Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Renata, Tisi"'
Autor:
Simone Spolaor, Mattia Rovetta, Marco S. Nobile, Paolo Cazzaniga, Renata Tisi, Daniela Besozzi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Calcium homeostasis and signaling processes in Saccharomyces cerevisiae, as well as in any eukaryotic organism, depend on various transporters and channels located on both the plasma and intracellular membranes. The activity of these proteins is regu
Externí odkaz:
https://doaj.org/article/bfc503a204064324b7205f598026ea16
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1137-1152 (2020)
Chromosomal DNA double-strand breaks (DSBs) are potentially lethal DNA lesions that pose a significant threat to genome stability and therefore need to be repaired to preserve genome integrity. Eukaryotic cells possess two main mechanisms for repairi
Externí odkaz:
https://doaj.org/article/4dedffd3a5d7458d84af120937dca517
Autor:
Antonio Marsella, Elisa Gobbini, Corinne Cassani, Renata Tisi, Elda Cannavo, Giordano Reginato, Petr Cejka, Maria Pia Longhese
Publikováno v:
Cell Reports, Vol 34, Iss 13, Pp 108906- (2021)
Summary: The Mre11-Rad50-Xrs2 (MRX) complex detects and processes DNA double-strand breaks (DSBs). Its DNA binding and processing activities are regulated by transitions between an ATP-bound state and a post-hydrolysis cutting state that is nucleolyt
Externí odkaz:
https://doaj.org/article/2daadc75ae19488e809716ef636b5a95
Autor:
Renata Tisi, Michela Spinelli, Alessandro Palmioli, Cristina Airoldi, Paolo Cazzaniga, Daniela Besozzi, Marco S. Nobile, Elisa Mazzoleni, Simone Arnhold, Luca De Gioia, Rita Grandori, Francesco Peri, Marco Vanoni, Elena Sacco
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Ras oncoproteins play a crucial role in the onset, maintenance, and progression of the most common and deadly human cancers. Despite extensive research efforts, only a few mutant-specific Ras inhibitors have been reported. We show that cmp4–previou
Externí odkaz:
https://doaj.org/article/12b03615f25342f69a2d6b9a39948924
Publikováno v:
AIMS Molecular Science, Vol 3, Iss 4, Pp 505-549 (2016)
Though fungi show peculiarities in the purposes and specific traits of calcium signaling pathways, the general scheme and the most important players are well conserved if compared to higher eukaryotes. This provides a powerful opportunity either to i
Externí odkaz:
https://doaj.org/article/7b7b1cbba76741f6a65c96895e9211e3
Autor:
Carlo Rinaldi, Paolo Pizzul, Erika Casari, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese
DNA double-strand breaks (DSBs) can be repaired by either homologous recombination (HR) or non-homologous end-joining (NHEJ). NHEJ is induced by the binding to DSBs of the Ku70–Ku80 heterodimer, which acts as a hub for the recruitment of downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca28852cf333276a0bab7c708962f388
https://hdl.handle.net/10281/403662
https://hdl.handle.net/10281/403662
Publikováno v:
Biomolecules, Vol 10, Iss 11, p 1535 (2020)
RAS genes encode signaling proteins, which, in mammalian cells, act as molecular switches regulating critical cellular processes as proliferation, growth, differentiation, survival, motility, and metabolism in response to specific stimuli. Deregulati
Externí odkaz:
https://doaj.org/article/aca0778681944ad1a96146014201bdf4
The Ycx1 protein encoded by the yeast YDL206W gene plays a role in calcium and calcineurin signaling
Autor:
Grace M. Lee, Fangli Weng, Juliana Cranley, Abhinav Rajasekhar, Matthew Stoeckel, Thomas Kane, Renata Tisi, Yuqi Wang
Publikováno v:
Journal of Biological Chemistry. 299:104647
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bea0c33c0345c4059fe05c907ff76f
https://doi.org/10.1016/j.jbc.2023.104647
https://doi.org/10.1016/j.jbc.2023.104647
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1137-1152 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1137-1152 (2020)
Graphical abstract
Chromosomal DNA double-strand breaks (DSBs) are potentially lethal DNA lesions that pose a significant threat to genome stability and therefore need to be repaired to preserve genome integrity. Eukaryotic cells possess two mai
Chromosomal DNA double-strand breaks (DSBs) are potentially lethal DNA lesions that pose a significant threat to genome stability and therefore need to be repaired to preserve genome integrity. Eukaryotic cells possess two mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f386ea780002cbd131fdb18d2754f5
https://doi.org/10.1016/j.csbj.2020.05.013
https://doi.org/10.1016/j.csbj.2020.05.013
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7145
Cannabidiol (CBD) is a non-psychoactive phytocannabinoid that has been discussed for its safety and efficacy in cancer treatments. For this reason, we have inquired into its use on triple-negative human breast cancer. Analyzing the biological effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf966a988aa852283a4a4bec83f41c5
http://hdl.handle.net/10281/386000
http://hdl.handle.net/10281/386000