Zobrazeno 1 - 10
of 32
pro vyhledávání: '"René Staritzbichler"'
Detecting Pre-Analytically Delayed Blood Samples for Laboratory Diagnostics Using Raman Spectroscopy
Autor:
Pascal Hunold, Markus Fischer, Carsten Olthoff, Peter W. Hildebrand, Thorsten Kaiser, René Staritzbichler
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7853 (2023)
In this proof-of-principle study, we systematically studied the potential of Raman spectroscopy for detecting pre-analytical delays in blood serum samples. Spectra from 330 samples from a liver cirrhosis cohort were acquired over the course of eight
Externí odkaz:
https://doaj.org/article/ffed899d43b5419da0eec485060264d6
Autor:
René Staritzbichler, Edoardo Sarti, Emily Yaklich, Antoniya Aleksandrova, Marcus Stamm, Kamil Khafizov, Lucy R Forrest
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0239881 (2021)
The alignment of primary sequences is a fundamental step in the analysis of protein structure, function, and evolution, and in the generation of homology-based models. Integral membrane proteins pose a significant challenge for such sequence alignmen
Externí odkaz:
https://doaj.org/article/98f0fed9026c444f86ee7c4fc3c06488
Autor:
René Staritzbichler, Pascal Hunold, Irina Estrela-Lopis, Peter Werner Hildebrand, Berend Isermann, Thorsten Kaiser
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256045 (2021)
Raman spectroscopy has shown to be a promising method for the examination of biomedical samples. However, until now, its efficacy has not been established in clinical diagnostics. In this study, Raman spectroscopy's potential application in medical l
Externí odkaz:
https://doaj.org/article/5cad61701f074d709098ba14c62d7639
Autor:
Jens Schumacher, Tijana Bacic, René Staritzbichler, Matin Daneschdar, Thorsten Klamp, Philipp Arnold, Sabrina Jägle, Özlem Türeci, Jürgen Markl, Ugur Sahin
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-21 (2018)
Abstract Background Virus-like-particles (VLPs) are attractive nanoparticulate scaffolds for broad applications in material/biological sciences and medicine. Prior their functionalization, specific adaptations have to be carried out. These adjustment
Externí odkaz:
https://doaj.org/article/3bd1aa9bed834ac187f6711b00a9d1f1
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57731 (2013)
Few sequence alignment methods have been designed specifically for integral membrane proteins, even though these important proteins have distinct evolutionary and structural properties that might affect their alignments. Existing approaches typically
Externí odkaz:
https://doaj.org/article/dafe639f97854629a3c6e9bb86fdd10d
Publikováno v:
Bioinformatics. 39
Motivation The SmoothT software and webservice offers the construction of pathways from an ensemble of conformations. The user provides an archive of molecule conformations in Protein Databank (PDB) format, from which a starting and a final conformat
Autor:
Michelle Kampfrath, René Staritzbichler, Guillermo Pérez Hernández, Alexander S Rose, Johanna K S Tiemann, Gerik Scheuermann, Daniel Wiegreffe, Peter W Hildebrand
Publikováno v:
Kampfrath, M, Staritzbichler, R, Hernández, G P, Rose, A S, Tiemann, J K S, Scheuermann, G, Wiegreffe, D & Hildebrand, P W 2022, ' MDsrv : visual sharing and analysis of molecular dynamics simulations ', Nucleic Acids Research, vol. 50, no. W1, pp. W483-W489 . https://doi.org/10.1093/nar/gkac398
Molecular dynamics simulation is a proven technique for computing and visualizing the time-resolved motion of macromolecules at atomic resolution. The MDsrv is a tool that streams MD trajectories and displays them interactively in web browsers withou
Autor:
Michelle Philipp, Christopher W. Moth, Nikola Ristic, Johanna K.S. Tiemann, Florian Seufert, Jens Meiler, Peter W. Hildebrand, Amelie Stein, Daniel Wiegreffe, René Staritzbichler
The possible effects of mutations on stability and function of a protein can only be understood in the context of protein 3D structure. The MutationExplorerwebserver maps variants onto protein structures and allows users to study variation by inputti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ab78a954a24d19c336ea4da23a21aa5
https://doi.org/10.1101/2023.03.23.533926
https://doi.org/10.1101/2023.03.23.533926
Autor:
René Staritzbichler, Emily Yaklich, Edoardo Sarti, Nikola Ristic, Peter W Hildebrand, Lucy R Forrest
Publikováno v:
Nucleic Acids Res
Nucleic Acids Research
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac391⟩
Nucleic Acids Research
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac391⟩
The AlignMe web server is dedicated to accurately aligning sequences of membrane proteins, a particularly challenging task due to the strong evolutionary divergence and the low compositional complexity of hydrophobic membrane-spanning proteins. Align
Autor:
Sebastian Canzler, Markus Fischer, David Ulbricht, Nikola Ristic, Peter W Hildebrand, René Staritzbichler
Publikováno v:
Bioinformatics Advances. 2
Motivation Protein–protein interactions (PPIs) play an essential role in a great variety of cellular processes and are therefore of significant interest for the design of new therapeutic compounds as well as the identification of side effects due t