Výsledky vyhledávání - "Renan Canibal Pires"

Akademický článek

Evaluation of Sexual Dimorphism in the Efficacy and Safety of Simvastatin/Atorvastatin Therapy in a Southern Brazilian Cohort

Autor: Lisiane Smiderle, Luciana O. Lima, Mara Helena Hutz, Cézar Roberto Van der Sand, Luiz Carlos Van der Sand, Maria Elvira Wagner Ferreira, Renan Canibal Pires, Silvana Almeida, Marilu Fiegenbaum

Publikováno v: Arquivos Brasileiros de Cardiologia, Vol 103, Iss 1, Pp 33-40 (2014)

Background: Dyslipidemia is the primary risk factor for cardiovascular disease, and statins have been effective in controlling lipid levels. Sex differences in the pharmacokinetics and pharmacodynamics of statins contribute to interindividual variati

Externí odkaz: https://doaj.org/article/8503df63ee834ae2acea732a17c90c82

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Akademický článek

Emprego de altas doses de amiodarona via oral na reversão da fibrilação atrial no pós-operatório de cirurgia cardíaca High dose amiodarone for the reversion of atrial fibrillation during the postoperative period of cardiac surgery

Autor: João Carlos Vieira da Costa Guaragna, Valério Martins, Tatiana Marlowe Cunha Brunini, José Luis Linhatti, Fábio Branco de Araújo Brauner, Renan Canibal Pires, Luiz Carlos Bodanese

Publikováno v: Arquivos Brasileiros de Cardiologia, Vol 69, Iss 6, Pp 401-405 (1997)

OBJETIVO: Relatar a experiência no emprego de altas doses de amiodarona via oral (1800mg/d) na reversão da fibrilação atrial (FA) em pacientes submetidos à cirurgia cardíaca. MÉTODOS: Analisados, retrospectivamente, 80 pacientes que apresentar

Externí odkaz: https://doaj.org/article/20d4a6af8c39482692bdb97843cd4d83

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Influência de polimorfismos nos genes PPARA, RXRA, NR1I2 e NR1I3 na eficácia hipolipemiante e na segurança da terapia com estatinas

Autor: Maria Elvira Wagner Ferreira, Renan Canibal Pires, Silvana Almeida, Luciana O. Lima, Marilu Fiegenbaum, Cézar Roberto Van der Sand, Mara H. Hutz, Estela M. Bruxel, Luiz Carlos Van der Sand

Publikováno v: Arquivos Brasileiros de Endocrinologia & Metabologia v.57 n.7 2013
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
Arquivos Brasileiros de Endocrinologia & Metabologia, Volume: 57, Issue: 7, Pages: 513-519, Published: OCT 2013

OBJECTIVE: The aim of the present study was investigate the association between six genetic variants in the nuclear receptor genes PPARA, RXRA, NR1I2 and NR1I3 and the lipid-lowering efficacy and safety of statin therapy. SUBJECTS AND METHODS: The st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d706a050c9283f37d9ced84d669084
https://doi.org/10.1590/s0004-27302013000700003

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ESR1 polymorphisms and statin therapy: a sex-specific approach

Autor: Maria Elvira Wagner Ferreira, Marilu Fiegenbaum, L C Van der Sand, Renan Canibal Pires, C R Van der Sand, Silvana Almeida, Lisiane Smiderle, Mara H. Hutz

Publikováno v: Europe PubMed Central

Lipid-lowering therapy has shown a high degree of variability in clinical response and there is evidence that the variability in drug response between individuals is due to genetic factors. Thirteen single nucleotide polymorphisms (SNPs) within the E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e660f5db5a7e617f02f8dcfee5e02162
https://pubmed.ncbi.nlm.nih.gov/26302681

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PON1 polymorphisms are predictors of ability to attain HDL-C goals in statin-treated patients

Autor: Maria Elvira Wagner Ferreira, Renan Canibal Pires, Jéssica Aguiar de Souza, Luciana O. Lima, Luiz Carlos Van der Sand, Cézar Roberto Van der Sand, Angelica Menin, Marilu Fiegenbaum, Mara H. Hutz, Silvana Almeida, Lisiane Smiderle

Publikováno v: Clinical biochemistry. 48(16-17)

Objectives PON1 plays an important role in inhibiting LDL-C oxidation, which reduces atherosclerosis and cardiovascular disease. Elevated PON1 activity or levels may contribute to increased HDL-C levels, but controversy exists over the hypothesis tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54865bf9113ac24f287f5c3a97ad7ca4
https://pubmed.ncbi.nlm.nih.gov/26079344

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Pharmacogenetic study of apolipoprotein E, cholesteryl ester transfer protein and hepatic lipase genes and simvastatin therapy in Brazilian subjects

Autor: Marilu Fiegenbaum, Cézar Roberto Van der Sand, Renan Canibal Pires, Maria Elvira Wagner Ferreira, Fabiano Roldao Silveira, Luiz Carlos Van der Sand, Mara H. Hutz

Publikováno v: Clinica Chimica Acta. 362:182-188

Background In recent years, one of the focuses of genetic investigation in cardiology has been to identify the genetic factors associated with variable response to statin treatment. Polymorphisms in apolipoprotein E (APOE), cholesteryl ester transfer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b737266d77c7827ce567e88cd10cdb8
https://doi.org/10.1016/j.cccn.2005.06.005

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The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment

Autor: Renan Canibal Pires, Mara H. Hutz, Maria Elvira Wagner Ferreira, Luiz Carlos Van der Sand, Fabiano Roldao Silveira, Cézar Roberto Van der Sand, Marilu Fiegenbaum

Publikováno v: Clinical Pharmacology & Therapeutics. 78:551-558

Our objective was to investigate the interactions between common polymorphisms in ABCB1, CYP3A4, and CYP3A5 genes and the lipid-lowering efficacy and safety of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor simvastatin.One hundred sixt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d10051202021f40b04f47994097e145
https://doi.org/10.1016/j.clpt.2005.08.003

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Determinants of variable response to simvastatin treatment: the role of common variants of SCAP, SREBF-1a and SREBF-2 genes

Autor: Renan Canibal Pires, Maria Elvira Wagner Ferreira, Fabiano Roldao Silveira, Mara H. Hutz, L C Van der Sand, Marilu Fiegenbaum, C R Van der Sand

Publikováno v: The Pharmacogenomics Journal. 5:359-364

We investigated the effect of single-nucleotide polymorphisms in sterol regulatory element-binding factors-1a and -2 (SREBF-1a and SREBF-2) and SREBF cleavage-activating protein (SCAP) genes on lipid-lowering response to simvastatin. In all, 146 hype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4a07900442a9dd823dc442c4d7aed1
https://doi.org/10.1038/sj.tpj.6500334

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Evaluation of Sexual Dimorphism in the Efficacy and Safety of Simvastatin/Atorvastatin Therapy in a Southern Brazilian Cohort

Autor: Marilu Fiegenbaum, Silvana Almeida, Renan Canibal Pires, Luciana O. Lima, Luiz Carlos Van der Sand, Cézar Roberto Van der Sand, Maria Elvira Wagner Ferreira, Mara H. Hutz, Lisiane Smiderle

Publikováno v: Arquivos Brasileiros de Cardiologia, Vol 103, Iss 1, Pp 33-40 (2014)
Arquivos Brasileiros de Cardiologia
Arquivos Brasileiros de Cardiologia v.103 n.1 2014
Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8f2a4b2638b9d19e0391fc260a854f
https://doi.org/10.5935/abc.20140085

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Emprego de altas doses de amiodarona via oral na reversão da fibrilação atrial no pós-operatório de cirurgia cardíaca

Autor: Valério Martins, Luiz Carlos Bodanese, Renan Canibal Pires, Fábio Branco de Araújo Brauner, Tatiana Marlowe Cunha Brunini, José Luis Linhatti, João Carlos Vieira da Costa Guaragna

Publikováno v: Arquivos Brasileiros de Cardiologia v.69 n.6 1997
Arquivos Brasileiros de Cardiologia
Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC
Arquivos Brasileiros de Cardiologia, Volume: 69, Issue: 6, Pages: 401-405, Published: DEC 1997

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6560cc264d226faf1c5437602af40dd7
https://doi.org/10.1590/s0066-782x1997001200007

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