Výsledky vyhledávání - "Renata Cunha de Resende"

Akademický článek

Analysis of spironolactone polymorphs in active pharmaceutical ingredients and their effect on tablet dissolution profiles

Autor: Renata Cunha de Resende, Olímpia Maria Martins Santos Viana, Jennifer Tavares Jacon Freitas, Rudy Bonfilio, André Luís Morais Ruela, Magali Benjamim de Araújo

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 52, Iss 4, Pp 613-621

ABSTRACT Spironolactone (SPR) is a steroidal drug administered as a potassium-sparing diuretic for high blood pressure treatment. The drug shows incomplete gastrointestinal absorption due to its poor aqueous solubility. The physicochemical properties

Externí odkaz: https://doaj.org/article/bcaa941258374b0bbca8c0c06664c08f

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Analysis of spironolactone polymorphs in active pharmaceutical ingredients and their effect on tablet dissolution profiles

Autor: Olimpia Maria Martins Santos Viana, Magali Benjamim Araújo, Rudy Bonfilio, Jennifer Tavares Jacon Freitas, André Luís Morais Ruela, Renata Cunha de Resende

Publikováno v: Brazilian Journal of Pharmaceutical Sciences; Vol. 52 No. 4 (2016); 613-621
Brazilian Journal of Pharmaceutical Sciences; Vol. 52 Núm. 4 (2016); 613-621
Brazilian Journal of Pharmaceutical Sciences; v. 52 n. 4 (2016); 613-621
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 52, Iss 4, Pp 613-621
Brazilian Journal of Pharmaceutical Sciences, Volume: 52, Issue: 4, Pages: 613-621, Published: DEC 2016

Spironolactone (SPR) is a steroidal drug administered as a potassium-sparing diuretic for high blood pressure treatment. The drug shows incomplete gastrointestinal absorption due to its poor aqueous solubility. The physicochemical properties of SPR i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc937625d28aac54c2a6fb94ca679b7
https://www.revistas.usp.br/bjps/article/view/128377

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Dissertation/ Thesis

Ocorrência de polimorfismo em matérias-primas de espironolactona e avaliação da influência na qualidade físico-química de comprimidos

Autor: OLIVEIRA, Renata Cunha de Resende

Publikováno v: Biblioteca Digital de Teses e Dissertações da UNIFALUniversidade Federal de AlfenasUNIFAL.

A espironolactona (SPR) é um ingrediente farmacêutico ativo (IFA), com estrutura química esteroidal, que possui atividade diurética sendo utilizada no controle da hipertensão arterial e, também, como agente antiandrogênico. Possui incompleta a

Externí odkaz: https://bdtd.unifal-mg.edu.br:8443/handle/tede/954

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