Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Renée A, Douma"'
Autor:
Tom D. Y. Reijnders, Alex R. Schuurman, Jan Verhoeff, Marlous van den Braber, Renée A. Douma, Daniël R. Faber, Alberta G. A. Paul, W. Joost Wiersinga, Anno Saris, Juan J. Garcia Vallejo, Tom van der Poll
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCommunity-acquired pneumonia (CAP) represents a major health burden worldwide. Dysregulation of the immune response plays an important role in adverse outcomes in patients with CAP.MethodsWe analyzed peripheral blood mononuclear cells by 36
Externí odkaz:
https://doaj.org/article/1c395277784f45d4a2292698566e39b7
Autor:
Justin de Brabander, Erik H. A. Michels, Christine C. A. van Linge, Osoul Chouchane, Renée A. Douma, Tom D. Y. Reijnders, Alex R. Schuurman, Tjitske S. R. van Engelen, Amsterdam UMC COVID-19 biobank study group, W. Joost Wiersinga, Tom van der Poll
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Dexamethasone improves clinical outcomes in COVID-19 patients requiring supplementary oxygen. We investigated possible mechanisms of action by comparing sixteen plasma host response biomarkers in general ward patients before and after implem
Externí odkaz:
https://doaj.org/article/154585d74b9c4aa5b3cd44c9f52dad8a
Autor:
Alex R. Schuurman, Tom D.Y. Reijnders, Tjitske S.R. van Engelen, Valentine Léopold, Justin de Brabander, Christine van Linge, Michiel Schinkel, Liza Pereverzeva, Bastiaan W. Haak, Xanthe Brands, Maadrika M.N.P. Kanglie, Inge A.H. van den Berk, Renée A. Douma, Daniël R. Faber, Prabath W.B. Nanayakkara, Jaap Stoker, Jan M. Prins, Brendon P. Scicluna, W. Joost Wiersinga, Tom van der Poll
Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104082- (2022)
Summary: Background: Community-acquired pneumonia (CAP) can be caused by a variety of pathogens, of which Streptococcus pneumoniae, Influenza and currently SARS-CoV-2 are the most common. We sought to identify shared and pathogen-specific host respon
Externí odkaz:
https://doaj.org/article/85d23ff382c448b9ae4d9aa108476b90
Autor:
Jamie van Son, Sabrina M. Oussaada, Aydin Şekercan, Martijn Beudel, Dave A. Dongelmans, Sander van Assen, Ingo A. Eland, Hazra S. Moeniralam, Tom P. J. Dormans, Colin A. J. van Kalkeren, Renée A. Douma, Daisy Rusch, Suat Simsek, Limmie Liu, Ruud S. Kootte, Caroline E. Wyers, Richard G. IJzerman, Joop P. van den Bergh, Coen D. A. Stehouwer, Max Nieuwdorp, Kasper W. ter Horst, Mireille J. Serlie
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
ObjectiveTo evaluate the association between overweight and obesity on the clinical course and outcomes in patients hospitalized with COVID-19.DesignRetrospective, observational cohort study.MethodsWe performed a multicenter, retrospective, observati
Externí odkaz:
https://doaj.org/article/923713b42dae4d21a0c02560c6c207a4
Autor:
Alex R. Schuurman, Valentine Léopold, Liza Pereverzeva, Osoul Chouchane, Tom D. Y. Reijnders, Justin de Brabander, Renée A. Douma, Michel van Weeghel, Eric Wever, Bauke V. Schomaker, Frédéric M. Vaz, Willem Joost Wiersinga, Cornelis van't Veer, Tom van der Poll
Publikováno v:
Thrombosis and haemostasis, 122(10), 1683-1692. Schattauer GmbH
Background Activated platelets have been implicated in the proinflammatory and prothrombotic phenotype of coronavirus disease 2019 (COVID-19). While it is increasingly recognized that lipids have important structural and signaling roles in platelets,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773f246c6e3f5883ebcda2625cdd4a4d
https://pure.amc.nl/en/publications/the-platelet-lipidome-is-altered-in-patients-with-covid19-and-correlates-with-platelet-reactivity(b81f323f-b32d-4845-9b8d-1b16edf32478).html
https://pure.amc.nl/en/publications/the-platelet-lipidome-is-altered-in-patients-with-covid19-and-correlates-with-platelet-reactivity(b81f323f-b32d-4845-9b8d-1b16edf32478).html
Autor:
Christine van Linge, Cornelis van 't Veer, Osoul Chouchane, Rienk Nieuwland, W. Joost Wiersinga, Anno Saris, Liza Pereverzeva, Renée A. Douma, Tom D Y Reijnders, Tom van der Poll, Valentine Léopold, Alex R. Schuurman, Justin de Brabander
Publikováno v:
Thrombosis and haemostasis, 121(9), 1258-1262. Schattauer GmbH
Léopold, V, Pereverzeva, L, Schuurman, A R, Reijnders, T D Y, Saris, A, de Brabander, J, van Linge, C C A, Douma, R A, Chouchane, O, Nieuwland, R, Wiersinga, W J, van't Veer, C & van der Poll, T 2021, ' Platelets are hyperactivated but show reduced glycoprotein VI reactivity in COVID-19 patients ', Thrombosis and Haemostasis, vol. 121, no. 9, pp. 1258-1262 . https://doi.org/10.1055/a-1347-5555
Thrombosis and Haemostasis
Thrombosis and Haemostasis, 121(9), 1258-1262. Schattauer GmbH
Léopold, V, Pereverzeva, L, Schuurman, A R, Reijnders, T D Y, Saris, A, de Brabander, J, van Linge, C C A, Douma, R A, Chouchane, O, Nieuwland, R, Wiersinga, W J, van't Veer, C & van der Poll, T 2021, ' Platelets are hyperactivated but show reduced glycoprotein VI reactivity in COVID-19 patients ', Thrombosis and Haemostasis, vol. 121, no. 9, pp. 1258-1262 . https://doi.org/10.1055/a-1347-5555
Thrombosis and Haemostasis
Thrombosis and Haemostasis, 121(9), 1258-1262. Schattauer GmbH
Autor:
Niels C. Gritters van den Oever, Tom Dormans, Mark M. Smits, Auke C Reidinga, Trynke Hoekstra, Suat Simsek, Joop P. W. van den Bergh, Rick I. Meijer, Hazra S. Moeniralam, Renée A. Douma
Publikováno v:
Amsterdam UMC COVID-19 biobank study group 2021, ' Treatment with a DPP-4 inhibitor at time of hospital admission for COVID-19 is not associated with improved clinical outcomes: data from the COVID-PREDICT cohort study in The Netherlands ', Journal of Diabetes and Metabolic Disorders, vol. 20, no. 2, pp. 1155-1160 . https://doi.org/10.1007/s40200-021-00833-z
Journal of Diabetes and Metabolic Disorders, 20(2), 1155-1160. BioMed Central Ltd.
Amsterdam UMC COVID-19 biobank study group 2021, ' Treatment with a DPP-4 inhibitor at time of hospital admission for COVID-19 is not associated with improved clinical outcomes : data from the COVID-PREDICT cohort study in The Netherlands ', Journal of diabetes and metabolic disorders, vol. 20, no. 2, pp. 1155-1160 . https://doi.org/10.1007/s40200-021-00833-z
Journal of diabetes and metabolic disorders, 20(2), 1155-1160. BioMed Central Ltd.
Journal of Diabetes and Metabolic Disorders
Journal of Diabetes and Metabolic Disorders, 20(2), 1155-1160. BioMed Central Ltd.
Amsterdam UMC COVID-19 biobank study group 2021, ' Treatment with a DPP-4 inhibitor at time of hospital admission for COVID-19 is not associated with improved clinical outcomes : data from the COVID-PREDICT cohort study in The Netherlands ', Journal of diabetes and metabolic disorders, vol. 20, no. 2, pp. 1155-1160 . https://doi.org/10.1007/s40200-021-00833-z
Journal of diabetes and metabolic disorders, 20(2), 1155-1160. BioMed Central Ltd.
Journal of Diabetes and Metabolic Disorders
Purpose Inhibition of dipeptidyl peptidase (DPP-)4 could reduce coronavirus disease 2019 (COVID-19) severity by reducing inflammation and enhancing tissue repair beyond glucose lowering. We aimed to assess this in a prospective cohort study. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27aa6e87dd7907382c9a11fb3d5a0466
https://research.vumc.nl/en/publications/d4c70d35-7142-4ecb-9b6e-506ac5907956
https://research.vumc.nl/en/publications/d4c70d35-7142-4ecb-9b6e-506ac5907956
Autor:
Justin, de Brabander, Erik H A, Michels, Christine C A, van Linge, Osoul, Chouchane, Renée A, Douma, Tom D Y, Reijnders, Alex R, Schuurman, Tjitske S R, van Engelen, W Joost, Wiersinga, Diederik, van de Beek
Publikováno v:
Amsterdam UMC COVID-19 biobank study group 2022, ' Association between dexamethasone treatment and the host response in COVID-19 patients admitted to the general ward ', Respiratory Research, vol. 23, no. 1, pp. 145 . https://doi.org/10.1186/s12931-022-02060-3
Respiratory research, 23(1). BioMed Central
Respiratory Research, 23(1)
Respiratory research, 23(1). BioMed Central
Respiratory Research, 23(1)
Dexamethasone improves clinical outcomes in COVID-19 patients requiring supplementary oxygen. We investigated possible mechanisms of action by comparing sixteen plasma host response biomarkers in general ward patients before and after implementation
Autor:
Auke C Reidinga, Suat Simsek, Frits H.M. van Osch, Harry R. Büller, Nicole P. Juffermans, Saskia Middeldorp, Niels Gritters, Didier Collard, Matthijs Oudkerk, Marjolein A Heuvelmans, Hugo ten Cate, Renée A. Douma, Eline A Vlot, Thijs F. van Haaps, Nick van Es, Alexander P.J. Vlaar, Arno Maas, Marije ten Wolde, Michiel Coppens, Martijn Beudel, Martijn D. de Kruif, Joop P. W. van den Bergh
Publikováno v:
Thrombosis Research
The New England Journal of Medicine
Thrombosis Research, 208, 35-38
Thrombosis research, 208, 35-38. Elsevier Limited
Thrombosis Research, 208, 35-38. Elsevier Science
Thrombosis Research, 208, pp. 35-38
The New England Journal of Medicine
Thrombosis Research, 208, 35-38
Thrombosis research, 208, 35-38. Elsevier Limited
Thrombosis Research, 208, 35-38. Elsevier Science
Thrombosis Research, 208, pp. 35-38
Background Thrombosis and inflammation may contribute to morbidity and mortality among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation would improve outcomes in critically ill patients with Cov
Autor:
Marcel J. H. Aries, Auke C Reidinga, Lucas A. Ramos, Kim C. E. Sigaloff, Wouter V. Potters, Suat Simsek, Iwan C. C. van der Horst, Peter G. Noordzij, Tom Dormans, Caroline E. Wyers, Henk A. Marquering, Maarten C. Ottenhoff, Ella H C van den Hout, Michiel Schinkel, Dan Piña-Fuentes, Guido van Wingen, Deborah Hubers, Lianne de Haan, Roger J M W Rennenberg, Rajat M. Thomas, Daisy Rusch, W. Joost Wiersinga, Christian Herff, Marcus L.F. Janssen, Shi Hu, Renée A. Douma, Niels C. Gritters van den Oever, Egill Axfjord Fridgeirsson, Martijn D. de Kruif, Max Welling, Joop P. W. van den Bergh, Martijn Beudel, Paul W. G. Elbers, Pieter L. Kubben, Lucas M Fleuren, David T B Buis
Publikováno v:
BMJ Open, 11(7):e047347. BMJ Publishing Group
Ottenhoff, M C, Ramos, L A, Potters, W, Janssen, M L F, Hubers, D, Hu, S, Fridgeirsson, E A, Pina-Fuentes, D, Thomas, R, van der Horst, I C C, Herff, C, Kubben, P, Elbers, P W G, Marquering, H A, Welling, M, Simsek, S, de Kruif, M D, Dormans, T, Fleuren, L M, Schinkel, M, Noordzij, P G, van den Bergh, J P, Wyers, C E, Buis, D T B, Wiersinga, W J, van den Hout, E H C, Reidinga, A C, Rusch, D, Sigaloff, K C E, Douma, R A, de Haan, L, van den Oever, N C G, Rennenberg, R J M W, van Wingen, G A, Aries, M J H & Beudel, M 2021, ' Predicting mortality of individual patients with COVID-19: A multicentre Dutch cohort ', BMJ Open, vol. 11, no. 7, e047347 . https://doi.org/10.1136/bmjopen-2020-047347, https://doi.org/10.1136/bmjopen-2020-047347
BMJ Open
BMJ Open, Vol 11, Iss 7 (2021)
BMJ open, 11(7):e047347. BMJ Publishing Group
Ottenhoff, M C, Ramos, L A, Potters, W, Janssen, M L F, Hubers, D, Hu, S, Fridgeirsson, E A, Pina-Fuentes, D, Thomas, R, van der Horst, I C C, Herff, C, Kubben, P, Elbers, P W G, Marquering, H A, Welling, M, Simsek, S, de Kruif, M D, Dormans, T, Fleuren, L M, Schinkel, M, Noordzij, P G, van den Bergh, J P, Wyers, C E, Buis, D T B, Wiersinga, W J, van den Hout, E H C, Reidinga, A C, Rusch, D, Sigaloff, K C E, Douma, R A, de Haan, L, van den Oever, N C G, Rennenberg, R J M W, van Wingen, G A, Aries, M J H & Beudel, M 2021, ' Predicting mortality of individual patients with COVID-19: A multicentre Dutch cohort ', BMJ Open, vol. 11, no. 7, e047347 . https://doi.org/10.1136/bmjopen-2020-047347, https://doi.org/10.1136/bmjopen-2020-047347
BMJ Open
BMJ Open, Vol 11, Iss 7 (2021)
BMJ open, 11(7):e047347. BMJ Publishing Group
ObjectiveDevelop and validate models that predict mortality of patients diagnosed with COVID-19 admitted to the hospital.DesignRetrospective cohort study.SettingA multicentre cohort across 10 Dutch hospitals including patients from 27 February to 8 J