Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC

Autor: Johannes Loffing, Dominique Loffing-Cueni, Denise V. Kratschmar, Christina Schnoz, Sandra Moser, Alex Odermatt

Publikováno v: Pflugers Archiv

The renal distal convoluted tubule (DCT) is critical for the fine-tuning of urinary ion excretion and the control of blood pressure. Ion transport along the DCT is tightly controlled by posttranscriptional mechanisms including a complex interplay of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ff553d8a385117c20f937280b5696f
http://europepmc.org/articles/PMC7782375

KLHL3-dependent WNK4 degradation affected by potassium through the neddylation and autophagy pathway.

Autor: Ying, Siqi, Guo, Qin, Zhang, Chong

Publikováno v: BMC Nephrology; 7/22/2023, Vol. 24 Issue 1, p1-8, 8p

Inwardly rectifying K⁺ channels 4.1 and 5.1 (Kir4.1/Kir5.1) in the renal distal nephron.

Autor: Wen-Hui Wang, Dao-Hong Lin

Publikováno v: American Journal of Physiology: Cell Physiology; Aug2022, Vol. 323 Issue 2, pC277-C288, 12p

Extracellular K⁺ rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl⁻-dependent and independent mechanisms.

Autor: Penton, David, Czogalla, Jan, Wengi, Agnieszka, Himmerkus, Nina, Loffing‐Cueni, Dominique, Carrel, Monique, Rajaram, Renuga Devi, Staub, Olivier, Bleich, Markus, Schweda, Frank, Loffing, Johannes

Publikováno v: Journal of Physiology; Nov2016, Vol. 594 Issue 21, p6319-6331, 13p

Transcription factor HNF1β regulates expression of the calcium-sensing receptor in the thick ascending limb of the kidney.

Autor: Kompatscher, Andreas, de Baaij, Jeroen H. F., Aboudehen, Karam, Farahani, Shayan, van Son, Lex H. J., Milatz, Susanne, Himmerkus, Nina, Veenstra, Gertjan C., Bindels, René J. M., Hoenderop, Joost G. J.

Publikováno v: American Journal of Physiology: Renal Physiology; Jul2018, Vol. 315 Issue 1, pF27-F35, 9p, 1 Black and White Photograph, 2 Charts, 3 Graphs