Zobrazeno 1 - 10
of 135
pro vyhledávání: '"René de Gelder"'
Autor:
Alexander B. C. Deutman, Tim Woltinge, Jan M. M. Smits, René De Gelder, Johannes A. A. W. Elemans, Roeland J. M. Nolte, Alan E. Rowan
Publikováno v:
Molecules, Vol 19, Iss 4, Pp 5278-5300 (2014)
The synthesis and switching properties of two “basket handle” porphyrin isomers is described. The cis-oriented meso-phenyl groups of these porphyrins are linked at their ortho-positons via benzocrown-ether-based spacers, which as a result of slow
Externí odkaz:
https://doaj.org/article/11bfbf12f6184a69a29ff096def04846
Autor:
Joop H. ter Horst, Paul Tinnemans, Herman J. M. Kramer, Hugo Meekes, René de Gelder, Weiwei Li, Mariëtte de Groen
Publikováno v:
Crystal Growth & Design, 21, 112-124
Crystal Growth & Design, 21, 1, pp. 112-124
Crystal Growth & Design, 21, 1, pp. 112-124
Cocrystallization of racemic-compound-forming chiral molecules can result in conglomerate cocrystals or diastereomerically related cocrystals, which enable the application of chiral separation techniques such as preferential crystallization and class
Autor:
Maxime D. Charpentier, Jan-Joris Devogelaer, Arnoud Tijink, Hugo Meekes, Paul Tinnemans, Elias Vlieg, René de Gelder, Karen Johnston, Joop H. ter Horst
Publikováno v:
Crystal Growth & Design, 22, 5511-5525
Crystal Growth & Design, 22, 9, pp. 5511-5525
Crystal Growth & Design, 22, 9, pp. 5511-5525
Pharmaceutical cocrystals are highly interesting due to their effect on physicochemical properties and their role in separation technologies, particularly for chiral molecules. Detection of new cocrystals is a challenge, and robust screening methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fbf9d462e6123af4fef6a9dbb4d434
http://hdl.handle.net/2066/283798
http://hdl.handle.net/2066/283798
Autor:
Paul Tinnemans, Maarten Honing, René de Gelder, Wester de Poel, Floris P. J. T. Rutjes, Alexander L. L. Duchateau, Elias Vlieg
Publikováno v:
Chemistry : a European Journal, 25, pp. 14999-15003
Chemistry : a European Journal, 25, 14999-15003
Chemistry: a European journal, 25(65), 14999-15003. Wiley-VCH Verlag
Chemistry : a European Journal, 25, 14999-15003
Chemistry: a European journal, 25(65), 14999-15003. Wiley-VCH Verlag
The crystalline sponge method allows for the elucidation of the (absolute) structure of molecules using single-crystal X-ray diffraction and eliminates the need for crystals of the target compound. An important limitation for the application of the c
Publikováno v:
Acta Crystallographica, Section B-Structural Science, Crystal Engineering and Materials, 75, pp. 371-383
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials
Acta Crystallographica, Section B-Structural Science, Crystal Engineering and Materials, 75, 371-383
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials
Acta Crystallographica, Section B-Structural Science, Crystal Engineering and Materials, 75, 371-383
To obtain a better understanding of which coformers to combine for the successful formation of a cocrystal, techniques from data mining and network science are used to analyze the data contained in the Cambridge Structural Database (CSD). A network o
Autor:
Elias Vlieg, Karen Johnston, Paul Tinnemans, Gérard Coquerel, Valérie Dupray, Hugo Meekes, Joop H. ter Horst, Jan-Joris Devogelaer, Arnoud Tijink, René de Gelder, Maxime D. Charpentier
In this study, co-crystals for Praziquantel (PZQ), an anthelmintic drug used to treat schistosomiasis, are predicted with network-based link prediction. Single crystals of twelve co-crystal indications were grown and subjected to a structural analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd3fe6ba7df4ec07691ddf3350eb6ce
https://doi.org/10.26434/chemrxiv.13562795
https://doi.org/10.26434/chemrxiv.13562795
Publikováno v:
Carbohydrate research. 496
The idopyranose ring plays a pivotal role in the conformational, dynamical, and intermolecular binding aspects of glycosaminoglycans like heparin and dermatan sulfate and it was early on assigned a role in the Sugar Code governing biological recognit
Autor:
Roel A. Kleinnijenhuis, Jan H. van Maarseveen, René de Gelder, Henk Hiemstra, Jan M. M. Smits, Remmelt J. Beuving, Ginger Lutteke
Publikováno v:
European Journal of Organic Chemistry. 2016:5845-5854
An enantioselective synthesis of the right-hand substructure of solanoeclepin A has been developed. The key step was an intramolecular [2+2] photocycloaddition between an allene and a butenolide providing a methylenecyclobutane with three quaternary
Autor:
Sander J. T. Brugman, Paul Tinnemans, Jan-Joris Devogelaer, Elias Vlieg, Hugo Meekes, René de Gelder
Publikováno v:
CrystEngComm, 21, 6875-6885
CrystEngComm
CrystEngComm, 21, 44, pp. 6875-6885
CrystEngComm
CrystEngComm, 21, 44, pp. 6875-6885
Cocrystallization is an attractive formulation tool for tuning the physicochemical properties of a compound while not altering its molecular structure and has gained interest from both industry and academia. Although the design strategy for cocrystal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc732eef6687394329e45d2cb9e55af
http://hdl.handle.net/2066/214377
http://hdl.handle.net/2066/214377
Autor:
Floris P. J. T. Rutjes, Wester de Poel, Maarten Honing, Paul Tinnemans, Elias Vlieg, René de Gelder, Alexander L. L. Duchateau
Publikováno v:
Crystal Growth & Design
Crystal Growth & Design, 18, 126-132
Crystal Growth & Design, 18, 1, pp. 126-132
Crystal Growth & Design, 18, 126-132
Crystal Growth & Design, 18, 1, pp. 126-132
The use of an achiral metal–organic framework for structure determination of chiral compounds is demonstrated for camphene and pinene. The structure of enantiopure β-pinene can be resolved using the crystalline sponge method. However, α-pinene ca