Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Renée J. Turner"'
Publikováno v:
Brain Sciences, Vol 13, Iss 11, p 1607 (2023)
Diffuse axonal injury (DAI) is a significant feature of traumatic brain injury (TBI) across all injury severities and is driven by the primary mechanical insult and secondary biochemical injury phases. Axons comprise an outer cell membrane, the axole
Externí odkaz:
https://doaj.org/article/54dbb2b28fca4e4999242dd8f85480d7
Autor:
Annabel J. Sorby-Adams, Oana C. Marian, Isabella M. Bilecki, Levi E. Elms, Jonathan Camargo, Kelly Hall, Robert G. Crowther, Anna V. Leonard, George I. Wadsworth, Joshua H. Spear, Renée J. Turner, Claire F. Jones
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundAssessment of functional impairment following ischaemic stroke is essential to determine outcome and efficacy of intervention in both clinical patients and pre-clinical models. Although paradigms are well described for rodents, comparable m
Externí odkaz:
https://doaj.org/article/dedd7202f21d487091ff4b05d6b80518
Autor:
Frances Corrigan, Ibolja Cernak, Kelly McAteer, Sarah C. Hellewell, Jeffrey V. Rosenfeld, Renée J. Turner, Robert Vink
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Exposure to repeated concussive traumatic brain injury (TBI) and to blast-induced TBI has been associated with the potential development of the neurodegenerative condition known as chronic traumatic encephalopathy (CTE). CTE is characterized
Externí odkaz:
https://doaj.org/article/17f3b7d7e2ed4471a869681cf7a6ab27
Autor:
Annabel J. Sorby-Adams, Anna V. Leonard, Jan W. Hoving, Nawaf Yassi, Robert Vink, Adam J. Wells, Renée J. Turner
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Background and Purpose: The morbidity and early mortality associated with stroke is largely attributable to cerebral edema and elevated intracranial pressure (ICP). Existing pharmacotherapies do not target the underlying pathophysiology and are often
Externí odkaz:
https://doaj.org/article/bae3817f243947d087b039ec057722bf
Autor:
Annabel J. Sorby-Adams, Anna V. Leonard, Levi E. Elms, Oana C. Marian, Jan W. Hoving, Nawaf Yassi, Robert Vink, Emma Thornton, Renée J. Turner
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Background and PurposeCerebral edema and elevated intracranial pressure (ICP) are the leading cause of death in the first week following stroke. Despite this, current treatments are limited and fail to address the underlying mechanisms of swelling, h
Externí odkaz:
https://doaj.org/article/472c8e5aa15c45c6abf8b3c33a54bb11
Autor:
Robert Vink, Renée J. Turner
Publikováno v:
Brain Sciences, Vol 3, Iss 1, Pp 123-142 (2013)
Stroke is a leading cause of death, disability and dementia worldwide. Despite extensive pre-clinical investigation, few therapeutic treatment options are available to patients, meaning that death, severe disability and the requirement for long-term
Externí odkaz:
https://doaj.org/article/5dd701ab10084b9bb815da5be00a364d
Autor:
Rebecca J. Hood, Sonia Sanchez-Bezanilla, Daniel J. Beard, Ruslan Rust, Renée J. Turner, Shannon M. Stuckey, Lyndsey E. Collins-Praino, Frederick R. Walker, Michael Nilsson, Lin Kooi Ong
We have previously demonstrated that a cortical stroke causes persistent impairment of hippocampal-dependent cognitive tasks concomitant with secondary neurodegenerative processes such as amyloid-β accumulation in the hippocampus, a region remote fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48e8f9e9633bb0d1ec9f4d4c9fc53dd
https://doi.org/10.1101/2023.04.24.538047
https://doi.org/10.1101/2023.04.24.538047
Autor:
Ingo Schiessl, Anna V. Leonard, Stuart M. Allan, Philip M.W. Bath, Tracy D. Farr, Renée J. Turner, Annastazia E. Learoyd, Annabel J Sorby-Adams, Fiona Burrows, Rebecca C. Trueman
Publikováno v:
Sorby-Adams, A J, Learoyd, A E, Bath, P M, Burrows, F, Farr, T D, Leonard, A V, Schiessl, I, Allan, S M, Turner, R J & Trueman, R C 2021, ' Glyceryl trinitrate for the treatment of ischaemic stroke: Determining efficacy in rodent and ovine species for enhanced clinical translation ', Journal of Cerebral Blood Flow & Metabolism . https://doi.org/10.1177/0271678X211018901
Journal of Cerebral Blood Flow & Metabolism
Journal of Cerebral Blood Flow & Metabolism
Hypertension is a leading risk factor for death and dependency after ischaemic stroke. However, administering anti-hypertensive medications post-stroke remains contentious with concerns regarding deleterious effects on cerebral blood flow and infarct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f03f6fcfd3df6701ad442d14e5621f5
https://doi.org/10.1177/0271678x211018901
https://doi.org/10.1177/0271678x211018901
Autor:
Rebecca J. Hood, Sonia Sanchez-Bezanilla, Lyndsey E. Collins-Praino, Michael Nilsson, Frederick R. Walker, Renée J. Turner, Lin Kooi Ong
Publikováno v:
J Cereb Blood Flow Metab
There is emerging evidence suggesting that a cortical stroke can cause delayed and remote hippocampal dysregulation, leading to cognitive impairment. In this study, we aimed to investigate motor and cognitive outcomes after experimental stroke, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1546e32f2e0a90315ab73e1027ab7cc
https://doi.org/10.1177/0271678x211005877
https://doi.org/10.1177/0271678x211005877
Publikováno v:
Medical Devices: Evidence and Research. 12:479-487
Introduction Evidence suggests treatments guided by brain oxygen levels improve patient outcomes following severe traumatic brain injury; however, brain oxygen levels are not routinely monitored as an effective non-invasive method has not been establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3dbb0f422af64e6e0330cc743c531af
https://doi.org/10.2147/mder.s235804
https://doi.org/10.2147/mder.s235804