Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ren-Kui Bai"'
Supplementary Tables 1-3 from Mitochondrial Genetic Background Modifies Breast Cancer Risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442cecb26de1daf1115feeafa8bf6c39
https://doi.org/10.1158/0008-5472.22366743.v1
https://doi.org/10.1158/0008-5472.22366743.v1
Inefficient mitochondrial electron transport chain (ETC) function has been implicated in the vicious cycle of reactive oxygen species (ROS) production that may predispose an individual to late onset diseases, such as diabetes, hypertension, and cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe666315c5572caf0cd69c06c5b0e13
https://doi.org/10.1158/0008-5472.c.6495267.v1
https://doi.org/10.1158/0008-5472.c.6495267.v1
Publikováno v:
Journal of Human Genetics. Oct2008, Vol. 53 Issue 10, p924-928. 5p. 5 Charts.
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797:29-37
Somatic mitochondrial DNA alterations have been found in all types of cancer. To better understand the role of mitochondria and their involvement in the pathogenic mechanisms of cancer development, the effects of cancer mitochondria were investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41e71802a7f4d3d75a3593f5045a144
https://doi.org/10.1016/j.bbabio.2009.07.008
https://doi.org/10.1016/j.bbabio.2009.07.008
Publikováno v:
Muscle & Nerve. 34:437-443
Mutations in the mitochondrial genome contribute to the pathophysiology of many neuromuscular diseases. Recently there has been an increased appreciation of the role of mitochondrial DNA (mtDNA) mutations in the etiology of exercise intolerance. Usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358db92b5f6b44a3bd2ea55aae2c289f
https://doi.org/10.1002/mus.20605
https://doi.org/10.1002/mus.20605
Publikováno v:
Annals of the New York Academy of Sciences. 1042:36-47
Hearing loss is a common clinical feature in mitochondria-syndrome disorders. The underlining molecular etiology of hearing loss has not been fully investigated. In this study, 83 patients with mitochondrial syndromic hearing loss were evaluated clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a0b2c74f59e41ba70351e1f546253b
https://doi.org/10.1196/annals.1338.004
https://doi.org/10.1196/annals.1338.004
Autor:
David R. Sibley, Zhiwei Yang, Ren Kui Bai, Laureano D. Asico, John E. Jones, Robin A. Felder, Pedro A. Jose, Peiying Yu, Zheng Wang
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H55-H61
D1-like receptors have been reported to decrease oxidative stress in vascular smooth muscle cells by decreasing phospholipase D (PLD) activity. However, the PLD isoform regulated by D1-like receptors (D1or D5) and whether abnormal regulation of PLD b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df1c7e1294e9eb9183c9a0d6c25821e
https://doi.org/10.1152/ajpheart.00627.2004
https://doi.org/10.1152/ajpheart.00627.2004
Autor:
Ren-Kui Bai, Lee-Jun C. Wong
Publikováno v:
Clinical Chemistry. 50:996-1001
Background: The A3243G mitochondrial tRNA leu(UUR) point mutation causes mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome, the most common mitochondrial DNA (mtDNA) disorder, and is also found in pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4379729f8f85f46ce0865a9b07257d1e
https://doi.org/10.1373/clinchem.2004.031153
https://doi.org/10.1373/clinchem.2004.031153
Publikováno v:
Annals of the New York Academy of Sciences. 1011:304-309
Molecular diagnosis of mitochondrial DNA disorder is usually focused on point mutations and large deletions. In the absence of detectable mtDNA mutations, abnormal amounts of mtDNA, either depletion or elevation, can be indicative of mitochondrial dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d6628ae8d57ce85981d5eca4ffdf5c
https://doi.org/10.1196/annals.1293.029
https://doi.org/10.1196/annals.1293.029
Publikováno v:
Clinical Chemistry. 48:1901-1912
Background: Definitive molecular diagnosis of mitochondrial disorders has been greatly hindered by the tremendous clinical and genetic heterogeneity, the heteroplasmic condition of pathogenic mutations, and the presence of numerous homoplasmic mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cace39dec6d4a02421696d018081ac
https://doi.org/10.1093/clinchem/48.11.1901
https://doi.org/10.1093/clinchem/48.11.1901