Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Renée C. LeBoeuf"'
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 12, Pp 2337-2347 (2015)
In addition to triacylglycerols, adipocytes contain a large reserve of unesterified cholesterol. During adipocyte lipolysis and cell death seen during severe obesity and weight loss, free fatty acids and cholesterol become available for uptake and pr
Externí odkaz:
https://doaj.org/article/3831ec15ee7b48a98cecdb2f21a09d9d
Autor:
Matthew L. Brown, Katsumasa Yui, Jonathan D. Smith, Renée C. LeBoeuf, Wei Weng, Patrick K. Umeda, Ran Li, Ruiling Song, Sandra H. Gianturco, William A. Bradley
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 8, Pp 1181-1191 (2002)
Previously we cloned the human macrophage apolipoprotein B-48 receptor (ApoB-48R) and documented its expression in human atherosclerotic foam cells (1). Now we have identified and characterized the murine macrophage apob-48r cDNA gene sequence and it
Externí odkaz:
https://doaj.org/article/d264069dc3694ec2b31db995a43c7f46
Publikováno v:
Neuroreport. 14(1)
Increasing evidence suggests that intraneuronal amyloid-beta (Abeta) accumulation may be an early event in Alzheimer's disease (AD) pathogenesis. However direct in vivo evidence regarding initial Abeta seeding is missing. Using an APP transgenic mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c18050fbea1e1fb137f335fd23606e0
https://pubmed.ncbi.nlm.nih.gov/12544843
https://pubmed.ncbi.nlm.nih.gov/12544843
Autor:
Matthew L, Brown, Katsumasa, Yui, Jonathan D, Smith, Renée C, LeBoeuf, Wei, Weng, Patrick K, Umeda, Ran, Li, Ruiling, Song, Sandra H, Gianturco, William A, Bradley
Publikováno v:
Journal of lipid research. 43(8)
Previously we cloned the human macrophage apolipoprotein B-48 receptor (ApoB-48R) and documented its expression in human atherosclerotic foam cells (1). Now we have identified and characterized the murine macrophage apob-48r cDNA gene sequence and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37481b2160a9466d8ab8a37c67fcd6df
https://pubmed.ncbi.nlm.nih.gov/12177162
https://pubmed.ncbi.nlm.nih.gov/12177162
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 5, Pp 848-857 (2016)
ABCA1 exports excess cholesterol from cells to apoA-I and is essential for HDL synthesis. Genetic studies have shown that ABCA1 protects against cardiovascular disease. We have previously shown that the interaction of apoA-I with ABCA1 activates sign
Externí odkaz:
https://doaj.org/article/6944cce8a13c4e88a077b4c51e4748af
Autor:
Chongren Tang, Yuhua Liu, Wendy Yang, Carl Storey, Tim S. McMillen, Barbara A. Houston, Jay W. Heinecke, Renee C. LeBoeuf
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 1, Pp 100-108 (2016)
Low-grade chronic inflammation plays an important role in the pathogenesis of obesity-induced insulin resistance. ABCA1 is essential for reverse cholesterol transport and HDL synthesis, and protects against macrophage inflammation. In the present stu
Externí odkaz:
https://doaj.org/article/3c2d4b94edcd440f90cb2a86785846c4
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 7, Pp 1719-1728 (2010)
Accumulation of cholesterol in arterial macrophages may contribute to diabetes-accelerated atherosclerotic cardiovascular disease. The ATP-binding cassette transporter ABCA1 is a cardioprotective membrane protein that mediates cholesterol export from
Externí odkaz:
https://doaj.org/article/6208e2359dda4783a7c0ccc79a081fca
Autor:
Susanne M. Clee, Nagat Bissada, Fudan Miao, Li Miao, A. David Marais, Howard E. Henderson, Pieternel Steures, Janet McManus, Bruce McManus, Renee C. LeBoeuf, John J.P. Kastelein, Michael R. Hayden
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 4, Pp 521-531 (2000)
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism, and has been hypothesized to exert either pro- or anti-atherogenic effects, depending on its localization. Decreased plasma LPL activity is associated with the high triglyceride (TG)
Externí odkaz:
https://doaj.org/article/a365ed31b6cf4f43864defa640172edd