Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Renée H. Martin"'
Autor:
Renée H. Martin, Helen G. Tempest
Publikováno v:
Current Opinion in Obstetrics & Gynecology. 21:223-227
Purpose of review Infertility is a growing problem that affects a surprisingly high number of couples (15%) of which the causes often remain 'unexplained'. However, more and more genetic causes underlying male infertility are emerging. Recent finding
Publikováno v:
Fertility and Sterility. 91:185-192
Objective To investigate whether there are intra-individual and/or inter-individual variations in sperm aneuploidy frequencies within the normal male population, and, if this is the case, whether they are sporadic or time-stable variants. Design Pros
Autor:
E. Ko, Alfred Rademaker, Renée H. Martin, Maria Oliver-Bonet, F. Sun, Paul J. Turek, M. Mikhaail-Philips
Publikováno v:
Molecular Human Reproduction
Both aberrant meiotic recombination and an increased frequency of sperm aneuploidy have been observed in infertile men. However, this association has not been demonstrated within individual men. The purpose of this study was to determine the associat
Autor:
Thomas Liehr, Fei Sun, Jie Lian, Paul J. Turek, Maria Oliver-Bonet, Yimeng Yin, Renée H. Martin, E. Ko
Publikováno v:
Universitat Autònoma de Barcelona
Crossovers (COs) generated by homologous recombination ensure the proper segregation of chromosomes during meiosis. COs exhibit interference, which leads to widely spaced COs along chromosomes. Strong positive CO interference has been found in humans
Autor:
Renée H. Martin
Publikováno v:
Reproductive BioMedicine Online. 16:523-531
Chromosome anomalies are extraordinarily common in human gametes, with approximately 21% of oocytes and 9% of spermatozoa abnormal. The types of abnormalities are quite different since most abnormal oocytes are aneuploid, whereas the majority of abno
Autor:
Arthur Leader, Sandra Dill, Calvin Greene, Sherry Dale, François Bissonnette, Michael Marrin, Beverly Hanck, Edward G. Hughes, Renée H. Martin, Mathias Gysler, Sharon T. Mortimer, Benjamin Tsang, Dean A. Van Vugt, Sarah D. McDonald, Lisa Cowan, Jean Cohen, A. Albert Yuzpe, Jocelyn Smith, Jason K. Min, John A. Collins, David Mortimer
Publikováno v:
Reproductive BioMedicine Online. 14:773-790
This paper reports the proceedings of a consensus meeting on the incidence and complications of multiple gestation in Canada. In addition to background presentations about current and possible future practice in Canada, the expert panel also develope
Publikováno v:
Archives of Andrology. 53:157-160
Griseofulvin is known to interfere with chromosome segregation by binding to microtubule-associated proteins. Studies in mouse germ cells have demonstrated that griseofulvin can induce aneuploidy (numerical chromosome abnormalities) at therapeutic co
Autor:
Thomas Liehr, Heike Starke, Alfred Rademaker, E. Ko, F. Sun, Renée H. Martin, Maria Oliver-Bonet
Publikováno v:
Cytogenetic and Genome Research. 119:27-32
During meiosis, homologous chromosome pairing and synapsis are essential for subsequent meiotic recombination (crossing-over). Discontinuous regions (gaps) and unsynapsed regions (splits) were most frequently observed in the heterochromatic regions o
Autor:
Renée H. Martin
Publikováno v:
Reproductive Toxicology. 22:142-147
The last few years have witnessed an explosion in the information about chromosome abnormalities in human sperm and the meiotic events that predispose to these abnormalities. We have determined that all chromosomes are susceptible to nondisjunction,
Autor:
Heike Starke, Paul J. Turek, Maria Oliver-Bonet, Renée H. Martin, Alfred Rademaker, Evelyn Ko, Thomas Liehr, F. Sun
Publikováno v:
Human Molecular Genetics. 15:2376-2391
Meiotic recombination is essential for the segregation of homologous chromosomes and the formation ofnormal haploid gametes. Little is known about patterns of meiotic recombination in human germ cells orthe mechanisms that control these patterns. Doc