Zobrazeno 1 - 10
of 21
pro vyhledávání: '"René Thürmer"'
Autor:
René Thürmer
Synthetic peptides are of increasing importance as a class of substances used in medicinal products and the number of applications for marketing authorization has increased steadily in recent years. Based on European quality guidelines, international
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66e494da6a615c1f0f4e7af54c689531
https://doi.org/10.1039/9781788016445-00031
https://doi.org/10.1039/9781788016445-00031
Autor:
Luigi Calzolai, Vincent A. Hackley, Patrick Boisseau, Didier Bazile, Patricia Urbán, Margriet V. D. Z. Park, Sven Even F. Borgos, Gert Roebben, Karin Cederbrant, Lada Leyens, Blanka Halamoda-Kenzaoui, Simon Baconnier, Marina A. Dobrovolskaia, Valérie Zuang, Tiziana Di Francesco, Neill J. Liptrott, Gerrit Borchard, Anil K. Patri, Rogério Gaspar, Thierry Bastogne, René Thürmer, Matthias Roesslein, Belén Gracia, Gabriella Di Felice, Susanne Bremer-Hoffmann
Publikováno v:
Regulatory Toxicology and Pharmacology
Regulatory Toxicology and Pharmacology, Elsevier, 2019, 106, pp.187-196. ⟨10.1016/j.yrtph.2019.04.011⟩
Regulatory Toxicology and Pharmacology, 2019, 106, pp.187-196. ⟨10.1016/j.yrtph.2019.04.011⟩
Regulatory toxicology and pharmacology
Regulatory Toxicology and Pharmacology, Elsevier, 2019, 106, pp.187-196. ⟨10.1016/j.yrtph.2019.04.011⟩
Regulatory Toxicology and Pharmacology, 2019, 106, pp.187-196. ⟨10.1016/j.yrtph.2019.04.011⟩
Regulatory toxicology and pharmacology
An early dialogue between nanomedicine developers and regulatory authorities are of utmost importance to anticipate quality and safety requirements for these innovative health products. In order to stimulate interactions between the various communiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1098462eeaef174c7ace7d98d3b7e0a6
https://pubmed.ncbi.nlm.nih.gov/31051191
https://pubmed.ncbi.nlm.nih.gov/31051191
Autor:
Mansoor M. Amiji, Marco Araújo, Tomohiro Asai, Svetlana Avvakumova, Cristina C. Barrias, Hikmet Budak, John C. Burnett, Maria T. Cambria, Wen Cao, Bárbara Carreira, Devika B. Chithrani, Miriam Colombo, Guglielmo G. Condorelli, João Conniot, Noemi S. Csaba, Falk Ehmann, Tália Feijão, Cláudia S.M. Fernandes, Fabrícia Saba Ferreira, Helena F. Florindo, Sidónio C. Freitas, Elisabetta Galbiati, Rogério S. Gaspar, Maria Gonzalez-Pajuelo, Leaf Huang, Peng Huang, Yan Huang, Gregory A. Hudalla, Babar Hussain, Olga Iranzo, Christine Janas, Alexander N. Kharlamov, Priyadarshi Kumar, Hasan Kurt, Victoria Leiro, Jing Lin, Shichao Lin, Shasha Li, Zibiao Li, M. Victoria Lozano, Maria Cristina L. Martins, Ana I. Matos, Serena Mazzucchelli, Liane I.F. Moura, Faheem Muhammad, Naoto Oku, Paula Parreira, Ana Paula Pêgo, Carina Peres, Ruben Pita, Davide Prosperi, Antti Rahikkala, Ana C.A. Roque, Jessica M. Rosenholm, Rany Rotem, Vanessa Sainz, Manuel J. Santander-Ortega, Hélder A. Santos, Dillon T. Seroski, Ana L. Silva, Liana C. Silva, Amit Singh, Alejandro Sosnik, Daniela Teixeira, Gonçalo D.G. Teixeira, René Thürmer, Lungile N. Thwala, Ana L. Torres, Cristina Tudisco, Fernanda Pires Vieira, Matthias G. Wacker, Akira Wada, Hui Wei, Swee Liang Wong, Jiangjiexing Wu, Jia Yao, Meral Yüce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af8ad9b13d5a05f047b6d51d489ab33
https://doi.org/10.1016/b978-0-323-50878-0.01002-8
https://doi.org/10.1016/b978-0-323-50878-0.01002-8
Nanomedicines simultaneously present themselves with a wide range of technological, scientific, regulatory, and legal challenges. Each of these challenges requires an early awareness, appropriate scientific and methodological expertise, and consensus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a072b97993f7dfa9ccd668f9c0f762
https://doi.org/10.1016/b978-0-323-50878-0.00022-7
https://doi.org/10.1016/b978-0-323-50878-0.00022-7
Autor:
Heidemarie Ratsch, Gerhard Stiens, Andrew Pickett, Dirk Dressler, Dorothea Sesardic, Manfred Liebsch, Irmela Ruhdel, Birgit Kegel, Andreas Luch, Peter D. Thornton, Gerd Bicker, Martin Vey, Catherine Milne, Sarah Adler, Hans Bigalke, Joan Fitzgerald, Heide Heuschen, Frank Gessler, Christopher Bishop, René Thürmer, Martin L. Stephens, Jörg Blümel, Horst Spielmann, Barbara Grune
Publikováno v:
Alternatives to Laboratory Animals. 38:315-330
An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef209315b1946b279a0fca5c256edca
https://doi.org/10.1177/026119291003800401
https://doi.org/10.1177/026119291003800401
Autor:
René Thürmer, Zbigniew Kałuża, Piotr Krajewski, Wolfgang Voelter, Marek Chmielewski, Michael P. Williamson, Lech Kozerski, Bartłomiej Furman
Publikováno v:
Scopus-Elsevier
A comparison of steady-state NOE coefficients measured for vinyl-substituted isopropyl ethers with conformations generated by a molecular mechanics program allowed a characterization of the most favorable ground state conformations. With high confide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84eeb05f1441b0e90ce65fdd2f757c8f
https://doi.org/10.1039/a807624c
https://doi.org/10.1039/a807624c
Autor:
René Thürmer, W. Schmitt-Sody, Raed A. Al-Qawasmeh, U. Korff, Hartmut Echner, Mark Meisenbach, Angelika Weiler, Wolfgang Voelter
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:398-402
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f7c7ae79d6f79a34e5bf09d54634334
https://doi.org/10.1002/(sici)1097-0231(19980415)12:7<398::aid-rcm171>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19980415)12:7<398::aid-rcm171>3.0.co
Publikováno v:
Liebigs Annalen. 1997:1871-1876
A new strategy for the construction of the O-glycoside bond in the nephritogenoside unit using the phenylsulfenyl method is reported. The readily accessible phenylsulfinyl glycoside proved to be an excellent glycosyl donor, leading to high yields and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8588c97de9282ca6d122e5d7dad68783
https://doi.org/10.1002/jlac.199719970910
https://doi.org/10.1002/jlac.199719970910
Autor:
René Thürmer, Wolfgang Voelter, Zbigniew Kałuża, Sergiej Molotov, Marek Chmielewski, Bartłomiej Furman
Publikováno v:
Tetrahedron. 53:5883-5890
[2+2]Cycloaddition of chlorosulfonyl isocyanate to 3-O-vinyl ethers derived from D-glucose and D-glucuronolactone proceeded with an excellent stereoselectivity to provide azetidin-2-ones with (R) configuration at C-4′. Intramolecular N-alkylation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceed27df30e9969a9d74035a3bc61fe8
https://doi.org/10.1016/s0040-4020(97)00248-2
https://doi.org/10.1016/s0040-4020(97)00248-2
Publikováno v:
Journal f�r Praktische Chemie/Chemiker-Zeitung. 338:320-326
Synthesis of Chiral Multifunctional Polycyclic Furanoids via Annulation of Pyranosides A new strategy to chiral polyfunctionalized furanoids from 2, 3, 4, 7, 8, 9, 11, 12, 14, 15, 17 and 18 from cis-orientated epoxypyranosetriflates 1 and 6 and diani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2edaf33d5fb1c1a531a586da92f81655
https://doi.org/10.1002/prac.19963380164
https://doi.org/10.1002/prac.19963380164