Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Renat Shaykhiev"'
Autor:
Seyed Babak Mahjour, Kazunori Gomi, Samir Rustam, Phurbu Dolma, Jamuna Krishnan, Olivier Elemento, Frank D’Ovidio, Timothy S. Blackwell, Scott Randell, Renat Shaykhiev
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 154-154 (2019)
OBJECTIVES/SPECIFIC AIMS: The objective of this study was to reconstruct patient-specific distal airway patterns at the tissue- and single-cell resolution and develop personalized distal airway models based on utilization of patient-derived DABCs and
Externí odkaz:
https://doaj.org/article/d6c8c22031494b9c92d7eb944fe8e84f
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 23-23 (2018)
OBJECTIVES/SPECIFIC AIMS: The objective of this study is to develop patient-derived “personalized” organotypic models of human distal airways, in which basal stem cells (BCs) isolated from the pre-/terminal conducting airway region are co-culture
Externí odkaz:
https://doaj.org/article/4005dca4ffdc4c2d830da0fb87057679
Autor:
Dorothy M Ryan, Thomas L Vincent, Jacqueline Salit, Matthew S Walters, Francisco Agosto-Perez, Renat Shaykhiev, Yael Strulovici-Barel, Robert J Downey, Lauren J Buro-Auriemma, Michelle R Staudt, Neil R Hackett, Jason G Mezey, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88051 (2014)
Genome-wide association studies (GWAS) and candidate gene studies have identified a number of risk loci associated with the smoking-related disease COPD, a disorder that originates in the airway epithelium. Since airway basal cell (BC) stem/progenito
Externí odkaz:
https://doaj.org/article/a96e183ed68f47ce9a2a1c5832f7f587
Autor:
Neil R Hackett, Renat Shaykhiev, Matthew S Walters, Rui Wang, Rachel K Zwick, Barbara Ferris, Bradley Witover, Jacqueline Salit, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e18378 (2011)
The human airway epithelium consists of 4 major cell types: ciliated, secretory, columnar and basal cells. During natural turnover and in response to injury, the airway basal cells function as stem/progenitor cells for the other airway cell types. Th
Externí odkaz:
https://doaj.org/article/56a83777d4b04876b333fc6e8e0d30f2
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1393 (2008)
Epithelial cells (ECs) continuously interact with microorganisms and detect their presence via different pattern-recognition receptors (PRRs) including Toll-like receptors (TLRs). Ligation of epithelial TLRs by pathogens is usually associated with th
Externí odkaz:
https://doaj.org/article/87330231a21a486988b2778a8e8fd078
Autor:
Samir Rustam, Yang Hu, Seyed Babak Mahjour, Andre F. Rendeiro, Hiranmayi Ravichandran, Andreacarola Urso, Frank D’Ovidio, Fernando J. Martinez, Nasser K. Altorki, Bradley Richmond, Vasiliy Polosukhin, Jonathan A. Kropski, Timothy S. Blackwell, Scott H. Randell, Olivier Elemento, Renat Shaykhiev
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:1171-1182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7927c6ca4568dc0d33b61230bef9ed9
https://doi.org/10.1164/rccm.202207-1384oc
https://doi.org/10.1164/rccm.202207-1384oc
Autor:
Ronald G. Crystal, Neil R. Hackett, Jason G. Mezey, Renat Shaykhiev, Jacqueline Salit, Tomoya Fukui, Marcus W. Butler
Supplementary Methods and Materials, Supplementary Tables 1-2, Supplemental Figure Legends, Supplementary Figure 1 from Modulation of Cystatin A Expression in Human Airway Epithelium Related to Genotype, Smoking, COPD, and Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb401a3dc027abb27ec4847a0eb9203
https://doi.org/10.1158/0008-5472.22388307
https://doi.org/10.1158/0008-5472.22388307
Autor:
Samir Rustam, Yang Hu, Seyed Babak Mahjour, Scott H. Randell, Andre F. Rendeiro, Hiranmayi Ravichandran, Andreacarola Urso, Frank D’Ovidio, Fernando J. Martinez, Bradley Richmond, Vasiliy Polosukhin, Jonathan A. Kropski, Timothy S. Blackwell, Olivier Elemento, Renat Shaykhiev
In the human lung, terminal bronchioles (TBs), the most distal conducting airways, open to respiratory bronchioles (RBs) that lead to the alveolar region where gas exchange takes place. This transition occurs in pulmonary lobules, lung tissue units s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd005edc830858730a0223779f47a4e1
https://doi.org/10.1101/2022.03.16.484543
https://doi.org/10.1101/2022.03.16.484543
Autor:
Junbum Kim, Samir Rustam, Juan Miguel Mosquera, Scott H. Randell, Renat Shaykhiev, André F. Rendeiro, Olivier Elemento
Publikováno v:
Nature methods. 19(12)
Multiplexed imaging and spatial transcriptomics enable highly resolved spatial characterization of cellular phenotypes, but still largely depend on laborious manual annotation to understand higher-order patterns of tissue organization. As a result, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7043b0e1393c420787b61c5c72ea08e1
https://pubmed.ncbi.nlm.nih.gov/36414761
https://pubmed.ncbi.nlm.nih.gov/36414761
Autor:
Renat Shaykhiev
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Airway basal cells are crucial for regeneration of the human lung airway epithelium and are believed to be important contributors to chronic obstructive pulmonary disease (COPD) and other lung disorders. To reveal how basal cells contribute to diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72cde3f922b185397e58e9a59286c7a8
https://doi.org/10.1165/rcmb.2021-0150ed
https://doi.org/10.1165/rcmb.2021-0150ed