Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Renée V. Hoch"'
Publikováno v:
Cell Reports, Vol 12, Iss 3, Pp 482-494 (2015)
The Otx2 homeodomain transcription factor is essential for gastrulation and early neural development. We generated Otx2 conditional knockout (cKO) mice to investigate its roles in telencephalon development after neurulation (approximately embryonic d
Externí odkaz:
https://doaj.org/article/17bb01aabbef49c2b5525cf4b82dede2
Autor:
Aleksandar Rajkovic, Gabriel L. McKinsey, Leila Taher, Olga Golonzhka, Renée V. Hoch, Magnus Sandberg, Luis Puelles, Daniel Vogt, Hongkui Zeng, John L.R. Rubenstein, Dongji Zhang, Carol Kim, José Luis Ferran, Shanni N. Silberberg, Susan Lindtner, Kartik Pattabiraman, Alexander Nord, Axel Visel
Publikováno v:
Neuron. 92:59-74
Elucidating the transcriptional circuitry controlling forebrain development requires an understanding of enhancer activity and regulation. We generated stable transgenic mouse lines that express CreERT2 and GFP from ten different enhancer elements wi
Autor:
Jolana Tureckova, Ophir D. Klein, Jan Prochazka, Wen Du, Tomomi Shimogori, Frantisek Spoutil, Renée V. Hoch, Michaela Prochazkova, Radislav Sedlacek, John L.R. Rubenstein, Torsten Wittmann
Publikováno v:
Developmental cell, vol 35, iss 6
SummaryThe proper positioning of organs during development is essential, yet little is known about the regulation of this process in mammals. Using murine tooth development as a model, we have found that cell migration plays a central role in positio
Autor:
John L.R. Rubenstein, Luis Puelles, Leila Taher, Axel Visel, Kartik Pattabiraman, Shanni N. Silberberg, Alexander Nord, Bin Chen, Dongji Zhang, Len A. Pennacchio, Susan Lindtner, Hong Kui Zeng, Olga Golonzhka, Renée V. Hoch
Publikováno v:
Neuron, vol 82, iss 5
Elucidating the genetic control of cerebral cortical (pallial) development is essential for understanding function, evolution, and disorders of the brain. Transcription factors (TFs) that embryonically regulate pallial regionalization are expressed i
Autor:
Ingrid Plajzer-Frick, Sengthavy Phouanenavong, Len A. Pennacchio, Hani Z. Girgis, Gabriel L. McKinsey, Ivan Ovcharenko, Olga Golonzhka, John L.R. Rubenstein, Tommy Kaplan, Renée V. Hoch, Amy Holt, Roya Hosseini, Arnold R. Kriegstein, Shanni N. Silberberg, Leila Taher, Jennifer A. Akiyama, David V. Hansen, Malak Shoukry, Alexander Nord, Edward M. Rubin, Dalit May, Veena Afzal, Matthew J. Blow, Axel Visel, Kartik Pattabiraman
Publikováno v:
Cell, vol 152, iss 4
SummaryThe mammalian telencephalon plays critical roles in cognition, motor function, and emotion. Though many of the genes required for its development have been identified, the distant-acting regulatory sequences orchestrating their in vivo express
Autor:
Nyoman D. Kurniawan, Kerstin Pannek, Renée V. Hoch, Linda J. Richards, Randal X. Moldrich, John L.R. Rubenstein
Publikováno v:
NeuroImage. 51:1027-1036
Diffusion magnetic resonance imaging (dMRI) tractography can be employed to simultaneously analyze three-dimensional white matter tracts in the brain. Numerous methods have been proposed to model diffusion-weighted magnetic resonance data for tractog
Publikováno v:
Seminars in Cell & Developmental Biology. 20:378-386
Embryonic development of the mammalian forebrain is guided by signals from four patterning centers. The concerted actions of these signals transform the anterior neural plate and prosencephalon into discrete forebrain structures including the telence
Publikováno v:
Genesdevelopment. 29(17)
Fibroblast growth factor (Fgf) signaling governs multiple processes important in development and disease. Many lines of evidence have implicated Erk1/2 signaling induced through Frs2 as the predominant effector pathway downstream from Fgf receptors (
Autor:
John L.R. Rubenstein, Tosha Patel, Anthony T. Lee, Vikaas S. Sohal, Kathleen K. A. Cho, Renée V. Hoch
Publikováno v:
Neuron, vol 85, iss 6
SummaryAbnormalities in GABAergic interneurons, particularly fast-spiking interneurons (FSINs) that generate gamma (γ; ∼30–120 Hz) oscillations, are hypothesized to disrupt prefrontal cortex (PFC)-dependent cognition in schizophrenia. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd17fc8eb9de2079ac3b3ef922bfe2d6
https://escholarship.org/uc/item/3rp9c30c
https://escholarship.org/uc/item/3rp9c30c
Autor:
Renée V. Hoch, Philippe Soriano
Highly conserved cell-cell signaling pathways are used reiteratively during development to instruct cellular proliferation, survival, migration, patterning, and differentiation. Responses to cell-cell signaling are dependent on spatial and temporal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdfb0c1468024bb6491c3862fa3511cb
https://doi.org/10.1016/b978-0-12-405945-0.00001-6
https://doi.org/10.1016/b978-0-12-405945-0.00001-6