Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Ren‐Yu Zhang"'
Autor:
Lin He, Hao Li, Can Li, Ze‐Kun Liu, Meng Lu, Ren‐Yu Zhang, Dong Wu, Ding Wei, Jie Shao, Man Liu, Hao‐Lin Wei, Cong Zhang, Zhe Wang, Ling‐Min Kong, Zhi‐Nan Chen, Huijie Bian
Publikováno v:
Cancer Communications, Vol 43, Iss 9, Pp 981-1002 (2023)
Abstract Background The mechanism of hepatitis B virus (HBV)‐induced carcinogenesis remains an area of interest. The accumulation of hepatitis B surface antigen in the endoplasmic reticulum (ER) of hepatocytes stimulates persistent ER stress. Activ
Externí odkaz:
https://doaj.org/article/1897dcbb12144a1ba7353c0c89c8b9a8
Autor:
Ze-Kun Liu, Can Li, Ren-Yu Zhang, Ding Wei, Yu-Kui Shang, Yu-Le Yong, Ling-Min Kong, Nai-Shan Zheng, Ke Liu, Meng Lu, Man Liu, Cai-Xia Hu, Xiao-Zhen Yang, Zhi-Nan Chen, Huijie Bian
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-18 (2021)
Abstract Background Somatic mutations are involved in hepatocellular carcinoma (HCC) progression, but the genetic mechanism associated to hepatocarcinogenesis remains poorly understood. We report that Eyes absent homolog 2 (EYA2) suppresses the HCC p
Externí odkaz:
https://doaj.org/article/45fb30bc5bea4924866c9fcdb113aeed
Autor:
Ren-Yu Zhang, Ze-Kun Liu, Ding Wei, Yu-Le Yong, Peng Lin, Hao Li, Man Liu, Nai-Shan Zheng, Ke Liu, Cai-Xia Hu, Xiao-Zhen Yang, Zhi-Nan Chen, Huijie Bian
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Genomic sequencing analysis of tumors provides potential molecular therapeutic targets for precision medicine. However, identifying a key driver gene or mutation that can be used for hepatocellular carcinoma (HCC) treatment remains difficult
Externí odkaz:
https://doaj.org/article/bc676c8f7013446d8d3e1aa50fd1129f
Autor:
Ze-Kun Liu, Ke-Fei Wu, Ren-Yu Zhang, Ling-Min Kong, Run-Ze Shang, Jian-Jun Lv, Can Li, Meng Lu, Yu-Le Yong, Cong Zhang, Nai-Shan Zheng, Yan-Hong Li, Zhi-Nan Chen, Huijie Bian, Ding Wei
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pyroptosis is an inflammatory form of programmed cell death that is involved in various cancers, including hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) were recently verified as crucial mediators in the regulation of pyroptosis. How
Externí odkaz:
https://doaj.org/article/eb40d2d652b0417b8487c1678422026d
Autor:
Jian-Jun Lv, Hao Wang, Hong-Yong Cui, Ze-Kun Liu, Ren-Yu Zhang, Meng Lu, Can Li, Yu-Le Yong, Man Liu, Hai Zhang, Tian-Jiao Zhang, Kun Zhang, Gang Li, Gang Nan, Cong Zhang, Shuang-Ping Guo, Ling Wang, Zhi-Nan Chen, Huijie Bian
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
The persistence of macrophage-derived foam cells in the artery wall fuels atherosclerosis development. However, the mechanism of foam cell formation regulation remains elusive. We are committed to determining the role that CD147 might play in macroph
Externí odkaz:
https://doaj.org/article/48f07998a1b74a25a428cdba0a6ad646
Autor:
Ren-Yu Zhang, Ding Wei, Ze-Kun Liu, Yu-Le Yong, Wei Wei, Zhi-Yun Zhang, Jian-Jun Lv, Zhao Zhang, Zhi-Nan Chen, Huijie Bian
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Chimeric antigen receptor T cell (CAR-T) therapy to hematological malignancies has demonstrated tremendous clinical outcomes. However, the therapeutic efficacy of CAR-T cells in solid tumors remains limited due to the scarcity of tumor-specific antig
Externí odkaz:
https://doaj.org/article/e7ba422ef56942babe180b4104e8dfbd
Publikováno v:
PeerJ, Vol 7, p e7436 (2019)
Hepatocellular carcinoma (HCC) is one of the most heterogeneous malignant cancers with no effective targets and treatments. However, the molecular pathogenesis of HCC remains largely uncertain. The aims of our study were to find crucial genes involve
Externí odkaz:
https://doaj.org/article/a7ec217e41374429987b6b08a7c90cee
Autor:
Nai-Shan Zheng, Xiang-Yu Zhao, Ding Wei, Jin-Lin Miao, Ze-Kun Liu, Yu-Le Yong, Ren-Yu Zhang, Yi-Xiao Guo, Lin He, Bin Wang, Xiu-Xuan Sun, Hai-Jiao Yang, Tian-Jiao Zhang, Qian He, Xiao-Min Li, Hai Zhang, Rong Hou, Peng Lin, Ying-Ming Xu, Xiao-Jun Huang, Zhi-Nan Chen, Huijie Bian
Publikováno v:
Cancer letters. 542
T cell acute lymphoblastic leukemia (T-ALL) is invasive and heterogeneous, and existing therapies are sometimes unsuccessful. Chimeric antigen receptor (CAR) T cell therapy is a breakthrough tumor treatment method, particularly for B cell acute lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d7b8d38674a9451a9898e6188003f3
https://pubmed.ncbi.nlm.nih.gov/35659513
https://pubmed.ncbi.nlm.nih.gov/35659513
Autor:
Huijie Bian, Yu-Le Yong, Ding Wei, Jiao Wu, Ren-Yu Zhang, Ze-Kun Liu, Zhi-Nan Chen, Zhi-Yun Zhang, Can Li, Yu-Kui Shang
Publikováno v:
The Journal of Pathology. 249:255-267
The γ-secretase complex is a presenilin-dependent aspartyl protease involved in the intramembranous cleavage of various type I transmembrane proteins. As a type I transmembrane protein, CD147 is highly expressed in hepatoma cells and promotes cell p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e93d4248458da87cc39241cd991770f
https://doi.org/10.1002/path.5316
https://doi.org/10.1002/path.5316
Autor:
Mengyao Zhang, Huijie Bian, Shiyou Li, Dan Luo, You-Wen He, Zhinan Chen, Jun Jiang, Xiaodong Wu, Zhao Zhang, Ren-Yu Zhang
Publikováno v:
Frontiers of Medicine. 13:57-68
Lung cancer is the most common incident cancer and the leading cause of cancer death. In recent years, the development of tumor immunotherapy especially chimeric antigen receptor T (CAR-T) cell has shown a promising future. Epidermal growth factor re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dab6ae0e229ebdbbdd0157da00c6a4a
https://doi.org/10.1007/s11684-019-0683-y
https://doi.org/10.1007/s11684-019-0683-y