Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Renée Dutton"'
Publikováno v:
The Journal of Neuroscience. 19:2601-2608
Sonic hedgehog (Shh) is strongly implicated in the development of ventral structures in the nervous system. Addition of Sonic hedgehog protein to chick spinal cord explants induces floor plate and motoneuron development. Whether Shh acts directly to
Publikováno v:
Journal of Investigative Dermatology Symposium Proceedings. 2(1):8-13
This article is concerned with the idea that neural precursor cells in vertebrates can self-renew and give rise to all cell types within the nervous system. Supportive evidence for this notion of neural stem cells comes from clonal analyses undertake
Autor:
Trevor J. Kilpatrick, David P. Gearing, Renée Dutton, Mark Murphy, Perry F. Bartlett, Seong-Seng Tan, Linda J. Richards
Publikováno v:
European Journal of Neuroscience. 8:291-299
Previously we have shown that leukaemia inhibitory factor (LIF) potentiates the development of murine spinal cord neurons in vitro, suggesting that it, or related factors, may play an important regulatory role in neuronal development. We have further
Autor:
Mark W. Murphy, Adam C. Puche, Linda J. Richards, Renée Dutton, Trevor J. Kilpatrick, P. S. Talman, Perry F. Bartlett, Seong-Seng Tan, Brian Key
Publikováno v:
Proceedings of the National Academy of Sciences. 92:10079-10083
We have investigated the differentiation potential of precursor cells within the developing spinal cord of mice and have shown that spinal cord cells from embryonic day 10 specifically give rise to neurons when plated onto an astrocytic monolayer, As
Autor:
Simon A. Koblar, Victor Nurcombe, S. S. Cheema, Renée Dutton, P. S. Talman, Trevor J. Kilpatrick, L. R. Richards, Marilyn Ford, Perry F. Bartlett, V. Likiardopoulos, Mark Murphy, Gordon F. Brooker, Karen Bailey
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 22:559-562
1. Precursors form the neuroepithelium of the developing cortex and also from the adult sub-ventricular zone, can be cloned in vitro after stimulation with fibroblast growth factor (FGF)-2 and have the potential to give rise to both neurons and glia.
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 26:746-748
1. The development of ventral cell types in the spinal cord, including motor neurons, requires the growth factor Sonic hedgehog (Shh). However, it is still unknown whether Shh acts directly on precursors to induce these cell types and whether additio
Autor:
Renée Dutton, Perry F. Bartlett
Publikováno v:
Developmental neuroscience. 22(1-2)
The adult mouse subventricular zone (SVZ) contains precursor cells capable of generating new neurons which populate the olfactory bulb. The SVZ precursors, however, appear to be restricted in their capacity to generate neurons in other regions of the
Autor:
Mark Murphy, Trevor J. Kilpatrick, Clare Faux, Perry F. Bartlett, Ann M. Turnley, Gordon J.f. Brooker, Renée Dutton
Publikováno v:
Immunology and cell biology. 76(5)
In the developing forebrain, mounting evidence suggests that neural stem cell proliferation and differentiation is regulated by growth factors. In vitro in the presence of serum, stem cell proliferation is predominantly mediated by fibroblast growth
Publikováno v:
Journal of neuroimmunology. 78(1-2)
Class I MHC protein is induced in glia but not mature neurons by IFN- γ . We have compared IFN- γ signal transduction in these populations. There were identical levels of STAT1 homodimers and IRF-1 by gel-shift and IRF-1 mRNA was induced equally. H
Publikováno v:
Progress in neurobiology. 52(5)
A number of different cytokines, each initially characterized on the basis of very different biological activities, all have very similar signalling pathways and share a similar tertiary structure. These cytokines include leukaemia inhibitory factor,