaj.org/article/aff55096d7f247409303ddb96b637525
Autor:
Joanna Kufel-Grabowska, Anna Niwińska, Barbara S. Radecka, Shan Ali, Tomasz Mandat, Renata Duchnowska
Publikováno v:
Cancers, Vol 14, Iss 5, p 1099 (2022)
Background: Determining the proper therapy is challenging in breast cancer (BC) patients with brain metastases (BM) due to the variability of an individual’s prognosis and the variety of treatment options available. Several prognostic tools for BC
Externí odkaz:
https://doaj.org/article/6947018b824b4ec48b0ed1dab94a68c7
Autor:
Brunilde Gril, Anurag N. Paranjape, Stephan Woditschka, Emily Hua, Emma L. Dolan, Jeffrey Hanson, Xiaolin Wu, Wojciech Kloc, Ewa Izycka-Swieszewska, Renata Duchnowska, Rafał Pęksa, Wojciech Biernat, Jacek Jassem, Naema Nayyar, Priscilla K. Brastianos, O. Morgan Hall, Cody J. Peer, William D. Figg, Gary T. Pauly, Christina Robinson, Simone Difilippantonio, Emilie Bialecki, Philippe Metellus, Joel P. Schneider, Patricia S. Steeg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
When brain metastases form, the blood–brain barrier morphs into the blood–tumor barrier (BTB), surrounded by neuroinflammatory response. Here, the authors show that S1P3 is upregulated in neuroinflammatory response in highly BTB permeable lesions
Externí odkaz:
https://doaj.org/article/69cb9612d00a46d3a48171a71ecd0d7b
Autor:
Renata Duchnowska, Everardo D. Saad, Małgorzata Banaszek, Ewa Pawłowska, Hanna Liberek, Natalia Cichowska-Cwalińska, Jacek Jassem
Publikováno v:
Cancers, Vol 13, Iss 21, p 5306 (2021)
Background: Although brain metastases (BM) affect 5% of all breast cancer patients and 14% of those with metastatic disease, patients with BM are often excluded from participation in clinical trials. We conducted a structured assessment of the contem
Externí odkaz:
https://doaj.org/article/d7ca7631cca749a3884fc7de5c6ff4ce
Publikováno v:
Cancers, Vol 13, Iss 11, p 2645 (2021)
Brain metastasis is a common and devastating clinical entity. Intratumor heterogeneity in brain metastases poses a crucial challenge to precision medicine. However, advances in next-generation sequencing, new insight into the pathophysiology of drive
Externí odkaz:
https://doaj.org/article/7ea4fa9a867545d381128a98a4a13059
Autor:
Rafał Pęksa, Michał Kunc, Marta Popęda, Michał Piątek, Michał Bieńkowski, Jolanta Żok, Anna Starzyńska, Adrian Perdyan, Marek Sowa, Renata Duchnowska, Wojciech Biernat
Publikováno v:
Cancers, Vol 13, Iss 8, p 1750 (2021)
In the current study, we aimed to investigate whether expression of immune checkpoint proteins (V-domain Ig suppressor of T cell activation (VISTA) and programmed death-ligand 1 (PD-L1)) and markers of systemic inflammation could predict progression/
Externí odkaz:
https://doaj.org/article/6d76edc8813648c38fd8088ad06acdaa