Výsledky vyhledávání - "Renan F. Domingos"

Akademický článek

Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro.

Autor: Rosane Oliveira, Renan F Domingos, Gabriela H Siqueira, Luis G Fernandes, Natalie M Souza, Monica L Vieira, Zenaide M de Morais, Silvio A Vasconcellos, Ana L T O Nascimento

Publikováno v: PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2396 (2013)

We report in this work that Leptospira strains, virulent L. interrogans serovar Copenhageni, attenuated L. interrogans serovar Copenhageni and saprophytic L. biflexa serovar Patoc are capable of binding fibrinogen (Fg). The interaction of leptospires

Externí odkaz: https://doaj.org/article/dab803c49ceb4b4eac559d6b33b35e2d

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Leptospiral extracellular matrix adhesins as mediators of pathogen-host interactions

Autor: Natalie M. Souza, Gabriela H. Siqueira, Ana L. T. O. Nascimento, Monica L. Vieira, Marina V. Atzingen, Aline F. Teixeira, Renan F. Domingos, Luis G. V. Fernandes, Rosane Oliveira

Publikováno v: FEMS Microbiology Letters. 352:129-139

Leptospirosis is been considered an important infectious disease that affects humans and animals worldwide. This review summarizes our current knowledge of bacterial attachment to extracellular matrix (ECM) components and discusses the possible role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210a8dcb150b5433c9241a9c1e0e13fd
https://doi.org/10.1111/1574-6968.12349

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Novel Leptospira interrogans protein Lsa32 is expressed during infection and binds laminin and plasminogen

Autor: Silvio Arruda Vasconcellos, Zenaide Maria de Morais, Eliete Caló Romero, Luis G. V. Fernandes, Renan F. Domingos, Ana L. T. O. Nascimento

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Pathogenic Leptospira is the aetiological agent of leptospirosis, a life-threatening disease of human and veterinary concern. The quest for novel antigens that could mediate host-pathogen interactions is being pursued. Owing to their location, these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b1c054ad241ce04c2eb1fa962c05b2
https://pubmed.ncbi.nlm.nih.gov/25627443

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Characterization of two proteins of Leptospira interrogans in the pathogenesis of leptospirosis

Autor: Renan F. Domingos

Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

O sequenciamento da L. interrogans sorovar Copenhageni e as análises bioinformáticas permitiram a identificação de candidatos vacinais e fatores de virulência. Foram selecionados dois genes, LIC11834 e LIC12253, que foram submetidos a ensaios de

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Intermediate and C-terminal regions of leptospiral adhesin Lsa66 are responsible for binding with plasminogen and extracellular matrix components

Autor: Eliete Caló Romero, Rosane Oliveira, Silvio Arruda Vasconcellos, Zenaide Maria de Morais, Ivy J. Alves, Renan F. Domingos, Ana L. T. O. Nascimento

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Leptospirosis, a worldwide zoonotic infection, is an important human and veterinary health problem. We have previously identified a leptospiral multipurpose adhesin, Lsa66, capable of binding extracellular matrix (ECM) components and plasminogen (PLG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396fcab947c398ecebd839e396e9bb1e

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Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro

Autor: Renan F. Domingos, Zenaide Maria de Morais, Rosane Oliveira, Silvio Arruda Vasconcellos, Ana L. T. O. Nascimento, Luis G. V. Fernandes, Gabriela H. Siqueira, Monica L. Vieira, Natalie M. Souza

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2396 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6418eeb080ba097b0beed36e74994a

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Evaluation of immunoprotective activity of six leptospiral proteins in the hamster model of leptospirosis

Autor: Monica L. Vieira, Amane Paldês Gonçales, Zenaide Maria de Morais, Renan F. Domingos, Rosane Oliveira, Ana L. T. O. Nascimento, Renata S. Mendes, Aline T Barros, Silvio Arruda Vasconcellos, Marina V. Atzingen

Publikováno v: The Open Microbiology Journal
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira. The whole-genome sequence of L. in- terrogans serovar Copenhageni together with bioinformatics tools represent a great opportunity to search for novel anti- gen candidates that co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df211f9210033846e254d2d48a8ca048
https://pubmed.ncbi.nlm.nih.gov/23173023

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Plasminogen Binding Proteins and Plasmin Generation on the Surface of Leptospira spp.: The Contribution to the Bacteria-Host Interactions

Autor: Marina V. Atzingen, Monica L. Vieira, Rosane Oliveira, Silvio Arruda Vasconcellos, Ana L. T. O. Nascimento, Renata S. Mendes, Renan F. Domingos

Publikováno v: Journal of Biomedicine and Biotechnology, Vol 2012 (2012)
Journal of Biomedicine and Biotechnology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Leptospirosis is considered a neglected infectious disease of human and veterinary concern. Although extensive investigations on host-pathogen interactions have been pursued by several research groups, mechanisms of infection, invasion and persistenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db649c7d2e7b9d5e558555118bab5cc
https://doaj.org/article/95129a44dae64ccc851e1fdf0425a7aa

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'Features of two proteins of Leptospira interrogans with potential role in host-pathogen interactions'

Autor: Zenaide Maria de Morais, Renan F. Domingos, Amane Paldês Gonçales, Eliete Caló Romero, Silvio Arruda Vasconcellos, Monica L. Vieira, Ana L. T. O. Nascimento

Publikováno v: BMC Microbiology, Vol 12, Iss 1, p 50 (2012)
BMC Microbiology

Background Leptospirosis is considered a re-emerging infectious disease caused by pathogenic spirochaetes of the genus Leptospira. Pathogenic leptospires have the ability to survive and disseminate to multiple organs after penetrating the host. Lepto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117093cb036fee6f9d7efcfec842e0e7

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