Výsledky vyhledávání - "Ren-Xiao Sun"

MBR rearrangement and P-glycoprotein expression are not independent prognostic factors like p53 protein in malignant lymphoma

Autor: Bernard Klein, J. Coste, E. Legouffe, T. Rousset, Thierry Rème, C. Segara, Ren-Xiao Sun, M. Fabbro, Jean-François Rossi

Publikováno v: Clinical & Laboratory Haematology. 20:87-94

Non-Hodgkin's lymphomas (NHL) are B-cell malignancies which generally present molecular abnormalities, such as bcl-2 translocation t(14; 18) predominantly in the follicular subgroup. Other molecular events have been described in NHL, including p53 ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c9b7fac18d0b09f8279f0d8922b5a4
https://doi.org/10.1046/j.1365-2257.1998.00090.x

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Human interleukin-6 receptor super-antagonists with high potency and wide spectrum on multiple myeloma cells

Autor: Elisabetta Sporeno, Gennaro Ciliberto, Armin Lahm, Carlo Toniatti, Ren Xiao Sun, Laura Ciapponi, Giacomo Paonessa, Kari Pulkki, Bernard Klein, Rocco Savino, Andrea Cabibbo

Publikováno v: Blood. 87:4510-4519

Interleukin-6 (IL-6) is the major growth factor for myeloma cells and is believed to participate in the pathogenesis of chronic autoimmune diseases and postmenopausal osteoporosis. IL-6 has been recently shown to possess three topologically distinct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::474577b3639108930719af7368ac313d
https://doi.org/10.1182/blood.v87.11.4510.bloodjournal87114510

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Large scale and clinical grade purification of syndecan-1 plus malignant plasma cells

Autor: John Wijdenes, Catherine Hertog, Jean-François Rossi, Bernard Klein, Jean Brochier, Zhao-Yang Lu, Ren-Xiao Sun

Publikováno v: Journal of Immunological Methods
Journal of Immunological Methods, Elsevier, 1997, 205 (1), pp.73--79. ⟨10.1016/S0022-1759(97)00056-2⟩

For cancer immunotherapy, it is usually necessary to obtain a large number of tumor cells from patients. We have previously reported that syndecan-1 is present only on malignant plasma cells in samples from patients with multiple myelomatosis. We rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda4321e5670c78f7c6c3526a7f54b94
https://hal.archives-ouvertes.fr/hal-02195789

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Specific inhibition of IL-6 signalling with monoclonal antibodies against the gp130 receptor

Autor: Jean Brochier, Jean-Claude Mani, Bernard Klein, Nathalie Cotte, J. P. Gaillard, Ren-Xiao Sun, Janny Liautard

Publikováno v: Cytokine
Cytokine, Elsevier, 1997, 9 (4), pp.233--241
Cytokine, Elsevier, 1997, 9 (4), pp.233--241. ⟨10.1006/cyto.1996.0159⟩

A family of cytokines [IL-6, IL-11, oncostatin M (OM), leukaemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF) and cardiotrophin-1] involved in various inflammatory or tumoral diseases share the same gp130 signal transducer chain. The c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fe3e1023ea442b7ca2d0f3e09ce7c5
https://hal.archives-ouvertes.fr/hal-02194550

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A plasmocyte selective monoclonal antibody (B-B4) recognizes syndecan-1

Autor: Jean-Michel Dore, Patrick Laurent, Ren-Xiao Sun, Natalio Vita, Jacob Post, Bernard Klein, John Wijdenes, Florence Morard, Wim C. Vooijs, Claude Clement

Publikováno v: British journal of haematology. 94(2)

We developed a new monoclonal antibody. B-B4, which specifically identifies human plasma cells. It strongly reacts with all multiple myeloma cell lines and with malignant plasma cells of all tumour samples of the multiple myeloma patients tested. B-B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001589aa70d39d06fb6a6f9ab53895dc
https://pubmed.ncbi.nlm.nih.gov/9359531

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