Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma

Autor: Maren Schmiester, René Maier, René Riedel, Pawel Durek, Marco Frentsch, Stefan Kolling, Mir-Farzin Mashreghi, Robert Jenq, Liangliang Zhang, Christine B. Peterson, Lars Bullinger, Hyun-Dong Chang, Il-Kang Na

Publikováno v: Gut Microbes, Vol 14, Iss 1 (2022)

Modulation of commensal gut microbiota is increasingly recognized as a promising strategy to reduce mortality in patients with malignant diseases, but monitoring for dysbiosis is generally not routine clinical practice due to equipment, expertise and

Externí odkaz: https://doaj.org/article/131978702d9042d08878dcd1673b4c7e

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow

Autor: René Riedel, Richard Addo, Marta Ferreira-Gomes, Gitta Anne Heinz, Frederik Heinrich, Jannis Kummer, Victor Greiff, Daniel Schulz, Cora Klaeden, Rebecca Cornelis, Ulrike Menzel, Stefan Kröger, Ulrik Stervbo, Ralf Köhler, Claudia Haftmann, Silvia Kühnel, Katrin Lehmann, Patrick Maschmeyer, Mairi McGrath, Sandra Naundorf, Stefanie Hahne, Özen Sercan-Alp, Francesco Siracusa, Jonathan Stefanowski, Melanie Weber, Kerstin Westendorf, Jakob Zimmermann, Anja E. Hauser, Sai T. Reddy, Pawel Durek, Hyun-Dong Chang, Mir-Farzin Mashreghi, Andreas Radbruch

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

Memory B cells are important for protecting the host from pathogen rechallenge, but their properties and locations remain ill-defined. Here the authors show, using single-cell transcriptomics and repertoire analyses, that mouse spleen and bone marrow

Externí odkaz: https://doaj.org/article/d1c99a7f8c7f4d7ab186f53fdfc1db4e

Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development

Autor: Victor Greiff, Ulrike Menzel, Enkelejda Miho, Cédric Weber, René Riedel, Skylar Cook, Atijeh Valai, Telma Lopes, Andreas Radbruch, Thomas H. Winkler, Sai T. Reddy

Publikováno v: Cell Reports, Vol 19, Iss 7, Pp 1467-1478 (2017)

Antibody repertoire diversity and plasticity is crucial for broad protective immunity. Repertoires change in size and diversity across multiple B cell developmental stages and in response to antigen exposure. However, we still lack fundamental quanti

Externí odkaz: https://doaj.org/article/1feff7832d134a3ea39a09c4125ab16f

Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle

Autor: Paula Münkler, Niklas Klatt, Katharina Scherschel, Pawel Kuklik, Christiane Jungen, Ersin Cavus, Christian Eickholt, Jan Christoph, Marc D Lemoine, Torsten Christ, Stephan Willems, René Riedel, Paulus Kirchhof, Christian Meyer

Publikováno v: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, vol 25, iss 2

Aims Cardiac arrhythmia originating from the papillary muscle (PM) can trigger ventricular fibrillation (VF) and cause sudden cardiac death even in the absence of structural heart disease. Most premature ventricular contractions, however, are benign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16bbfef1b8be56a231147594476234a9
https://doi.org/10.1093/europace/euac126

Traditional Grain-Based vs. Commercial Milk Kefirs, How Different Are They?

Autor: Neubauer, Fatemeh Nejati, Charlotte C. Capitain, Jannike Lea Krause, Gi-Ung Kang, René Riedel, Hyun-Dong Chang, Jens Kurreck, Stefan Junne, Philipp Weller, Peter

Publikováno v: Applied Sciences; Volume 12; Issue 8; Pages: 3838

Traditional kefir, which is claimed for health-promoting properties, is made from natural grain-based kefir, while commercial kefirs are made of defined mixtures of microorganisms. Here, approaches are described how to discriminate commercial and tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::a0540ea67404c08cf02b82e2afb2e4b1