Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Renée Lengagne"'
1
Akademický článek
Inflammation drives nitric oxide synthase 2 expression by γδ T cells and affects the balance between melanoma and vitiligo associated melanoma
Autor: Laetitia Douguet, Lloyd Bod, Laura Labarthe, Renée Lengagne, Masashi Kato, Isabelle Couillin, Armelle Prévost-Blondel
Publikováno v: OncoImmunology, Vol 7, Iss 9 (2018)
The high expression of inducible nitric oxide synthase (NOS2) by myeloid-derived suppressor cells (MDSCs) is a key mechanism of immune evasion in cancer. Recently we reported that NOS2 is also expressed by γδ T cells in melanoma, contributing to th
Externí odkaz: https://doaj.org/article/cb3790ebbffc4e4c9677965e5fc8fe92
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2
Akademický článek
IL4-induced gene 1 promotes tumor growth by shaping the immune microenvironment in melanoma
Autor: Lloyd Bod, Renée Lengagne, Ludovic Wrobel, Jan Philipp Ramspott, Masashi Kato, Marie-Françoise Avril, Flavia Castellano, Valérie Molinier-Frenkel, Armelle Prévost-Blondel
Publikováno v: OncoImmunology, Vol 6, Iss 3 (2017)
Amino acid catabolizing enzymes emerged as a crucial mechanism used by tumors to dampen immune responses. The L-phenylalanine oxidase IL-4 induced gene 1 (IL4I1) is expressed by tumor-associated myeloid cells of most solid tumors, including melanoma.
Externí odkaz: https://doaj.org/article/182f3bb7dc35400f9e11f88f85e31dd6
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3
Akademický článek
Nitric Oxide Synthase 2 Improves Proliferation and Glycolysis of Peripheral γδ T Cells.
Autor: Laetitia Douguet, Julien Cherfils-Vicini, Lloyd Bod, Renée Lengagne, Eric Gilson, Armelle Prévost-Blondel
Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0165639 (2016)
γδ T cells play critical roles in host defense against infections and cancer. Although advances have been made in identifying γδ TCR ligands, it remains essential to understand molecular mechanisms responsible for in vivo expansion of γδ T cell
Externí odkaz: https://doaj.org/article/9d611c208c724adaaa600abf96c89e28
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4
Akademický článek
T cells contribute to tumor progression by favoring pro-tumoral properties of intra-tumoral myeloid cells in a mouse model for spontaneous melanoma.
Autor: Renée Lengagne, Arnaud Pommier, Jonathan Caron, Laetitia Douguet, Marylène Garcette, Masashi Kato, Marie-Françoise Avril, Jean-Pierre Abastado, Nadège Bercovici, Bruno Lucas, Armelle Prévost-Blondel
Publikováno v: PLoS ONE, Vol 6, Iss 5, p e20235 (2011)
Tumors affect myelopoeisis and induce the expansion of myeloid cells with immunosuppressive activity. In the MT/ret model of spontaneous metastatic melanoma, myeloid cells are the most abundant tumor infiltrating hematopoietic population and their pr
Externí odkaz: https://doaj.org/article/5947da57a7cc4083b7d438b44370afb8
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5
Inflammation drives nitric oxide synthase 2 expression by γδ T cells and affects the balance between melanoma and vitiligo associated melanoma
Autor: Renée Lengagne, Laetitia Douguet, Laura Labarthe, Armelle Prévost-Blondel, Isabelle Couillin, Lloyd Bod, Masashi Kato
Publikováno v: OncoImmunology, Vol 7, Iss 9 (2018)
OncoImmunology
OncoImmunology, Taylor & Francis, 2018, 7 (9), pp.e1484979. ⟨10.1080/2162402X.2018.1484979⟩
The high expression of inducible nitric oxide synthase (NOS2) by myeloid-derived suppressor cells (MDSCs) is a key mechanism of immune evasion in cancer. Recently we reported that NOS2 is also expressed by γδ T cells in melanoma, contributing to th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4924716aeb9df3938a05779f4f5d6451
https://doaj.org/article/cb3790ebbffc4e4c9677965e5fc8fe92
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6
IL-4–Induced Gene 1: A Negative Immune Checkpoint Controlling B Cell Differentiation and Activation
Autor: Armelle Prévost-Blondel, Elena Rondeau, Renée Lengagne, Fériel Bekkat, Yolande Richard, Valérie Molinier-Frenkel, Laetitia Douguet, Flavia Castellano, Cédric Auffray, Lloyd Bod
Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2018, 200 (3), pp.1027-1038. ⟨10.4049/jimmunol.1601609⟩
Journal of Immunology, 2018, 200 (3), pp.1027-1038. ⟨10.4049/jimmunol.1601609⟩
Emerging data highlight the crucial role of enzymes involved in amino acid metabolism in immune cell biology. IL-4–induced gene-1 (IL4I1), a secreted l-phenylalanine oxidase expressed by APCs, has been detected in B cells, yet its immunoregulatory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8565fd58fd162842bafb0e376fd693a9
https://hal.archives-ouvertes.fr/hal-02346124
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7
Inflammatory monocytes are potent antitumor effectors controlled by regulatory CD4 + T cells
Autor: Aurélie Durand, Arnaud Delpoux, Cédric Auffray, Bruno Lucas, Renée Lengagne, Alexandra Audemard, Bruno Martin, Armelle Le Campion, Armelle Prévost-Blondel, Arnaud Pommier, Masashi Kato, Marie-Françoise Avril, Laetitia Douguet
Publikováno v: Proceedings of the National Academy of Sciences. 110:13085-13090
The present study evaluates the impact of immune cell populations on metastatic development in a model of spontaneous melanoma [mice expressing the human RET oncogene under the control of the metallothionein promoter (MT/ret mice)]. In this model, ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3d979e2647e2195eab12ac55ff32ba
https://doi.org/10.1073/pnas.1300314110
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8
Propranolol induces a favourable shift of anti-tumor immunity in a murine spontaneous model of melanoma
Autor: Ludovic Jean Wrobel, Armelle Prévost-Blondel, Renée Lengagne, Lloyd Bod, Masashi Kato, Frédérique-Anne Le Gal
Publikováno v: Oncotarget, Vol. 7, No 47 (2016) pp. 77825-77837
Oncotarget
Oncotarget, Impact journals, 2016, ahead of print. 〈10.18632/oncotarget.12833〉
Oncotarget, Impact journals, 2016, ahead of print. ⟨10.18632/oncotarget.12833⟩
Oncotarget, 2016, ahead of print. ⟨10.18632/oncotarget.12833⟩
International audience; In a previous study on a xenograft model of melanoma, we showed that the beta-adrenergic receptor antagonist propranolol inhibits melanoma development by modulating angiogenesis, proliferation and cell survival. Stress hormone
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cd32ce040168fa7e50e914ef62eb80
https://archive-ouverte.unige.ch/unige:98675
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9
Nitric Oxide Synthase 2 Improves Proliferation and Glycolysis of Peripheral γδ T Cells
Autor: Renée Lengagne, Eric Gilson, Julien Cherfils-Vicini, Laetitia Douguet, Lloyd Bod, Armelle Prévost-Blondel
Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0165639 (2016)
PLoS ONE
γδ T cells play critical roles in host defense against infections and cancer. Although advances have been made in identifying γδ TCR ligands, it remains essential to understand molecular mechanisms responsible for in vivo expansion of γδ T cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8413e08a963c7838dcd8976502773646
http://europepmc.org/articles/PMC5094591?pdf=render
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10
Distinct Role for CD8 T Cells toward Cutaneous Tumors and Visceral Metastases
Autor: Jean-Pierre Abastado, Stéphanie Graff-Dubois, Marylène Garcette, Armelle Prévost-Blondel, Victor H. Engelhard, Masashi Kato, Laurent Rénia, M.-F. Avril, Jean-Gérard Guillet, Renée Lengagne
Publikováno v: The Journal of Immunology. 180:130-137
The growth of immunogenic tumors in immunocompetent individuals is one of the oldest conundrums in tumor immunology. Although the ability of mouse CD8+ T cells to control transplanted tumors is well documented, little is known about their impact on a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0dfc10a60da786a4b4543fb3bbef07
https://doi.org/10.4049/jimmunol.180.1.130
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