Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ren Wen Han"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Understanding how distinct functional circuits are coordinated to fine-tune mood and behavior is of fundamental importance. Here, we observe that within the dense projections from basolateral amygdala (BLA) to bed nucleus of stria terminalis
Externí odkaz:
https://doaj.org/article/7668cc6efd974293aac7ee82c59d33cc
Autor:
Ren-wen Han, Zhi-peng Liu, Hong-ru Lin, Ao-wen Tian, Yun-fei Xiao, Jie Wei, Ke-yu Deng, Bing-xing Pan, Hong-bo Xin
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-7 (2020)
Abstract Calstabin2, also named FK506 binding protein 12.6 (FKBP12.6), is a subunit of ryanodine receptor subtype 2 (RyR2) macromolecular complex, an intracellular calcium channel. Studies from our and other’s lab have shown that hippocampal calsta
Externí odkaz:
https://doaj.org/article/a16a43e02bd74b9195372a3acda7695d
Publikováno v:
Neurobiology of Learning and Memory. 162:9-14
Nociceptin/Orphanin FQ (N/OFQ) plays an important role in the regulation of spatial, fear and recognition memories. N/OFQ receptors are highly distributed in the perirhinal cortex, which is a key brain area involved in modulating novel object recogni
Autor:
Dalei Zhang, Jinglei Wang, Jia-Xiang Chen, Fu-Yan Liu, Qing Deng, Yong-ling Liu, Ren-wen Han, Bing Wu, Jie Wei
Publikováno v:
Brain Research Bulletin. 146:112-123
Ghrelin(1–7)-NH2 is the active N-terminal hepta-peptide of ghrelin as an agonist at the ghrelin receptor GHS-R1α. The biological functions of ghrelin(1–7)-NH2 have not been well investigated. Therefore in this study, we were interested in explor
Autor:
Yun-Fei Xiao, Jie Wei, Ke-Yu Deng, Ao-wen Tian, Zhi-Peng Liu, Bing-Xing Pan, Hongbo Xin, Hongru Lin, Ren-wen Han
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-7 (2020)
Molecular Brain
Molecular Brain
Calstabin2, also named FK506 binding protein 12.6 (FKBP12.6), is a subunit of ryanodine receptor subtype 2 (RyR2) macromolecular complex, an intracellular calcium channel. Studies from our and other’s lab have shown that hippocampal calstabin2 regu
Autor:
Bao-Ming Li, Qing-Hai He, Tian-Ming Gao, Jun-Yu Zhang, Jin Zhou, Han-Qing Pan, Ren-Wen Han, Bing-Xing Pan, Xiao-Ping Ying, Wen-Bing Chen, Ye He, Xiao-Bin Xu, Wenhua Zhang, Zhi-Peng Liu
Publikováno v:
Biological Psychiatry. 81:990-1002
Background Maintaining gamma-aminobutyric acidergic (GABAergic) inhibition in the amygdala within a physiological range is critical for the appropriate expression of emotions such as fear and anxiety. The synaptic GABA type A receptor (GABA A R) is g
Autor:
Pei Wang, Rui Wang, Xue Hongxiang, Min Chang, Meixing Li, Ren-wen Han, JinHong Jiang, Peng Yali, P.J. Zhang
Publikováno v:
Peptides. 71:196-201
Neuropeptide S (NPS), the endogenous ligand of NPS receptor (NPSR), was reported to be involved in the regulation of arousal, anxiety, locomotion, learning and memory. The basal ganglia play a crucial role in regulating of locomotion-related behavior
Autor:
Peng Yali, Ke-yu Deng, Rui-san Zhang, Pei Wang, Rui Wang, Min Chang, Hong-jiao Xu, Ren-wen Han
Publikováno v:
Neurobiology of Learning and Memory. 107:32-36
The noradrenergic activity in the basolateral amygdala (BLA) was reported to be involved in the regulation of object recognition memory. As the BLA expresses high density of receptors for Neuropeptide S (NPS), we investigated whether the BLA is invol
Publikováno v:
Neuropharmacology. 70:261-267
Neuropeptide S (NPS), the endogenous ligand of NPSR, has been shown to promote arousal and anxiolytic-like effects. According to the predominant distribution of NPSR in brain tissues associated with learning and memory, NPS has been reported to modul
Autor:
Rui Wang, Rui San Zhang, Min Chang, Yifan Han, Sheng Quan Hu, Chung Lit Choi, Peng Yali, Pei Wang, Ming Yin, Ren Wen Han
Publikováno v:
Brain Research. 1470:59-68
Our previous reports indicated that bis(propyl)-cognitin (B3C) and bis(heptyl)-cognitin (B7C), as novel dimers derived from tacrine, may be potential multifunctional drugs for treating Alzheimer's disease. There is little knowledge on the cognitive f