Zobrazeno 1 - 10
of 34
pro vyhledávání: '"René Thierbach"'
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 648 (2024)
Aim: The purpose of this study was to investigate whether a clinical effect of Lactobacillus reuteri in supportive periodontal therapy can already be detected with a minimum dose of one tablet a day and a minimum observation and intake period of 3 mo
Externí odkaz:
https://doaj.org/article/9aa34090e4bf46248171dd6468327933
Autor:
Christian Marx, Jürgen Sonnemann, Oliver D. K. Maddocks, Lisa Marx-Blümel, Mandy Beyer, Doerte Hoelzer, René Thierbach, Claudia Maletzki, Michael Linnebacher, Thorsten Heinzel, Oliver H. Krämer
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background Metabolic adaptations can allow cancer cells to survive DNA-damaging chemotherapy. This unmet clinical challenge is a potential vulnerability of cancer. Accordingly, there is an intense search for mechanisms that modulate cell met
Externí odkaz:
https://doaj.org/article/b54be1c1c57b4247a2dde92cec4134b4
Autor:
Christian Marx, Jürgen Sonnemann, Mandy Beyer, Oliver D. K. Maddocks, Sergio Lilla, Irene Hauzenberger, Andrea Piée‐Staffa, Kanstantsin Siniuk, Suneetha Nunna, Lisa Marx‐Blümel, Martin Westermann, Tobias Wagner, Felix B. Meyer, René Thierbach, Christina S. Mullins, Said Kdimati, Michael Linnebacher, Francesco Neri, Thorsten Heinzel, Zhao‐Qi Wang, Oliver H. Krämer
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3404-3429 (2021)
Late‐stage colorectal cancer (CRC) is still a clinically challenging problem. The activity of the tumor suppressor p53 is regulated via post‐translational modifications (PTMs). While the relevance of p53 C‐terminal acetylation for transcription
Externí odkaz:
https://doaj.org/article/0b74c48fb69942fab1d217753fe500f2
Autor:
Felix B. Meyer, Sophie Goebel, Sonja B. Spangel, Christiane Leovsky, Doerte Hoelzer, René Thierbach
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background Despite considerable medical proceedings, cancer is still a leading cause of death. Major problems for tumor therapy are chemoresistance as well as toxic side effects. In recent years, the additional treatment with the antidiabeti
Externí odkaz:
https://doaj.org/article/e00d01434c89406688fe5d09c52514c4
Autor:
Christian Marx, Marc U. Schaarschmidt, Joanna Kirkpatrick, Lisa Marx-Blümel, Melisa Halilovic, Martin Westermann, Doerte Hoelzer, Felix B. Meyer, Yibo Geng, Katrin Buder, Hauke M. Schadwinkel, Kanstantsin Siniuk, Sabine Becker, René Thierbach, James F. Beck, Jürgen Sonnemann, Zhao-Qi Wang
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Introduction Ewing's sarcoma is an aggressive childhood malignancy whose outcome has not substantially improved over the last two decades. In this study, combination treatments of the HSP90 inhibitor AUY922 with either the ATR inhibitor VE82
Externí odkaz:
https://doaj.org/article/d8fb96d8e11f4e79b641bb5a2f9a1a6f
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1831 (2021)
The BALB/c cell transformation assay (BALB-CTA) considers inter- and intra-tumor heterogeneities and affords the possibility of a direct comparison between untransformed and malignant cells. In the present study, we established monoclonal cell lines
Externí odkaz:
https://doaj.org/article/7c01261219604573a8f6622e3365cb22
Publikováno v:
Biology Open, Vol 5, Iss 5, Pp 654-661 (2016)
Friedreich ataxia is a neurodegenerative disease caused by a GAA triplet repeat expansion in the first intron of the frataxin gene, which results in reduced expression levels of the corresponding protein. Despite numerous animal and cellular models,
Externí odkaz:
https://doaj.org/article/20bacd2e512643318288cc2953ea82d5
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 10, Iss 5, Pp ZC34-ZC38 (2016)
Introduction: Matrix Metalloproteinase (MMP) -8 plays crucial role in pathogenesis of periodontitis and is also a possible biomarker candidate in peri-implantitis. Aim: The aim of the study was to analyse MMP-8 levels in periImplant Sulcus Fluid (
Externí odkaz:
https://doaj.org/article/65de2f11fc114bcd9b9108f5501cf0a0
Autor:
Tim J Schulz, Markus Glaubitz, Doreen Kuhlow, René Thierbach, Marc Birringer, Pablo Steinberg, Andreas F H Pfeiffer, Michael Ristow
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1013 (2007)
The Cre/loxP-system has become the system of choice for the generation of conditional so-called knockout mouse strains, i.e. the tissue-specific disruption of expression of a certain target gene. We here report the loss of expression of Cre recombina
Externí odkaz:
https://doaj.org/article/5283cbc28f1b4b5d8cf4ba458f48133f
Autor:
Michael Linnebacher, Mandy Beyer, Sergio Lilla, Christina S Mullins, Irene Hauzenberger, Kanstantsin Siniuk, Suneetha Nunna, Juergen Sonnemann, Martin Westermann, Christian Marx, Thorsten Heinzel, Oliver D. K. Maddocks, Oliver H. Kraemer, Andrea Piee-Staffa, Francesco Neri, Lisa Marx-Bluemel, René Thierbach, Said Kdimati, Zhao-Qi Wang, Tobias Wagner, Felix B. Meyer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3431d40d016840c1d0e24efef640c7
https://doi.org/10.1002/1878-0261.13060/v2/response1
https://doi.org/10.1002/1878-0261.13060/v2/response1